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Scientists may have found mechanism behind cognitive decline in aging

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Re: Scientists may have found mechanism behind cognitive decline in aging

#33
post #27
post #18

Earlier quoted context omitted.

Quality of sleep makes a huge difference to your mental faculties. If you could bottle it, the effect would be a multi, multi $billion drug.

Exercise tends to help.

Unless you also got PEM with your long COVID, then exercise makes it a lot worse. Bro science is dangerous.

Re: Scientists may have found mechanism behind cognitive decline in aging

#36
post #27
post #18

Earlier quoted context omitted.

Quality of sleep makes a huge difference to your mental faculties. If you could bottle it, the effect would be a multi, multi $billion drug.

Exercise tends to help.

My kids have started taking swim lessons at the Y, so i've been sneaking up stairs to run a mile during their lesson. I've thought about strength training etc, but I have no idea what i'm doing on those machines.

Can't say I feel any different, but it is enjoyable.

Re: Scientists may have found mechanism behind cognitive decline in aging

#37
post #24
post #16

I've noticed a cognitive decline in myself the past couple years. I'm in my mid 30's though so I assume it's more related to long covid. One of the biggest side effects of long covid for me was horrible insomnia, which was killer. The insomnia is mostly gone, but I'm still not my previous cognitive self. It's terrifying to be honest.

Are you taking vitamin d? If not you absolutely should. Magnesium at the same time as D3 and then glycine and another dose of magnesium before bed. This is the magic formula for me.

I've tried a variety of supplements, the only thing i've tried with any noticable effect is ashwagandha.

Re: Scientists may have found mechanism behind cognitive decline in aging

#38
post #27

Earlier quoted context omitted.

Exercise tends to help.

Unless you also got PEM with your long COVID, then exercise makes it a lot worse. Bro science is dangerous.

Don't think the sleep quality pill comment was aimed at long covid specifically.

Just because some people have conditions that prevent them from exercising it doesn't mean it isn't the healthy choice overall.

Re: Scientists may have found mechanism behind cognitive decline in aging

#39
post #4

...in mice.

Due to the way medication is developed, we basically only end up with medicine that works on humans + at least one other species. I wonder how many medications we have missed out on that would have worked on humans but never got to the human trial stage because it doesn’t work in any of the animal models we use.

Aspirin is famous for having teratogenic effects on rabbits and would never have been approved for humans if it were to be tested nowadays
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