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Mid-old cells are a potential target for anti-aging interventions in the elderly
81–90 of 121 posts
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#82Aside: figure 1 epitomizes everything that I hate about high-impact results-first journals: everything has to be packed into this one figure because nobody's expected to read anything else. No disrespect to the authors, these journals force you to express your work in this reader-hostile fashion where the most important parts of the paper wind up buried in the supplement.
Please don't pick the most provocative thing in an article or post to complain about in the thread. Find something interesting to respond to instead.
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#83Earlier quoted context omitted.
More likely you'll see all people rent organs; surprisingly EVEN poor people don't usually like death.
Sure, Society in its majestic equality will allow rich and poor people alike to rent a new bio-heart with youthenating agents for 1 million dollars a month.
I would hate to have to rely on society to provide services like that. Chances are nobody except the top political brass ever gets their bio-heart.
Thankfully, society in its majestic equality allows all people to establish or invest into startups. Total addressable market at $1M/month is much smaller than at $1k/month, which is still much smaller than at $100/month.
Assuming the expenses are low enough to still give the company a healthy and IMHO fair 20-50% profit margin at $1k/month or $100/month, it'd be dumb to price it at $1M/month. There would be thousands if not millions of companies offering this service - and a race to the bottom of the pricing.
Think about cars - companies are competing on lower prices and better features of these complex machines. There are many models for different kinds of buyers - not just a single option at $1M/month that'd allow the rich to move around.
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#84Earlier quoted context omitted.
I'll never understand this particular mindset. I mean, I can get _some_ of the fallacies involved. Pure envy. Scope insensitivity. But it just doesn't explain it for me. People buying high end audio gear have disposable income and spend obscene amounts of money on their hobby, and yet they get at most mild ridicule. Old people wanting _not to die_ get hate. How do people even get here?
the worry is of course that in 300 years Mark Zuckerberg will be having his big pan-American birthday part and all the plebes get treated to a 30 minute newsblast about it while eating their gruel. It's one thing to have music of lower quality, it's another to be old and dying and watching someone who was born a century before you gifted with youth and vitality. It's not hard to envision that situation if the rich ha…
That is so short-sighted. Practically all technological breakthroughs are expensive during the discovery and R&D process. Over time, engineering makes things more affordable at scale. And markets free to respond to supply and demand are the catalyst to make it work.
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#85Earlier quoted context omitted.
Its further evidence for a hypothesis on the mechanism of aging. Personally I just wanna know how aging works
Don't your telomeres get shorter, your DNA gets damaged and it doesn't replicate correctly anymore? Some animals can be immortal like lobsters but face limits like their physical size can kill them when they molt enough.
Yes, that's one of around 50 currently recognized factors of aging.
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#86Sure, "the" elderly. Everyone who is suffering from aging will be helped. No special treatment for powerful people, it'll be all about "the elderly".
It is a concern, look at the current monoclonal antibody alzheimer's treatment that's insanely expensive. Generally though it's in the interest of the rich to extend the useful lifespan of their workers, training workers from babies is expensive, so it could be cheaper to keep the current ones going for 200 years.
> so it could be cheaper to keep the current ones going for 200 years.
This sounds like a form of hell. I'd rather die than work for 200 years, I can already barely stomach working as long as I have to.
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#87Earlier quoted context omitted.
as stated, for equality reasons
Equality is meaningless. Why should we not have the same amount of ears as noses? That is inequality. Why should we use one fork instead of two for equality of the use of our hands and symmetry? Why not our keyboards be mirrored and equal too?
the whole point of a democratic state is power to the many. Maybe not to all, but certainly not unequally.
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#88Earlier quoted context omitted.
Why throw out the baby with the bath water, just because the rich will live longer, no one should. This is the feeling I get everytime I see a comment that it will be only for the rich and powerful. I don't think that will be the case, as there will be a gold rush once the possibility is proven and visible, everyone will try to get it, even the naysayers. It will be more like the crash of prices from the Spanish mine…
Think of all the mundane technology we use every single day that was, when it was first introduced, priced for the rich and powerful. And then imagine if we'd used that as a reason not to produce it.
And there is a lot of this sentiment around, specially with young people
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#89Aside: figure 1 epitomizes everything that I hate about high-impact results-first journals: everything has to be packed into this one figure because nobody's expected to read anything else. No disrespect to the authors, these journals force you to express your work in this reader-hostile fashion where the most important parts of the paper wind up buried in the supplement.
Please don't pick the most provocative thing in an article or post to complain about in the thread. Find something interesting to respond to instead. https://news.ycombinator.com/newsguidelines.html
Sorry, I wasn't intending to provoke.
Re: Mid-old cells are a potential target for anti-aging interventions in the elderly
#90Earlier quoted context omitted.
I'll never understand this particular mindset. I mean, I can get _some_ of the fallacies involved. Pure envy. Scope insensitivity. But it just doesn't explain it for me. People buying high end audio gear have disposable income and spend obscene amounts of money on their hobby, and yet they get at most mild ridicule. Old people wanting _not to die_ get hate. How do people even get here?
the worry is of course that in 300 years Mark Zuckerberg will be having his big pan-American birthday part and all the plebes get treated to a 30 minute newsblast about it while eating their gruel. It's one thing to have music of lower quality, it's another to be old and dying and watching someone who was born a century before you gifted with youth and vitality. It's not hard to envision that situation if the rich ha…
> it's another to be old and dying and watching someone who was born a century before you gifted with youth and vitality.
So, no one can have nicers things than me?