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Scientists may have found mechanism behind cognitive decline in aging

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Re: Scientists may have found mechanism behind cognitive decline in aging

#161

Post by Aerroon »

prox wrote: post #41
amelius wrote: post #28

Earlier quoted context omitted.

If you take a lot of vitamin d, make sure you also take vitamin k. Just a random source here because I'm too lazy: https://www.balancedwellbeinghealthcare.com/are-you-taking-v... > Because vitamin D is so good at improving calcium levels, by taking it alone you could be working to increase the calcification of your arteries instead of strengthening your bones so make sure to include K2 in your vitamin D supplement re…

Please note that overtaking vitamin D is unhealthy as well. It’s a hormone and I believe taking too much is damaging to the liver. But supplemental and when having a lack of Sun is probably a good balance. But if you can be in the sun your skin can make vitamin D.

You have to go really overboard with vitamin D3 to take too much of it. The daily recommendations so far are underestimating it. 4000 IU should be fine for adults. There are people that take 6000-10000 IU, but it's hard to say whether they might be suffering from some long term effects due to this.

You should take vitamin K2 with D3 though.

>But if you can be in the sun your skin can make vitamin D.

This is harder than people say. You need UVB light to hit your uncovered skin (glass blocks it entirely). The sun needs to be above 35-50 degrees in the sky. If it's below that (like in winter or evenings) then you won't get vitamin D from it.

Re: Scientists may have found mechanism behind cognitive decline in aging

#162

Post by nannal »

malauxyeux wrote: post #137
copperx wrote: post #93

Earlier quoted context omitted.

We can all prompt ChatGPT. Littering the web with its output is against good netizenship. I understand it's inevitable and a matter of time, but it's still aggravating.

> We can all prompt ChatGPT. I'm largely blind to this. If they're not wordy and overly polite, pasted ChatGPT answers just don't appear on my radar. Can someone help me out? What points to this answer in particular being from ChatGPT?

Chatgpt loves lists like this, then length and "tone" can be the most obvious indicators. You can modify those attributes through prompting but that should help find unmodified output

Re: Scientists may have found mechanism behind cognitive decline in aging

#163

Post by mpalmer »

malauxyeux wrote: post #137
copperx wrote: post #93

Earlier quoted context omitted.

We can all prompt ChatGPT. Littering the web with its output is against good netizenship. I understand it's inevitable and a matter of time, but it's still aggravating.

> We can all prompt ChatGPT. I'm largely blind to this. If they're not wordy and overly polite, pasted ChatGPT answers just don't appear on my radar. Can someone help me out? What points to this answer in particular being from ChatGPT?

Brief summarization that seems redundant to the topic because it's the model priming itself to generate a response in the requested form, which is usually a:

3-10 item list which mentions certain phrases related to the prompt every time ("nitric oxide" here).

Disclaimer about accuracy/expertise.

Re: Scientists may have found mechanism behind cognitive decline in aging

#164

Post by Broken_Hippo »

LoganDark wrote: post #55
prox wrote: post #41

Earlier quoted context omitted.

Please note that overtaking vitamin D is unhealthy as well. It’s a hormone and I believe taking too much is damaging to the liver. But supplemental and when having a lack of Sun is probably a good balance. But if you can be in the sun your skin can make vitamin D.

Note that windows typically block the majority of the radiation that allows you to make vitamin D, so even if the sun hits you every day through your window, it's still not a good substitute for a sunny walk every once in a while. My doctor told me to go out at noon every day, but anything is better than nothing.

Walking doesn't help me for 8 months of the year: There simply isn't strong enough sun to help. December days are only 4-5 hours long anyway. So, I was told to take a supplement from September to May.

My doctor told me to get 15 minutes a day from May through the end of August - and these should be walks with at least the arms exposed (Am in Norway, so this isn't always possible for me, the immigrant). Walking alone isn't always enough.

Re: Scientists may have found mechanism behind cognitive decline in aging

#165

Post by mpalmer »

Beefin wrote: post #125
copperx wrote: post #93

Earlier quoted context omitted.

We can all prompt ChatGPT. Littering the web with its output is against good netizenship. I understand it's inevitable and a matter of time, but it's still aggravating.

who cares how it was produced as long as it's useful...

Because it's not useful, it's an invitation to go fact check everything in the list.

Re: Scientists may have found mechanism behind cognitive decline in aging

#166

Post by fao_ »

nonethewiser wrote: post #132
fao_ wrote: post #81

Earlier quoted context omitted.

One would think the first step would be to look it up. > Most healthy people do not need to supplement with arginine because it is a component of all protein-containing foods[15] and can be synthesized in the body from glutamine via citrulline. I do not understand how someone can wish to know something, but refuse to expend effort to obtain the information they wish to seek? I hope it would be ok for you to explain t…

That doesn’t necessarily answer his question though and doesn’t even seem like a well reasoned point. Just because your body can produce something doesn’t mean it can’t benefit from more.

Likewise just because your body requires something doesn't mean that large doses of it are beneficial. See my followups, which address that and were written 30 minutes before your post :/

Re: Scientists may have found mechanism behind cognitive decline in aging

#167

Post by ilteris »

inconceivable wrote: post #140
bendbro wrote: post #44

Earlier quoted context omitted.

After my startup failed and I broke up with my girlfriend, my cognition massively changed: I was less creative, less quick, and I could see it reduce my ability to code. Otherwise, I lost libido, had paranoia in social interaction, and alcohol or marijuana would cause me paranoia. When I would ride my motorcycle on curvy roads, or when I would play a racing game or read a book, I couldn't get into a flow anymore. Thi…

fyi, this can happen in a successful startup/business also. this happened to me when i was stressed out of my mind and stuck doing work i hate for customers i didn't want after 10 years of running a biz. it took a breakup, a sale of the business, and nearly 2 years of doing nothing until i recovered. fwiw, the biggest takeaways the whole thing taught me are 1. be careful of what you wish for and 2. both attractive wo…

This is a refreshing comment to see here. Thank you.

Re: Scientists may have found mechanism behind cognitive decline in aging

#168

Post by kyriakos »

MagicMoonlight wrote: post #160

Eventually we will reach a point where humans are immortal. They’ll still die if they’re shot or clog their arteries etc but they won’t die purely based on running down a clock. There’s no inherent reason we have to die. It’s an evolved strategy to allow newer models to replace us. Turn that off and you’d stay around until physical damage and irreparable decay takes you out. It will be interesting from a societal sta…

Immortality raises a lot of ethical and philosophical questions that we will need to tackle if it ever becomes real. For example, if you live 200 years, how much would you remember of your first 30 years of life? Will that 200 year old person still technically be the same as the one that was born if he hardly remembers anything?

Re: Scientists may have found mechanism behind cognitive decline in aging

#169

Post by bluepod4 »

dazc wrote: post #150
bluepod4 wrote: post #130

Earlier quoted context omitted.

That’s strange for your dentist to give up money like that lol. But also, at dental cleanings they do things like polish your teeth. Do you also not require that?

As it was explained to me, flouride will work in repairing microscopic areas of decay so long as the surfaces of your teeth are ultra clean. My dentist insists that I see the hygienist every 3 months for descaling, cleaning and basic checks. For the cynics, the cost of this is negligible and I have not needed a filling or any other costly procedure for over a decade.

Ohhh, I misinterpreted your comment. I think other people did too.

It seemed as if you were saying that your dentist told you not to step foot in the dentist office at all for 18 months. But you just meant, the literal dentist doesn’t need to see you. Got it. I feel like this isn’t out of the ordinary now.

I always hear every 6 months for a cleaning. This new “3-month” information takes a bit away from your original statement since you are doing a bit more than what you suggested is required for maintaining healthy oral health.

Leading back to my original joke, maybe your dentist insisting that you need to get your teeth cleaned every 3 months is how they make their money lol!

Re: Scientists may have found mechanism behind cognitive decline in aging

#170

Post by scrollaway »

malauxyeux wrote: post #137
copperx wrote: post #93

Earlier quoted context omitted.

We can all prompt ChatGPT. Littering the web with its output is against good netizenship. I understand it's inevitable and a matter of time, but it's still aggravating.

> We can all prompt ChatGPT. I'm largely blind to this. If they're not wordy and overly polite, pasted ChatGPT answers just don't appear on my radar. Can someone help me out? What points to this answer in particular being from ChatGPT?

Some tell-tale signs (I work with GPT a lot as I mentioned in a sibling comment):

- It's a list, it's numbered, it's got pretty consistent markdown formatting. This is especially present with ChatGPT

- Title Casing In Each List Item

- Strong usage of the passive voice

- Strong CYA tone. "might promote", "studies suggest", "has been associated", "can convert", "possibly lowering", "thought to increase"

The general structure is very consistent with GPT too. Once you've seen a lot of sessions it's just... plain obvious. Especially if you step back and think: "Would people actually.. write like this?"

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