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The Uselessness of Phenylephrine (2022)

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Re: The Uselessness of Phenylephrine (2022)

#172
post #80

Earlier quoted context omitted.

That's legitimate. The FDA's issue with oral phenylephrine is that it's metabolized in the gut before it gets to the sites where you want it to work.

I wonder if it will work as a suppository.

Yup!

https://my.clevelandclinic.org/health/drugs/20786-phenylephr...

Re: The Uselessness of Phenylephrine (2022)

#173

Earlier quoted context omitted.

I haven't tried lately (moved on to aother anti-histimines) but with a Driver's license, I could pretty readily get ahold of it. Then had to disengage based on what it was doing to my blood pressure.

Were you using a ‘D’ version? Like Claritin-D? I got that by accident once and my heart pounded like I was on speed. I’m highly sensitive to that stuff, same at the dentist the local anesthesia makes my heart race. Third generation antihistamines are amazing. Zyrtec changed my life. I used to majorly struggle with ‘hayfever’ as we called it, to the point it ruined my summer. I was miserable as a child, only winter ga…

Note that Zyrtec's patent expired in 2007, so it's now available as generic Cetirizine.

Re: The Uselessness of Phenylephrine (2022)

#174

Earlier quoted context omitted.

I haven't tried lately (moved on to aother anti-histimines) but with a Driver's license, I could pretty readily get ahold of it. Then had to disengage based on what it was doing to my blood pressure.

Were you using a ‘D’ version? Like Claritin-D? I got that by accident once and my heart pounded like I was on speed. I’m highly sensitive to that stuff, same at the dentist the local anesthesia makes my heart race. Third generation antihistamines are amazing. Zyrtec changed my life. I used to majorly struggle with ‘hayfever’ as we called it, to the point it ruined my summer. I was miserable as a child, only winter ga…

Surprised this is the only comment mentioning the amazing Zyrtec (with Cetirizine) (probably misspelled, even with the bottle in front of me), in poem form.

But yeah it does work, smashingly. Also I found changing my AC air filter helped.

Re: The Uselessness of Phenylephrine (2022)

#175
post #158
post #95

Earlier quoted context omitted.

If you walk up to the pharmacy counter at any Walgreens or CVS, literally the first thing you're going to see is a shelf of decongestants.

I can’t speak for your Walgreens or CVS, but at mine you’ll see a shelf full of phenylephrine-based decongestants only, because the pseudoephedrine-based ones are behind the counter and out of sight.

Lots of pharmacies display cards in the regular decongestant section that you can take up to the counter to get the ID-required OTC pills. It adds an annoying step, but they are hardly out of sight.

Re: The Uselessness of Phenylephrine (2022)

#176
post #27

Earlier quoted context omitted.

Indeed. I've known that phenylepherine is worthless for a long while, and just make it a point to buy a pack of the real stuff every 6 months or so, so that I always have it on hand when I need it. In my state, it's controlled - you have to get it from a pharmacist (though you can do so without a prescription) - they take your driver's license and don't allow you to purchase it too often.

You can buy 6 boxes of sudafed per month (24 doses each). Isn’t that more than the recommended (and probably safe) daily limit? I dont doubt your intentions but I don’t think you actually need 6 boxes per month + a stash.

When your kid gets sick late and the pharmacist leaves at 6, why not have a packs of pills wherever you are.

Or god forbid, you run out at work and forgot the CVS takes a siesta nationwide at 1:30.

Re: The Uselessness of Phenylephrine (2022)

#177

Earlier quoted context omitted.

You can't fight a war against inanimate objects. You can fight a war against drug addicts. You cannot possibly win a war against drug addicts without addressing the fundamental problem.

Most of us cannot make these drugs ourselves. To restrict them effectively would certainly curtail their abuse?

Vice or someone reports that you can make the new formulation, in a backpack, in a Walmart bathroom, with supplies you haven't even bought yet. Given that, and, well, the Internet, I'm sure making it isn't hard for an addict to learn how to make these drugs, even though it's not common knowledge and you and I can't do it.

Re: The Uselessness of Phenylephrine (2022)

#178
post #40

Earlier quoted context omitted.

Easily the best example of why the stupid federal law limiting access to a useful decongestant backfired.

You realize your "best example" is a joke, right?

Yes, the punchline of the joke is that synthesizing pseudoephedrine from meth is more convenient than buying Sudafed after the law on restricting sales ostensibly to reduce meth production.

i.e., the law didn't do much to halt meth production but did put a bunch of barriers around a useful drug _and_ promoted the use of phenylephrine instead, a useless drug in pill form. A huge net negative.

Re: The Uselessness of Phenylephrine (2022)

#179
post #160
post #136

Earlier quoted context omitted.

You can still get pseudoephedrine, for example Claritin D, the D for decongestant. It's not by prescription but you have to sign for it at the pharmacy desk, present ID, and I believe it's reported to FDA/DEA and there are limits to how much you can buy per month.

That's mostly right, but it's not reported to anyone. It came from the "The Combat Methamphetamine Epidemic Act of 2005" . If you want to sell pseudoephedrine, your org has to "self certify", keep a logbook purchasers have to sign, require ID, enforce the purchase limits, train employees, etc. But, the logbook doesn't go anywhere unless some investigation or audit prompts that. So, if you're a really determined cooke…

> So, if you're a really determined cooker, you can still go to a bunch of different stores...though you're leaving a paper trail.

Isn't meth a lot easier to come by these days? I have to imagine it's more convenient to cook street meth back into Sudafed to fix your stuffy nose than it is to cook Sudafed into meth to get your fix.

Re: The Uselessness of Phenylephrine (2022)

#180

Earlier quoted context omitted.

That is a US federal law (the Combat Methamphetamine Epidemic Act of 2005)

And now we've got a fentanyl epidemic filling the void and even more power handed to Mexican cartels since meth got harder to produce domestically. Drugs continue to win the war on drugs.

It's worse than that, because it's not actually a void that's being filled - meth production simply switched to a different pathway that's even more effective and potent. There's actually more meth than there was before the ban.

https://dynomight.net/p2p-meth/ "The main thing about P2P meth is that there's so much of it"

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