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I can’t even drink a single cup of coffee without shaking and getting intense anxiety.
Perhaps someday we'll discover a coffee tolerance gene.
I have the rapid variant but could not sleep well on 6 cups.
> consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day (fully adjusted OR 1.53, 95% CI 1.28, 1.83) 6+ cups! That’s a cranial marinade.
The scientific definition of a 'cup' of coffee is important. Usually this is defined as 4 ounces of brewed coffee, which means a normal mug of coffee (which can fit something like 10 oz) would be 2.5 cups! So, for most people's definition of a 'cup' of coffee, they really only mean 2.5 'mugs' of coffee.
Espresso? Weak americano? Strong? And then even: there is often more caffeine in a cup of filter coffee than in an espresso. Weird but true. So it differs quite a lot what you drink.
I know someone who drinks 15 cups a day, but they are very very weak. And another drank 20 stong ones a day. Myself I used to drink 10 easily, not anymore
The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.
> consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day (fully adjusted OR 1.53, 95% CI 1.28, 1.83) 6+ cups! That’s a cranial marinade.
The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.
Considering the very early effects of dementia start to impact people sometimes decades before it becomes bad enough that they are diagnosed, it's certainly possible that extreme coffee consumption is some kind of self-medication mechanism. Anecdotally, I've seen this a lot with adults with undiagnosed ADHD (including myself until 26). Caffeine can be a (very shitty) alternative to proper stimulant medication that pe…
> consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day (fully adjusted OR 1.53, 95% CI 1.28, 1.83) 6+ cups! That’s a cranial marinade.
I stopped cold turkey for a while but nowadays have settled on more like 1-2 a day and never after a specific time of day (for me I hard stop at 3pm). Having any more than this or after this time kills my sleep immediately.
The article is not claiming causal link, but this is still interesting. >After full covariate adjustment, consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day Coffee is stimulant just like some Alzheimer medications used to treat symptoms. It would be interesting to see if people increase coffee consumption with cognitive decline.
I'm wagering that these people are just chronically under-slept, using higher amounts of coffee to compensate. The link between chronic poor sleep and dementia is well established.
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--- About the subject, could be indeed that people with early dementia, have sleep deprivation so they need more coffee...