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Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

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Re: Ozempic drug supresses desire to smoke, drink and more?

#441

Earlier quoted context omitted.

If you're interested - not pushing an agenda. Here's what worked for this weird dude to not drink and stay fit. I used to lift and be real fit till about 40. Like bulky-lean looking, bench 400 10x with a 6pack. Had a lot to do with being on the road for work all over the world, and you sit at the gym at the hotel for an hour every night because of nothing else to do, and there are girls there also on business who you…

> I stopped using cocaine and for some reason gained weight, the post

Not at all, the two events are clearly separate in my account of history, and are actually about a decade apart. The weight gain, as with 99% of people, comes from a testosterone change once you approach 40yo.

It's really strange how you and a few other people just keep making up weird scenarios, then attacking those to make yourself feel superior. I don't get it. It was 1/4 book page of simple text. How is it possible to read something that simple, that short, and then make up something completely different in your head. This explains a lot of politics, but I don't get what people with that mental illness are on HN. Please stop. You are not superior - you have reading comprehension problems.

Re: Ozempic drug supresses desire to smoke, drink and more?

#442
post #57
post #23

I’m glad people are enjoying Ozempic. My experience from seeing a family member on it, is I would not touch it if I were a 500-pound alcoholic smoking two packs of cigarettes a day. That’s an exaggeration since it probably outweighs the health issues there, but only slightly. The person I know taking Ozempic has only lost weight (35 lbs) due to the fact that eating now makes her sick. She has been sapped of all energ…

Your relative’s sad story reminds me of a short story I read a few years ago about a miracle pill that leaves about 90% of its takers perfectly slim and able to stay that way eating anything, after a few truly disgusting initial days of elimination, but kills the other 10% gruesomely. Because it’s so wonderfully effective for the majority, there ends up being a ton of social and economic pressure for anyone even slig…

That is pretty unrealistic with 10% odds but I wonder what the odds would actually have to be for a drug like that to get so popular.

Re: Ozempic drug supresses desire to smoke, drink and more?

#443

Now if only it didn’t cost so damn much every month even under insurance =(

You can get these wholesale from China from "reputable" gray-market wholesalers who get the chemicals made at contract manufacturing facilities. BYO QA/QC though, as with all non-FDA drugs. That's the huge catch, and it sucks for consumers. Testing just for active ingredient is >$100 and takes about a month. Testing for proper buffering agents, harmful contaminants, microbial contamination, etc is essentially unavail…

Wow this is incredible, thanks for sharing! I was quoted $800/mo after insurance for a moderately low dose of Semaglutide (Ozempic)

Re: Ozempic drug supresses desire to smoke, drink and more?

#444
post #5

A drug that promotes weight loss, lessens the desire to smoke, drink, etc...sounds too good to be true? From what I have heard, all of these issues come back as soon as someone comes off the drug. So either a person is committing to a lifetime of being dependent on this drug, or a person is committing to some period of time of ideal living, followed by a possible time of depression after reverting to the status quo.

Imagine being 250 lbs and feeling like you are starving constantly, despite eating a lot every day. You decide to lose weight. You do something you hate, like calorie restriction and working out like a dog. You lose 80 lbs in 1 year. Bravo. Everyone tells you how great you look. You feel great. All that hard work was worth it. The fatness and a million other things really motivated you to do the hard work. I've done…

This perfectly encapsulates my experience. I'm hesitant to ask for this medication because of side effects and because it's got a 2 year limit in my country, so I don't want to go through it all then have to stop and ultimately put it all back on. Shit sucks, bro.

Re: Ozempic drug supresses desire to smoke, drink and more?

#445
post #435

Earlier quoted context omitted.

This isn't true. I am not dissociated when not actively undergoing the treatment. If anything, the after-effects of ketamine treatment alleviate my lifelong dissociation and other symptoms depression and PTSD. Something about the induced dissociation "wraps around" and snaps people back into fully being present. Have you ever had ketamine treatment? Where are you getting these conclusions?

Yes I did have two treatments. After the first treatment I really liked it and I thought I had my life back. All my debilitating symptoms were gone. Weeks after the second treatment I noticed that my depression and trauma is not gone. It just made me not constantly aware of it, if that makes sense. I was not clinically dissociated as well, just dissociated from the things that caused my suffering. I didn’t think that…

> Ketamine didn’t heal me, my perspective just changed

I thought that was the entire point of the treatment. Is that not the case?

Re: Ozempic drug supresses desire to smoke, drink and more?

#446
post #437

Earlier quoted context omitted.

>Only a few people have been reported to not relapse before 24 weeks. So what? Ketamine is a treatment, not a cure. Would you apply the same logic to insulin for T1 diabetes?

You are comparing apples to oranges my friend.

How so?

We don't know of any cure for depression, but with ketamine we have an effective rapid treatment.

Ketamine has a great therapeutic range, a well-understood side effect profile, and can bring a patient back from the brink of suicide in a matter of hours. It's also incredibly inexpensive to produce, on par with aspirin. Why shouldn't we use it?

Re: Ozempic drug supresses desire to smoke, drink and more?

#447
post #444

Earlier quoted context omitted.

Imagine being 250 lbs and feeling like you are starving constantly, despite eating a lot every day. You decide to lose weight. You do something you hate, like calorie restriction and working out like a dog. You lose 80 lbs in 1 year. Bravo. Everyone tells you how great you look. You feel great. All that hard work was worth it. The fatness and a million other things really motivated you to do the hard work. I've done…

This perfectly encapsulates my experience. I'm hesitant to ask for this medication because of side effects and because it's got a 2 year limit in my country, so I don't want to go through it all then have to stop and ultimately put it all back on. Shit sucks, bro.

Do some research into compound pharmacies as a worst picture backup. I know several people on them successfully. Peptides can't be patented. Semaglutide is a peptide. They are patenting the delivery mechanism AFAICT. As to sides, ramp up slowly. Maybe you won't have any. Also, there are new drugs coming that are even better. I'm sure the shortages and whatnot will be sorted out. The solution is out there. They can't stop this train.

Re: Ozempic drug supresses desire to smoke, drink and more?

#448

Earlier quoted context omitted.

People like you are the absolute worst to deal with when struggling to lose weight. I managed to lose 150lbs, and it had very little to do with will power, at least the way people like you mean it. I had to reconfigure my entire life around it. I kept barely enough food in the house to meet my calorie target for the week. I once fell asleep while driving home from work and ran off the road because my blood sugar was…

I don't know how you can take a response that says "don't fight the willpower war, just give in and adjust your life so you don't need willpower" and interpret that as the polar opposite of what was written. It is people like you who are the absolute worst to deal with. You take a specific example which probably does not not apply to your body, completely and completely twisted what was said so you can both be a vict…

> I'm 5'11.

> In my early 30s, I was a 31 waist, 170lb, benched a full set of 400lb, ran cross country, and had 6% body fat.

> In my late 30s, I was a 34 waist with high blood pressure.

> I made the change in my diet, and a few years later, I'm a 31 waist, 170lb, normal blood pressure, and 10% bodyfat.

Your enormous transformation was gaining and losing 3 inches on your waist over the course of a decade or so? WOW! Thank you so much for taking the time to share your perspective. That's incredible. Honestly it's amazing to be inspired by someone like you who has been able to manifest such a huge change from exertion of willpower alone. Reminds me of this video: https://www.youtube.com/watch?v=lsSC2vx7zFQ Let me know what you think about it!

They talk about how if you want success, you need to treat it like the air you breathe, that once you want something as bad as you want to breathe, then you'll finally get there.

Huge respect for your personal transformation, and the insane willpower you channeled to lose 3 inches of your waistline over the course of a few years. Being able to drop one whole pant size is simply incredible.

Re: Ozempic drug supresses desire to smoke, drink and more?

#449
post #99

Earlier quoted context omitted.

>>due to the fact that eating now makes her sick. Reminds me of the first FDA approved weight loss drug, Alli, that basically just gastrointestinally punishes you if you eat more than a few grams of fat. https://en.wikipedia.org/wiki/Orlistat#Side_effects

Never trust a fart on orlistat. The horror stories I’ve read of people soiling themselves after eating seemingly normal meals is nuts. On par with Olestra/Haribo sugar-free stories. Also it makes absorbing fat soluble vitamins a huge issue.

The so called Alli-oops.

Re: Ozempic drug supresses desire to smoke, drink and more?

#450

It’s interesting to me how much of the hostility to this drug has a moral dimension. I am quite fit for my middle age. It’s a relative superpower which confers a degree of status in this world. It’s not why I originally became fit 5 or so years ago but it’s something I increasingly notice or to be clear others notice and comment on. I think the “fit” of the world get inherently uncomfortable that our relative social…

Those of us that work out, however, have been dealing with 'cheating with drugs' for a while: steroids. When you get close with enough gym rats, it's utterly shocking how many people with a muscular build use steroids. It's to the point where I essentially don't believe anyone claiming 'natty' (natural) status if they have more than a 1 sigma increase in musculature.

It's also downright laughable how the media/Youtube influencers/etc. treat everyone like idiots. Men's Health will run an article on Mr. Moviestar who was 5'11' and 150 pounds before his role as Superhero Character got to 200 pounds and veiny biceps in 6 months by eating eggs, oatmeal, and chicken breast and doing some situps.

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