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Scientists may have found mechanism behind cognitive decline in aging

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131–140 of 314 posts

Re: Scientists may have found mechanism behind cognitive decline in aging

#131
post #124

I’m not sure what the proper name is for this idea, but I consider ageing to be a trade-off between cell-regeneration, which maintains youthfulness, and mutation-limitation, which reduces the chances of cancer. That is to say, if you “aged less”, you would get cancer more/sooner. Everything else, like the balance of chemicals in the body, I assume would be downstream of that.

I'm not a biologist, but I believe what you're talking about is telomerase?

Re: Scientists may have found mechanism behind cognitive decline in aging

#132
post #81

Earlier quoted context omitted.

I really want to know, why don't we all supplement with L-arginine long term? Time-release capsules are available and I have taken for numerous issues like RSI to great success. Whats the downside to long term usage?

One would think the first step would be to look it up. > Most healthy people do not need to supplement with arginine because it is a component of all protein-containing foods[15] and can be synthesized in the body from glutamine via citrulline. I do not understand how someone can wish to know something, but refuse to expend effort to obtain the information they wish to seek? I hope it would be ok for you to explain t…

That doesn’t necessarily answer his question though and doesn’t even seem like a well reasoned point. Just because your body can produce something doesn’t mean it can’t benefit from more.

Re: Scientists may have found mechanism behind cognitive decline in aging

#133
post #97

Earlier quoted context omitted.

But if your diet lacks kale, arugula, Swiss Chard, spinach, beets, cabbage, cauliflower, carrots and broccoli one might do something about it.

If someone tells me kale is carcinogenic imma lose it because it does not taste good. I’m not eating this for fun you know.

Have you only tried it raw? There are ways to cook it without losing too much nutrients. Cooked kale still has noticeable health benefits according to some studies I found.

Re: Scientists may have found mechanism behind cognitive decline in aging

#134

Earlier quoted context omitted.

I'd like to add(0, •) another item to your list: 0. Stop mouth breathing and do nasal breathing whenever possible because only the latter produces nitric oxide, see https://en.m.wikipedia.org/wiki/Biological_functions_of_nitr...

Mouth taping is not very popular outside some kinky circles.

No one said you'd need to tape your mouth to do nasal breathing.

Re: Scientists may have found mechanism behind cognitive decline in aging

#135
post #16

I've noticed a cognitive decline in myself the past couple years. I'm in my mid 30's though so I assume it's more related to long covid. One of the biggest side effects of long covid for me was horrible insomnia, which was killer. The insomnia is mostly gone, but I'm still not my previous cognitive self. It's terrifying to be honest.

Also, get checked up for Sleep Apnea. It is a truly life-ruining condition whose primary side effect is lost memory and cognitive function.

Holy shit this. I went years undiagnosed. Saw a dozen doctors. Couldn’t get an clear explanation for why I was always tired, brain fog, vision problems, joint pain, memory issues. The list goes on.

Then my _dentist_ of all people ordered a Watch-PAT take-home sleep test (took a lab sleep test, but it was useless) which finally revealed I was having more than 10 events per hour. The dentist made me a Herbst appliance to hold my airways open during sleep. My life is 100x better now.

Re: Scientists may have found mechanism behind cognitive decline in aging

#136
post #16

I've noticed a cognitive decline in myself the past couple years. I'm in my mid 30's though so I assume it's more related to long covid. One of the biggest side effects of long covid for me was horrible insomnia, which was killer. The insomnia is mostly gone, but I'm still not my previous cognitive self. It's terrifying to be honest.

I had the same after COVID. Took me many months to start feeling functional again. Any time I tried to think about something, it'd just... noise out? First 2-3 months were just awful

I went to a neurologist who said there's tons of people coming in with the same complaint after COVID, and since there's no literature on that yet, he couldn't really do anything.

It gets better.

Re: Scientists may have found mechanism behind cognitive decline in aging

#137
post #93
post #35

[flagged]

We can all prompt ChatGPT. Littering the web with its output is against good netizenship. I understand it's inevitable and a matter of time, but it's still aggravating.

> We can all prompt ChatGPT.

I'm largely blind to this. If they're not wordy and overly polite, pasted ChatGPT answers just don't appear on my radar.

Can someone help me out? What points to this answer in particular being from ChatGPT?

Re: Scientists may have found mechanism behind cognitive decline in aging

#138
post #35

[flagged]

What you listed here is essentially an evidence based diet and one of its most prominent proponents is Dr. Michael Greger with his works around "How not to die".

He for example features his Daily Dozen: https://nutritionfacts.org/daily-dozen-challenge/

Put in reverse: no meat, eggs, diary.

I might add that there are neuroprotective foods as well, just for reference: https://www.mdpi.com/1420-3049/15/5/3517

Re: Scientists may have found mechanism behind cognitive decline in aging

#139

Earlier quoted context omitted.

Mouth taping is not very popular outside some kinky circles.

No one said you'd need to tape your mouth to do nasal breathing.

Most of the problems with NO production happen during the night when people tend to breathe through the mouth, making them tired during the day. Moreover, their CO2 levels tank as well for a double negative effect from what was supposed to be a refreshing sleep.

Re: Scientists may have found mechanism behind cognitive decline in aging

#140
post #44
post #16

I've noticed a cognitive decline in myself the past couple years. I'm in my mid 30's though so I assume it's more related to long covid. One of the biggest side effects of long covid for me was horrible insomnia, which was killer. The insomnia is mostly gone, but I'm still not my previous cognitive self. It's terrifying to be honest.

After my startup failed and I broke up with my girlfriend, my cognition massively changed: I was less creative, less quick, and I could see it reduce my ability to code. Otherwise, I lost libido, had paranoia in social interaction, and alcohol or marijuana would cause me paranoia. When I would ride my motorcycle on curvy roads, or when I would play a racing game or read a book, I couldn't get into a flow anymore. Thi…

fyi, this can happen in a successful startup/business also. this happened to me when i was stressed out of my mind and stuck doing work i hate for customers i didn't want after 10 years of running a biz.

it took a breakup, a sale of the business, and nearly 2 years of doing nothing until i recovered.

fwiw, the biggest takeaways the whole thing taught me are 1. be careful of what you wish for and 2. both attractive women and customers want outcomes, they don't give a shit about your problems and 3. never forego vacations/holidays for work.

as for me, well - you know how the saying goes - it's always darkest before the dawn, and life is good now. for the time being. but i know that if i wake up one day and i'm feeling like a fucking pack mule for people who don't appreciate me, it's time for a massive rapid change, without the period of suffering this time.

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