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What kind of side effects?
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Projecting further into the future, the world is going to be divided into those with access to and willingness to use biotechnology and those who don’t. Note that I am including things like fitness and health tracking apps under the umbrella of biotech.
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> a big influx of money from all countries We don’t know how valuable this tech is. It could be worth trillions. It could be niche. Risk sharing, not cost, is the currency of deal making. > immediately publish details and surrender any patent mRNA vaccine production methods are tough, e.g. Moderna’s encapsulation technology. Add to that the personalisation required for these treatments, and we’re still far from econo…
> mRNA vaccine production methods are tough, e.g. Moderna’s encapsulation technology …and were invented with publicly-funded research that they’ve now privatized, resulting in large death tolls from vaccine inequity in poor countries.
This is an odd complaint for this circumstance.
Those poor countries didn’t materially fund these vaccines’ development. And production was fundamentally constrained; nations entered into bidding wars to secure them. In the end, geopolitics dictated which vaccines—if any—poor people got. Covid vaccines were distributed through non-market channels.
If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.
A "big influx of money from all countries in the world" - if from governments themselves and not individual citizens buying - would in fact be a proof point against its claimed effectiveness, if forcing the otherwise free market (via easily-commonly captured political-government-institutional channels) is what's required to drive funding towards it, e.g. regulatory capture to provide profits when they may not actually be deserved-warranted - say by trying to get approval for a fraudulently approved product, e.g. "... the 26 pharmaceutical companies paid some $33 billion in fines during the 13-year period. The top 11 alone accounted for $28.8 billion" - https://www.pharmaceuticalprocessingworld.com/gsk-pfizer-and...
And arguably this is just the tip of the iceberg and the industry hasn't been held accountable for most of their fraud since the industrial complex formed.
This isn't just a problem with the pharmaceutical industry but with clearly corrupt-captured regulators like the FDA - who allowed this fraud to happen to begin with, missing or not checking into whatever lies were presented for the fraud to occur and the products to make it to market.
And that's why headlines like "Moderna's mRNA cancer vaccine works better than expected" should be taken with extreme skepticism.
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It's not a general vaccine , but a tailored one aimed at people being treated for cancers that have a high risk of it coming back. So it's not something that can just be handed out to everyone. I agree though if a general vaccine is created. I'm really looking forward to a future where this and heart disease or just merely annoying.
In particular: The vaccine works by instructing the body to make up to 34 “neoantigens.” These are proteins found only on the cancer cells, and Moderna personalizes the vaccine for each recipient so that it carries instructions for the neoantigens on their cancer cells.
Edit: Ah yes, why patent specifics when you can patent the umbrella which is akin to covering all bases - https://patents.google.com/patent/US10055540B2/en
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> but the ones for the CV vaccine were listed on many pages of tiny text (both from Pfizer and from Moderna). A whole bunch of OTC drugs carry CYA lists like this, it's not the gotcha you think it is. > but to me as a healthy 40yo person, with no known immunity issues, not overweight etc. My father is getting a stent put in for a 70% artery blockage. Older of course but skinny, looks after his health, exercises. He h…
Comorbidities run amok, known and unknown.
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There are maybe no effects that we know about right now. Different people have different opinions on what their risk tolerance is, so there could be people that may outright disagree with your statement. And there were even fewer such effects when the vaccines have rolled out back in 2020 with emergency approval, but without being used “in production” beforehand. Now we know much more about the mRNA platform, but I s…
You should do the healthy things to avoid cancer in the first place, but once you are diagnosed with a cancer with high mortality rate, it's a whole different calculation in terms of risks vs benefits compared to Covid-19.
What are those?
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Otherwise for Coronavirus vaccines you couldn't argue that risks are much smaller for any given person under any given conditions. E.g. a person could be completely isolated for the next 10 years and have virtually 0% chance of getting Covid-19, so in this case there's no calculation that could show a vaccine being with more favourable benefits/risks. Well yes, in completely absurd and unrealistic situation the risk…
> Well yes, in completely absurd and unrealistic situation the risk of taking vaccine might be larger than that of Covid-19. What about a person living in simple solitude who works remotely and orders everything in? This is a realistic, non-absurd scenario and they would possibly risk getting Covid-19 on their way to the appointment of getting the vaccine.
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You should do the healthy things to avoid cancer in the first place, but once you are diagnosed with a cancer with high mortality rate, it's a whole different calculation in terms of risks vs benefits compared to Covid-19.
Indeed. My view on vaccines is that they are not a cure but act as prevention agents.
For example rabies vaccines is not given to everyone, however after you get rabies you will be given that vaccine.
Vaccine in this case is a less harmful training tool to prepare you for the more harmful pathogen that may still be reaching its peak strength.
You can think of vaccines as a training tool. In some cases it might provide you with a response that can completely throw the pathogen out, in other cases it will just be able to fight it better.