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One sleepless night can rapidly reverse depression for several days in mice

news.northwestern.edu

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Re: One sleepless night can rapidly reverse depression for several days in mice

#61

Post by bobbylarrybobby »

Waterluvian wrote: post #45
Hard_Space wrote: post #35

Having suffered from severe depression for over forty years, this reminds me of when I was 17, 18, etc. and suddenly discovered that if I stayed up for two days, the problem went away. So I knew this a very long time ago; but it always seemed to me that, besides smoking, this was just about one of the worst habits you could develop. By my mid-twenties, I had stopped.

My anxiety now is that using THC to sleep will cause issues long term. But without it I literally cannot get to sleep anymore. Edit: I regret pulling focus off parent comment and OP, but also deeply appreciate everyone’s comments.

If you cannot fall asleep without a drug then I'd say the drug has already caused issues

Re: One sleepless night can rapidly reverse depression for several days in mice

#62

Post by permo-w »

the problem with this is that sleep loss has myriad other consequences; something I often discover when I take ADHD medication. it's all well and good being productive for a day, but when you wake up the next day at 2pm, things start to fall apart

Re: One sleepless night can rapidly reverse depression for several days in mice

#64

Post by baxtr »

Kbelicius wrote: post #51
baxtr wrote: post #42

Earlier quoted context omitted.

Is your normal state depressed though? I don’t think it works for “normal” people.

The study was done on mice. Are there depressed mouse that are used in such experiments or is this just an opinion on why zdragnar might not feel these effects? This is a genuine question.

Ah god to know. I missed the mice part… I feel the same as OP. Whenever I miss a night I’m in a terrible mood. It was just my opinion.

Re: One sleepless night can rapidly reverse depression for several days in mice

#65

Post by IntrepidPig »

lucia-goldsmith wrote: post #53

The article "One Sleepless Night Can Rapidly Reverse Depression for Several Days" is a fascinating and promising piece of research. The findings suggest that sleep loss could be a potential treatment for depression, which is a debilitating condition that affects millions of people worldwide. I am particularly interested in the implications of this research for many people. I believe that this research could lead to n…

Was this written by an LLM?

Re: One sleepless night can rapidly reverse depression for several days in mice

#67

Post by hshsbs84848 »

throwaway4837 wrote: post #31

Waking up in the mornings helps reset my mental state sometimes. I wonder if it's related. If I have an early morning, I usually find that I'm more productive and have more energy to work out or focus on tasks. There's nothing more depressing than a cycle of waking up at 2pm because you stayed up until 5am. Waking up so late makes me feel like I'm wasting my life.

I’ve found that too

Somehow I feel really energized if I wake up like 2-3 hours before my regular time

But only if I haven’t done it in a while

Something about disrupting the pattern seems to throw off the usual morning grogginess

Re: One sleepless night can rapidly reverse depression for several days in mice

#69

Post by bdamm »

Waterluvian wrote: post #45
Hard_Space wrote: post #35

Having suffered from severe depression for over forty years, this reminds me of when I was 17, 18, etc. and suddenly discovered that if I stayed up for two days, the problem went away. So I knew this a very long time ago; but it always seemed to me that, besides smoking, this was just about one of the worst habits you could develop. By my mid-twenties, I had stopped.

My anxiety now is that using THC to sleep will cause issues long term. But without it I literally cannot get to sleep anymore. Edit: I regret pulling focus off parent comment and OP, but also deeply appreciate everyone’s comments.

Being unable to sleep is a common withdrawal symptom for cannabis use disorder. Congratulations, you are habituated, and long-term problems are likely accumulating as you are losing out on REM sleep and probably developing emotional and physical conditions related to cannabis use. Good luck!
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