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Taurine deficiency as a driver of aging

science.org

111–120 of 301 posts

Re: Taurine deficiency as a driver of aging

#112

Earlier quoted context omitted.

I asked ChatGPT "Is moderate consumption of energy drinks unhealthy?" and the answer was no. Moderate consumption is defined as "For adults, moderate consumption is typically defined as no more than 400 milligrams of caffeine per day, which is roughly equivalent to four cups of coffee or two 16-ounce cans of common energy drinks." I drink them moderately so maybe the taurine is healthy for me at my age, although exce…

Are you... treating a language model as a doctor?

Or I could use WebMD. What's the difference?

Re: Taurine deficiency as a driver of aging

#113
post #84

Obviously the real driver of aging is that there was no selective pressure to keep the organism working after sufficient semi-clones were brought online, and keeping an organism functional is a hard problem. The solution is to gain the ability to simulate the organism that results from a particular DNA sequence, understand the design problems in the organism, fix the problems, then alter human DNA to include the fixe…

But if the organism lived longer it would keep pumping semiclones. And if organisms are basically huge self-sustaining feedback loops, why won't they keep sustaining ... forever until some pressure forces them to decay

There are trade offs for living longer. For example, children of older fathers are more likely to have birth defects.

Re: Taurine deficiency as a driver of aging

#114
post #105

Earlier quoted context omitted.

You have a short memory. Not long ago you wrote the following > I know I won't change anyone's already set opinions here, but for anyone reading this and not sure what is being discussed: there's absolutely nothing wrong with consuming sucralose. Then I posted a link to a study showing Sucralose is toxic.

Yes and I'll stand by that statement. I think you'll find, once again, that nothing I said contradicts the statement you made , which is: > There are studies for and against artificial sweeteners. There are studies funded by industry. There is such a thing as corruption in science and corruption in regulatory agencies. The global artificial sweetener market size is $7 Billion. I get that you're on the "okay, they're…

You wrote

> there's absolutely nothing wrong with consuming sucralose

Well, there are studies showing that there is something wrong with consuming sucralose.

I posted a link to such a study. That contradicts your statement.

Re: Taurine deficiency as a driver of aging

#115

Earlier quoted context omitted.

Studied by whom for what goal? They're also some of the most astutely-avoided substances, with various products proudly proclaiming they don't contain them. Such markets could well potentially exist due to user experience trumping studies.

So I take it you're on the "okay, they're not" side of that divide? I mean, how many more decades does one need to really make a decision on these?

2-3 generations. Historically demonstrable as a metric to be sure about the ill effects of a new substance/tech. History is littered with examples of consumers & industry placing convenience & profits ahead of what's sensible to these ends.

Eg, X-rays - 60 years from invention, popularity, child use, "crazy" people claiming they're bad, to suspicion they might be, conservative study, realising they're screwed, all kinds of safety standards being applied, and acceptance.

Radiation, thalidomide, PCB's, DDT's, smoking, Asbestos, etc. Sometimes it can be faster or slower, but 2-3 human generations is also pragmatic as you can reasonably assess effects on offspring as well as sufficiently-aged pioneers.

I mean, why are people even considering artificial sweeteners? Isn't it only because it's taken us all several decades to realise refined sugar is fucked after initially thinking it was great if not at least "safe"?

I'm happy ingesting organic fruit, but I understand many out there prefer their bodies used as profit-making devices.

Re: Taurine deficiency as a driver of aging

#116

Obviously the real driver of aging is that there was no selective pressure to keep the organism working after sufficient semi-clones were brought online, and keeping an organism functional is a hard problem. The solution is to gain the ability to simulate the organism that results from a particular DNA sequence, understand the design problems in the organism, fix the problems, then alter human DNA to include the fixe…

There is selective pressure for aging because populations of organisms that don't age cannot evolve to adapt to new environments.

Re: Taurine deficiency as a driver of aging

#117
post #28

Earlier quoted context omitted.

Anecdata: a heavy (2 x 8oz cans/day) consumer of Red Bull I got sleep problems starting around 34. Can't be sure they are related, but Red Bull is definitely the main suspect.

I've developed sleep problems as I've gotten older, but I've never touched Red Bull. We can't draw any generalizable conclusions from isolated anecdotes like this.

Maybe for you or maybe not, but I need to write this out there: My wife (42 YO) started to experience sleep issues around a year ago. She tried with lots of stuff including delayed-release Melatonin, and nothing quite worked well. Until she started taking ZMA pills [1]. This supplement really solved her issues. I take "half dose" sporadically and really helps me get a full good deep night sleep.

It may or may not work for you, but it's one of those things that may be worth try it, and they sell it GNC and similar mainstreet stores.

[1] https://en.wikipedia.org/wiki/ZMA_(supplement)

Re: Taurine deficiency as a driver of aging

#118
post #114

Earlier quoted context omitted.

Yes and I'll stand by that statement. I think you'll find, once again, that nothing I said contradicts the statement you made , which is: > There are studies for and against artificial sweeteners. There are studies funded by industry. There is such a thing as corruption in science and corruption in regulatory agencies. The global artificial sweetener market size is $7 Billion. I get that you're on the "okay, they're…

You wrote > there's absolutely nothing wrong with consuming sucralose Well, there are studies showing that there is something wrong with consuming sucralose. I posted a link to such a study. That contradicts your statement.

You actually posted a link to a news article about a study, not a link to a study. And no, it doesn't contradict my statement that there's nothing wrong with consuming sucralose. It by itself is a piece of evidence, and doesn't by itself override decades of evidence.

Re: Taurine deficiency as a driver of aging

#119

Earlier quoted context omitted.

So I take it you're on the "okay, they're not" side of that divide? I mean, how many more decades does one need to really make a decision on these?

2-3 generations. Historically demonstrable as a metric to be sure about the ill effects of a new substance/tech. History is littered with examples of consumers & industry placing convenience & profits ahead of what's sensible to these ends. Eg, X-rays - 60 years from invention, popularity, child use, "crazy" people claiming they're bad, to suspicion they might be, conservative study, realising they're screwed, all ki…

> I mean, why are people even considering artificial sweeteners? Isn't it only because it's taken us all several decades to realise refined sugar is fucked after initially thinking it was great if not at least "safe"?

Can't speak for anyone else obviously, I use sucralose to sweeten plain nonfat greek yogurt for breakfast. It tastes like churned asshole without it, but it's otherwise a great food with everything I need for breakfast. Then I flavor it with either a certain number of calories, or artificial flavoring, depending on the day's goal.

I use sucralose in particular because it's what was available, but I'd be perfectly happy using aspartame or whatever instead if that's what was usable.

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