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Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

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Re: Ozempic drug supresses desire to smoke, drink and more?

#331

Post by usernew »

vore wrote: post #309
usernew wrote: post #299

Earlier quoted context omitted.

and... this person now takes these last-measure pills forever? or here in the real world, do they use the pills to lose weight, and then maintain that normal weight forever with... perhaps a diet trick that works? people who have to take last-measure medication usually don't stop eating when they are full. i know, it's weird to tell someone who doesn't stop eating when they're full, how to still maintain weight if th…

Obesity is often a chronic medical condition that’s not solely controllable by willpower. There is no difference between taking pills for treating obesity as a chronic condition vs any other chronic condition, like type 1 diabetes. Decades of treating obesity as a personal failing have resulted in worse and unsustainable health outcomes. And again, you are being far too presumptuous about OP’s interventions. And I ce…

>not solely controllable by willpower

so, would you say a solution to the problem that lets you eat as much as you want, so you don't have to use your willpower, be an appropriate solution to suggest? There is a difference between taking last-resort medication for the rest of your life, and eating apples.

Re: Ozempic drug supresses desire to smoke, drink and more?

#332

Post by rblatz »

orhmeh09 wrote: post #279
usernew wrote: post #258

Earlier quoted context omitted.

If you're interested - not pushing an agenda. Here's what worked for this weird dude to not drink and stay fit. I used to lift and be real fit till about 40. Like bulky-lean looking, bench 400 10x with a 6pack. Had a lot to do with being on the road for work all over the world, and you sit at the gym at the hotel for an hour every night because of nothing else to do, and there are girls there also on business who you…

What's your bloodwork and cardio like now and what does your doctor say? No fat + high carbs flies in the face of everything I've read that was published in the last 20 years. Maybe you've found another path to health?

I’ve been a fan of the keto diet (low carb high fat) for a while. But I suspect any diet that cuts a very large group of foods like carbs or fats out forces you to be more mindful of what you’re eating. And that’s a large part of the weight loss on those diets.

Elsewhere in this thread it was stated that food journaling was the gold standard in weight loss, which also I’d expect to increase mindfulness around eating.

Re: Ozempic drug supresses desire to smoke, drink and more?

#333

Post by tempestn »

orhmeh09 wrote: post #279
usernew wrote: post #258

Earlier quoted context omitted.

If you're interested - not pushing an agenda. Here's what worked for this weird dude to not drink and stay fit. I used to lift and be real fit till about 40. Like bulky-lean looking, bench 400 10x with a 6pack. Had a lot to do with being on the road for work all over the world, and you sit at the gym at the hotel for an hour every night because of nothing else to do, and there are girls there also on business who you…

What's your bloodwork and cardio like now and what does your doctor say? No fat + high carbs flies in the face of everything I've read that was published in the last 20 years. Maybe you've found another path to health?

I believe there's a fair bit of evidence to the effect of, any "diet" that restricts one's food options - be it calorie restriction, low fat, low carbs, low protein, intermittent fasting, no sugar, whatever - will result in weight loss as long as it's stuck to. Which makes sense logically; if normally you'd eat whatever you felt like, and then you restrict what (or when) you're "allowed" to eat, some substitution will be done, but you'll likely also just eat less.

And then when you go off the diet (either intentionally, or more likely, by just slowly drifting back to the norm), you'll return to eating what you were before, and will return to your original weight. Which is why the only diet that works is one you can stick to indefinitely. So, if the parent can stick to a no fat, high complex carbs diet for life, it will probably work for them.

Re: Ozempic drug supresses desire to smoke, drink and more?

#334

Post by usernew »

rblatz wrote: post #330
vore wrote: post #309

Earlier quoted context omitted.

Obesity is often a chronic medical condition that’s not solely controllable by willpower. There is no difference between taking pills for treating obesity as a chronic condition vs any other chronic condition, like type 1 diabetes. Decades of treating obesity as a personal failing have resulted in worse and unsustainable health outcomes. And again, you are being far too presumptuous about OP’s interventions. And I ce…

I suspect a chat bot, maybe not got-4, but maybe Bard? It’s close, but there was no point and the references were off but weirdly close. Like florist could be psychiatrist.

I suspect someone who lacks social interaction in life, so does not understand subtle satire. Like a problem that could be solved by a florist. By talking to the florist, making friends with the florist, and having some bbq outings with the florist and her friends on the weekends.

but before one would do that, which may be an insurmountable long-term goal, someone should compare going to a florist for pills, to going to a doctor for making up diets.

Re: Ozempic drug supresses desire to smoke, drink and more?

#335

Post by refurb »

Jun8 wrote: post #178

So, instead is suppressing the desire to eat, how about inventing a drug that blocks the absorption or breakdown of carbohydrates in the gut? Or maybe control the gut biome so that growth of bacteria that breaks down high calorie food is minimized. Is this faster-than-light-like impossible daydream or is there any plausible path to it?

That’s what lactose intolerance is.

Does gas, painful cramping and diarrhea sound like a good approach?

Re: Ozempic drug supresses desire to smoke, drink and more?

#336

Post by rblatz »

remote_phone wrote: post #216
jmpman wrote: post #151

I’ve been on Mounjaro since August. Down almost 60lbs, and it’s been a life changer. Have I had some gastrointestinal issues, sure, but expected. I feel great and my brain seems to be functioning as well as when I was in my 20’s. Now, when I go to the bar with friends, I end up having maybe 2 beers and although enjoyable, I don’t feel that light switch turning on which encourages me to drink more. Can I force myself…

I heard that 2/3 of the weight loss is muscle, do you find that to be the case?

Yeah that was some dude on TikTok selling some diet scam stuff saying that. Or at least that’s where I saw it.

Re: Ozempic drug supresses desire to smoke, drink and more?

#337

Post by rblatz »

pasquinelli wrote: post #245
leroy-is-here wrote: post #229

Earlier quoted context omitted.

Reality does not need to be peer-reviewed to be true.

how could you separate actually will power from the illusion of will power?

I always thought that it’s uncertain if free will exists, but you have to behave as if it does otherwise the world falls into chaos.

Re: Ozempic drug supresses desire to smoke, drink and more?

#339

Post by benrapscallion »

clementmas wrote: post #248

Is this mostly a US drug? I never heard about it in France. I can't believe people love it so much without thinking about the actual source of their problem.

No, it is approved by EMA. https://www.has-sante.fr/jcms/c_2906429/fr/ozempic-semagluti...

Re: Ozempic drug supresses desire to smoke, drink and more?

#340

Post by benrapscallion »

hombre_fatal wrote: post #294
olegious wrote: post #278

Just a heads up “weight loss” is a poor metric if it comes at the cost of lean muscle mass. It seems that 39% of weight loss associated with Ozempic comes from lean muscle mass which isn’t great. https://peterattiamd.com/the-downside-of-glp-1-receptor-agon...

There's no shortage of people debunking that charlatan. https://twitter.com/MichaelAlbertMD/status/16470364172503040...

In 2020, Diabetologia published a body composition analysis of 88 volunteers with type 2 diabetes who used semaglutide for one year. These participants lost an average of 12.5 pounds. Of that weight loss, there was a 7.5-pound reduction in fat mass and a 5-pound reduction in lean mass.

In 2021, a major trial of semaglutide’s weight loss potency examined the body composition of a minority of participants. These patients did not have diabetes, and they took a much larger dose of the drug. The 95 participants to undergo a body scan lost an average of 18 pounds of fat — and 12 pounds of lean mass.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997246/

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