Earlier quoted context omitted.
What kind of side effects?
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Moderna's mRNA cancer vaccine works better than thought
41–50 of 258 posts
Re: Moderna's mRNA cancer vaccine works better than thought
#42Earlier quoted context omitted.
mRNA will eventually save the day for everyone, including for perfectly healthy individuals, but to me as a healthy 40yo person, with no known immunity issues, not overweight etc. etc. it is in my opinion still too risky to take just like that. It's an interesting take. From what we know so far, the risk from taking vaccine is much smaller than from covid infection. You might counter this with highlighting the "so fa…
There's a key difference here that cancer mRNA vaccine you are taking after you've been diagnosed with cancer. Otherwise for Coronavirus vaccines you couldn't argue that risks are much smaller for any given person under any given conditions. E.g. a person could be completely isolated for the next 10 years and have virtually 0% chance of getting Covid-19, so in this case there's no calculation that could show a vaccin…
Otherwise for Coronavirus vaccines you couldn't argue that risks are much smaller for any given person under any given conditions. E.g. a person could be completely isolated for the next 10 years and have virtually 0% chance of getting Covid-19, so in this case there's no calculation that could show a vaccine being with more favourable benefits/risks.
Well yes, in completely absurd and unrealistic situation the risk of taking vaccine might be larger than that of Covid-19.
Re: Moderna's mRNA cancer vaccine works better than thought
#43Re: Moderna's mRNA cancer vaccine works better than thought
#44The headline borders on clickbait. The topic is a skin cancer vaccine, not a cancer vaccine.
Re: Moderna's mRNA cancer vaccine works better than thought
#45Earlier quoted context omitted.
For coronavirus maybe, because it's not much of danger for you in the first place, but those risks would be thousands of times more acceptable for cancer. There are no side effects observed from mRNA CV vaccines that could be worse when compared to cancers with 1%+ mortality rate. As a reminder you won't be taking it before the cancer, you would be taking it after the fact.
There are maybe no effects that we know about right now. Different people have different opinions on what their risk tolerance is, so there could be people that may outright disagree with your statement. And there were even fewer such effects when the vaccines have rolled out back in 2020 with emergency approval, but without being used “in production” beforehand. Now we know much more about the mRNA platform, but I s…
You should do the healthy things to avoid cancer in the first place, but once you are diagnosed with a cancer with high mortality rate, it's a whole different calculation in terms of risks vs benefits compared to Covid-19.
Re: Moderna's mRNA cancer vaccine works better than thought
#46If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.
> a big influx of money from all countries We don’t know how valuable this tech is. It could be worth trillions. It could be niche. Risk sharing, not cost, is the currency of deal making. > immediately publish details and surrender any patent mRNA vaccine production methods are tough, e.g. Moderna’s encapsulation technology. Add to that the personalisation required for these treatments, and we’re still far from econo…
> mRNA vaccine production methods are tough, e.g. Moderna’s encapsulation technology
…and were invented with publicly-funded research that they’ve now privatized, resulting in large death tolls from vaccine inequity in poor countries.
Re: Moderna's mRNA cancer vaccine works better than thought
#47Earlier quoted context omitted.
For coronavirus maybe, because it's not much of danger for you in the first place, but those risks would be thousands of times more acceptable for cancer. There are no side effects observed from mRNA CV vaccines that could be worse when compared to cancers with 1%+ mortality rate. As a reminder you won't be taking it before the cancer, you would be taking it after the fact.
There are maybe no effects that we know about right now. Different people have different opinions on what their risk tolerance is, so there could be people that may outright disagree with your statement. And there were even fewer such effects when the vaccines have rolled out back in 2020 with emergency approval, but without being used “in production” beforehand. Now we know much more about the mRNA platform, but I s…
Can you completely exclude that there are some awful long-term consequences of Covid-19 we do not know about and that could be prevented by vaccine?
Re: Moderna's mRNA cancer vaccine works better than thought
#48Re: Moderna's mRNA cancer vaccine works better than thought
#49Earlier quoted context omitted.
There are maybe no effects that we know about right now. Different people have different opinions on what their risk tolerance is, so there could be people that may outright disagree with your statement. And there were even fewer such effects when the vaccines have rolled out back in 2020 with emergency approval, but without being used “in production” beforehand. Now we know much more about the mRNA platform, but I s…
Can you completely exclude that there are some awful long-term consequences of Covid-19 we do not know about and that could be prevented by vaccine?
No, I can’t. Nobody can at this stage unfortunately.
Re: Moderna's mRNA cancer vaccine works better than thought
#50Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.
The side effects of most cancer treatments are aweful. How do they compare?
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