I'm more scared of LSD than ever before, after hearing about that you see "scanlines" for ever after using it. Anyone got this after? https://www.insider.com/9-years-after-acid-trip-man-has-pers...
[deleted]
Effect of LSD on reinforcement learning in humans (2022)
21–30 of 103 posts
Re: Effect of LSD on reinforcement learning in humans (2022)
#22Earlier quoted context omitted.
I'd think there were two ways to produce this. The first would be to not disclose the dose. If you don't know the dose, you might just assume it is a low dose and you aren't getting effects. This is especially easy to pull off since a lot of folks know about microdosing - which usually has the goal of not-too-much-hallucination. Second, you can get folks new to LSD in combination with the above. I'd think that the is…
If you have any hallucinations at all, you're not microdosing. Microdosing is right before the tipping point of recognizing you took something at all. It should be recognizable from long-term effects, not immediately.
Micro dosing (as the name suggests) is more about the input dose, than the output results
Re: Effect of LSD on reinforcement learning in humans (2022)
#23Earlier quoted context omitted.
If you have any hallucinations at all, you're not microdosing. Microdosing is right before the tipping point of recognizing you took something at all. It should be recognizable from long-term effects, not immediately.
I wonder if there is more data about this. A while ago I've microdosed 1 to 2g of fresh truffles(which should not induce a trip), a few days/weeks after a real trip, and I had some hallucinations, which should not have happened IDK, is it possible that a microdose could trigger some kind of a release of a previous buildup of some hallucinogens?
from lots of experience, yes it can
Re: Effect of LSD on reinforcement learning in humans (2022)
#24Earlier quoted context omitted.
If you have any hallucinations at all, you're not microdosing. Microdosing is right before the tipping point of recognizing you took something at all. It should be recognizable from long-term effects, not immediately.
Micro dosing (as the name suggests) is more about the input dose, than the output results
Not really, it is about achieving some effect with a specific dose. The effect is about some improvements in your life without tripping. If you're tripping, you're not microdosing.
Re: Effect of LSD on reinforcement learning in humans (2022)
#25Earlier quoted context omitted.
If you have any hallucinations at all, you're not microdosing. Microdosing is right before the tipping point of recognizing you took something at all. It should be recognizable from long-term effects, not immediately.
I wonder if there is more data about this. A while ago I've microdosed 1 to 2g of fresh truffles(which should not induce a trip), a few days/weeks after a real trip, and I had some hallucinations, which should not have happened IDK, is it possible that a microdose could trigger some kind of a release of a previous buildup of some hallucinogens?
Doses seem to accumulate, that’s why you need days off, too, and they recommend not to mix macro and micro doses. I’ve read somewhere that after a big dose you should wait ~1 month for the effects to wean.
Re: Effect of LSD on reinforcement learning in humans (2022)
#26No expert, but I had some immediate questions when reading this. Wasn't the dose high enough to be easily distinguishable from the placebo without any experience? Why not some other drug a palcebo? Is single blind design actually advisable in such a study? Can someone enlighten me?
I think this would be an issue in any study. I assume the purpose of a double blind is not to convince those in the treatment group they have taken nothing — it’s to convince those in the placebo group they’ve taken something, and then measure that placebo effect.
Re: Effect of LSD on reinforcement learning in humans (2022)
#27Earlier quoted context omitted.
> Wasn't the dose high enough to be easily distinguishable from the placebo without any experience? This was my first thought. There’s no way that anybody would mistake 75 ug of LSD for placebo.
I'm not sure about this. I'm a big guy, I barely feel 100 ug, if I didn't know what LSD was like I could easily not notice
This was intravenous though, so I’d assume the effect to be much stronger than when taken oral.
Re: Effect of LSD on reinforcement learning in humans (2022)
#28It's humorous to me that they bothered injecting saline into the control group here. I'm pretty sure anyone on earth would know whether or not they were on 75 micrograms of LSD, and the act of wondering whether you are or not is enough to induce panic. Pretty sure both groups would produce higher quality data in an unblinded study.
Re: Effect of LSD on reinforcement learning in humans (2022)
#29No expert, but I had some immediate questions when reading this. Wasn't the dose high enough to be easily distinguishable from the placebo without any experience? Why not some other drug a palcebo? Is single blind design actually advisable in such a study? Can someone enlighten me?
> Wasn't the dose high enough to be easily distinguishable from the placebo without any experience? This was my first thought. There’s no way that anybody would mistake 75 ug of LSD for placebo.
The placebo here was saline (no physiological effect). Sometimes they give amphetamines as a placebo so the control group also feel that something is different. But I’d expect that to affect RL hyperparameters too.
Re: Effect of LSD on reinforcement learning in humans (2022)
#30I'm more scared of LSD than ever before, after hearing about that you see "scanlines" for ever after using it. Anyone got this after? https://www.insider.com/9-years-after-acid-trip-man-has-pers...
"My whole mouth went numb" This is a very strong indication for taking NBOME instead of LSD. From the article: "Looking back, I'm pretty certain that what I tried was not LSD." LSD would never numb your mouth. Just Google "LSD mouht numb reddit". Also, there's no lethal does of LSD, NBOM can easily kill you or screw you up just like in the article. Everyone should always test thier substances before taking them to pr…
Yup metallic taste almost certainly NBOME or another RC.
But even so, I didn't have any of these side effects from NBOME, even temporarily. It was just a shorter, more chaotic acid trip with a different kind of visuals and more cohesive consciousness/memory.
I have no regrets about LSD or any other chems I experienced. In fact I credit them with enabling me to finally understand what love is (and isn't).