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Scientists may have found mechanism behind cognitive decline in aging

news.cuanschutz.edu

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Re: Scientists may have found mechanism behind cognitive decline in aging

#11

Post by haldujai »

Aaargh20318 wrote: post #7
Etheryte wrote: post #4

...in mice.

Due to the way medication is developed, we basically only end up with medicine that works on humans + at least one other species. I wonder how many medications we have missed out on that would have worked on humans but never got to the human trial stage because it doesn’t work in any of the animal models we use.

This isn’t a medication it’s a mechanism study.

I would expect not many and certainly far less than the number of medications that worked in animals but did not work or harmed humans.

Re: Scientists may have found mechanism behind cognitive decline in aging

#12

Post by DyslexicAtheist »

Scientists may have found mechanism behind cognitive decline in aging, but there shall, in that time, be rumors of things going astray, and there shall be a great confusion as to where things really are, and nobody will really know where lieth those little things with the sort of raffia work base that has an attachment that one may confuse with clickbait.

Re: Scientists may have found mechanism behind cognitive decline in aging

#13

Post by DyslexicAtheist »

carrolldunham wrote: post #5
Etheryte wrote: post #4

...in mice.

People just jump to say this like it's a game now. The headline says 'may have found the mechanism'. It's not claiming anything that needs this

so "scientists baffled and confused" would have been more accurate :)

edit: I'm overthinking this, but the word "scientists" does a lot of heavy lifting in the headline. The number of things the human race in general and scientists especially are unsure about is vast. Putting a person in a white overcoat, spectacles, and pen in their pockets to lead the sentence with authority doesn't give them a chance of not looking dumb. Scientists in media language are 100% of the time more clownish than even politicians or any other profession.

Even the content in itself is garbage, in which case the headline does justice, or there was in fact something news-worthy but the meta-analysis by this article has missed it.

Re: Scientists may have found mechanism behind cognitive decline in aging

#15

Post by hollerith »

withinboredom wrote: post #9
Madmallard wrote: post #3

same mechanism for decline in the rest of the body???? Surely oxidation and dna mutations accumulating affects the brains similarly to how it affects everything else.

IIRC, brain cells don’t divide, so “random DNA changes” don’t apply, at least not in the way it would in the rest of the body. I could be totally wrong, I’m not a brain scientist.

A cell still needs its DNA (to make proteins among other things) even when it is not dividing.

Re: Scientists may have found mechanism behind cognitive decline in aging

#16

Post by swalsh »

I've noticed a cognitive decline in myself the past couple years. I'm in my mid 30's though so I assume it's more related to long covid. One of the biggest side effects of long covid for me was horrible insomnia, which was killer. The insomnia is mostly gone, but I'm still not my previous cognitive self. It's terrifying to be honest.

Re: Scientists may have found mechanism behind cognitive decline in aging

#18

Post by pja »

swalsh wrote: post #16

I've noticed a cognitive decline in myself the past couple years. I'm in my mid 30's though so I assume it's more related to long covid. One of the biggest side effects of long covid for me was horrible insomnia, which was killer. The insomnia is mostly gone, but I'm still not my previous cognitive self. It's terrifying to be honest.

Quality of sleep makes a huge difference to your mental faculties. If you could bottle it, the effect would be a multi, multi $billion drug.

Re: Scientists may have found mechanism behind cognitive decline in aging

#19

Post by [deleted] »

swalsh wrote: post #16

I've noticed a cognitive decline in myself the past couple years. I'm in my mid 30's though so I assume it's more related to long covid. One of the biggest side effects of long covid for me was horrible insomnia, which was killer. The insomnia is mostly gone, but I'm still not my previous cognitive self. It's terrifying to be honest.

[deleted]

Re: Scientists may have found mechanism behind cognitive decline in aging

#20

Post by digitcatphd »

DyslexicAtheist wrote: post #12

Scientists may have found mechanism behind cognitive decline in aging, but there shall, in that time, be rumors of things going astray, and there shall be a great confusion as to where things really are, and nobody will really know where lieth those little things with the sort of raffia work base that has an attachment that one may confuse with clickbait.

Thanks for the TL;DR
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