If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.
i love this idea. worldbank or imf or gates or thiel foundation compensates the company for opening the patent for the benefit of humanity.
Moderna's mRNA cancer vaccine works better than thought
71–80 of 258 posts
Re: Moderna's mRNA cancer vaccine works better than thought
#72Earlier quoted context omitted.
You should do the healthy things to avoid cancer in the first place, but once you are diagnosed with a cancer with high mortality rate, it's a whole different calculation in terms of risks vs benefits compared to Covid-19.
>You should do the healthy things to avoid cancer in the first place What are those?
Re: Moderna's mRNA cancer vaccine works better than thought
#73If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.
Re: Moderna's mRNA cancer vaccine works better than thought
#74Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.
> failed clinical trials in the 2000s and 2010s We didn’t start testing neoantigen mRNA cancer vaccines until 2017 [1]. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942458/
Re: Moderna's mRNA cancer vaccine works better than thought
#75Re: Moderna's mRNA cancer vaccine works better than thought
#76Earlier quoted context omitted.
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> the ones for the CV vaccine were listed on many pages of tiny text (both from Pfizer and from Moderna) The size of the pages side effects were written on says absolutely nothing about what the side effects are or their severity. > Then there are the long term consequences, many studies keep coming out with surprises (recent buzzword “Ribosomal frameshift” Ribosomal frameshift is in itself not a “long term consequen…
Naive question: Do they say what the side effects are and their severity in an easily accessible manner somewhere?
Re: Moderna's mRNA cancer vaccine works better than thought
#77Re: Moderna's mRNA cancer vaccine works better than thought
#78Earlier quoted context omitted.
> Well yes, in completely absurd and unrealistic situation the risk of taking vaccine might be larger than that of Covid-19. What about a person living in simple solitude who works remotely and orders everything in? This is a realistic, non-absurd scenario and they would possibly risk getting Covid-19 on their way to the appointment of getting the vaccine.
I don’t think anyone would care about such a person opting not to get a vaccine. But this describes, pretty much by definition, a very small portion of a society.
Re: Moderna's mRNA cancer vaccine works better than thought
#79Earlier quoted context omitted.
mRNA will eventually save the day for everyone, including for perfectly healthy individuals, but to me as a healthy 40yo person, with no known immunity issues, not overweight etc. etc. it is in my opinion still too risky to take just like that. It's an interesting take. From what we know so far, the risk from taking vaccine is much smaller than from covid infection. You might counter this with highlighting the "so fa…
There's a key difference here that cancer mRNA vaccine you are taking after you've been diagnosed with cancer. Otherwise for Coronavirus vaccines you couldn't argue that risks are much smaller for any given person under any given conditions. E.g. a person could be completely isolated for the next 10 years and have virtually 0% chance of getting Covid-19, so in this case there's no calculation that could show a vaccin…
Re: Moderna's mRNA cancer vaccine works better than thought
#80Earlier quoted context omitted.
There are maybe no effects that we know about right now. Different people have different opinions on what their risk tolerance is, so there could be people that may outright disagree with your statement. And there were even fewer such effects when the vaccines have rolled out back in 2020 with emergency approval, but without being used “in production” beforehand. Now we know much more about the mRNA platform, but I s…
You should do the healthy things to avoid cancer in the first place, but once you are diagnosed with a cancer with high mortality rate, it's a whole different calculation in terms of risks vs benefits compared to Covid-19.