Some Mexican pharmacies are selling full bottles of Adderall. But it's meth • Hacker News Board

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#61

Post by soudiere » Fri, Dec 22, 2023, 3:13 AM UTC

valec wrote: post #57

Modified3019 wrote: post #19

Earlier quoted context omitted.

No. That's like saying meth anol is basically eth anol. Sure they are chemically similar, but the differences are distinct and very important.

This is a terrible comparison. Meth[amphetamine] and Adderall [amphetamine] are extremely similar. Both act as triple monoamine releasers, releasing the most norepinephrine followed by dopamine followed by serotonin. The methyl group attached to the amine basically just helps it cross the blood brain barrier better and makes it more resistant to enzymatic destruction. This means it is a couple times more potent dose-…

Bingo

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#62

Post by soudiere » Fri, Dec 22, 2023, 3:17 AM UTC

standardUser wrote: post #18

dehrmann wrote: post #11

Isn't adderall basically prescription meth, anyway?

They are very similar, but the euphoria with Adderall is significantly less than with meth or other speed you'd buy on the street. For some people meth might be an effective substitute, but I think most people would find the high and the side-effects too distracting. Plus, that euphoric high increases the likelihood of abuse and addiction. I'd add that the people I've known who did a lot of meth tended to have physic…

People who do a lot of meth tend to smoke it.

Method of administration affects the time delay for euphoria. Smoke > Shooting > Eating.

People who do a lot of meth (or drugs outside of a prescription) tend to do as much as they can purchase and/or tolerate.

When you see someone who has a doctor (dealer) that gives them as much adderall as they want, illusions of differences between the two drugs rapidly fade. I'm talking about 100+mg a day, I've seen it happen, still have 50mg adderall pills from the person in the story.

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#63

Post by soudiere » Fri, Dec 22, 2023, 3:17 AM UTC

hotpotamus wrote: post #59

dehrmann wrote: post #11

Isn't adderall basically prescription meth, anyway?

This still blows my mind: https://www.goodrx.com/desoxyn Meth is apparently prescription meth.

Why does it blow your mind?

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#64

Post by soudiere » Fri, Dec 22, 2023, 3:26 AM UTC

epgui wrote: post #23

uxp100 wrote: post #3

Obviously not good, I’m just being a little glib. If correctly dosed I suppose people would be getting a somewhat more effective medication than they thought they were getting. Those who were getting caffeine or ibuprofen, not so much.

Why do you think methamphetamine would be more effective than amphetamines?

Higher potency, longer duration of action.

If your goal was to get inebriated (drinking), would everclear be more effective than vodka?

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#65

Post by soudiere » Fri, Dec 22, 2023, 3:29 AM UTC

BobaFloutist wrote: post #40

trashface wrote: post #13

Earlier quoted context omitted.

However DEA was claiming a few months ago that manufacturers had not used their allotted cap, so naturally the DEA did not raise it.

They were claiming that specific manufacturers had not used their allotted cap, so they refused to raise the cap of other manufacturers that had reached their cap.

DEA isn't the issue here.

The Justice Department brought the lawsuit against Purdue Pharma, and distributors are scared.

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#66

Post by adolph » Fri, Dec 22, 2023, 3:33 AM UTC

What would it take to make consumer systems to characterize molecules to see if they conform to a particular spec? The FDA et al are great and all if you live in the nice places of the world. They aren't so great for the rest of the world.

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#67

Post by soudiere » Fri, Dec 22, 2023, 3:39 AM UTC

The worst discussions we have on Hacker News are around healthcare and medicine.

For some reason the community refuses to apply a high of research and rigor to this topic, as if it's lesser than the non-sense we call computer science.

This entire debate is comical, the medical community's approach has been, by it's own admission, to throw various stimulants at ADHD. Methylphenidate, L-Amphetamine, D-Amphetamine, Lisdexamfetamine, etc.

By in large, everyone on this thread is pretending like there is a treasure trove of research demonstrating the superiority of Adderall (a racemic mixture of L & D amphetamine) to Methylamphetamine.

And that's just not true at all, there is a paucity of research on the subject. Meth = Bad because of the Germans and street drug users (who smoke an uncontrolled amount).

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#68

Post by hotpotamus » Fri, Dec 22, 2023, 4:44 AM UTC

soudiere wrote: post #63

hotpotamus wrote: post #59

Earlier quoted context omitted.

This still blows my mind: https://www.goodrx.com/desoxyn Meth is apparently prescription meth.

Why does it blow your mind?

Imagining a doctor writing a script for meth is pretty amusing, and maybe if that’s not a cool enough drug, they can hand out some crack or something.

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#69

Post by klipklop » Fri, Dec 22, 2023, 4:52 AM UTC

soudiere wrote: post #67

The worst discussions we have on Hacker News are around healthcare and medicine. For some reason the community refuses to apply a high of research and rigor to this topic, as if it's lesser than the non-sense we call computer science. This entire debate is comical, the medical community's approach has been, by it's own admission, to throw various stimulants at ADHD. Methylphenidate, L-Amphetamine, D-Amphetamine, Lisd…

Agreed.

I get tired of people that don’t have to deal with ADHD trying to apply some sort of morality to stimulants to treat the condition.

If something else actually worked people would gladly try it. Stimulants have so many downsides and side effects that most would never take it unless it was necessary for them to function. These people are not junkies looking to get high.

Not too surprised to see people say here stuff like “isn’t adderall just meth” dose and delivery methods are completely different.

Re: Some Mexican pharmacies are selling full bottles of Adderall. But it's meth

#70

Post by [deleted] » Fri, Dec 22, 2023, 4:58 AM UTC

kosherhurricane wrote: post #46

thaumasiotes wrote: post #36

Earlier quoted context omitted.

> The analogy is that they are both alcohol so they are the same right? Obviously not. They are the same. The difference is just that the bottle sold as "rubbing alcohol" has been intentionally poisoned.

Rubbing alcohol is isopropanol. Drinking alcohol is ethanol. You can get “industrial ethanol” that has some methanol added to prevent people from consuming it, and pay liquor tax on it. These are for chemists for specific applications. None of these things are “the same”.

[deleted]