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New insights into why aspirin works so well

eurekalert.org

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Re: New insights into why aspirin works so well

#41

Post by nobody9999 »

jeffparsons wrote: post #38
drKarl wrote: post #35

When I was a kid aspirin was used for everything, from a headache to fever, etc, now no one uses it anymore, and everyone uses paracetamol and ibuprofen instead...

It's shocking to me how we still refer to paracetamol and ibuprofen in the same breath when their relative risks are so different.

>It's shocking to me how we still refer to paracetamol and ibuprofen in the same breath when their relative risks are so different.

And it's shocking to me how we still refer to paracetamol (Acetominophen for us USAians) and ibuprofen in the same breath, when paracetamol might as well be a sugar pill, for all the good it does and ibuprofen is the liniment of the gods!

Re: New insights into why aspirin works so well

#42

Post by [deleted] »

zabzonk wrote: post #37
glass3 wrote: post #29

Earlier quoted context omitted.

If you haven't seen it: >consumer451 3 months ago | next [–] >I was diagnosed with arthritis at a very young age. [...] >One day I learned about modifying my diet to avoid inflammation. I greatly limited, but did not entirely eliminate, tomatoes and potatoes in my diet. >[...] https://news.ycombinator.com/item?id=34163231

unhappily, i was diagnosed with arthritis at quite an old age (60+) after happily eating tomatoes and tatties for all my life. i won't say what i think about advice like this.

[deleted]

Re: New insights into why aspirin works so well

#43

Post by hoseja »

lispisok wrote: post #2

I've always though Aspirin was a deprecated drug but lately I've heard reports from people who claim it's the only thing that helps their arthritis or other issues. Maybe there is something behind it.

It only seems that way because it's dirt cheap and pharma can't profit off of it very much.

Re: New insights into why aspirin works so well

#44

Post by drKarl »

nobody9999 wrote: post #41
jeffparsons wrote: post #38

Earlier quoted context omitted.

It's shocking to me how we still refer to paracetamol and ibuprofen in the same breath when their relative risks are so different.

>It's shocking to me how we still refer to paracetamol and ibuprofen in the same breath when their relative risks are so different. And it's shocking to me how we still refer to paracetamol (Acetominophen for us USAians) and ibuprofen in the same breath, when paracetamol might as well be a sugar pill, for all the good it does and ibuprofen is the liniment of the gods!

Right, I'm European.

Re: New insights into why aspirin works so well

#45

Post by simianparrot »

nobody9999 wrote: post #41
jeffparsons wrote: post #38

Earlier quoted context omitted.

It's shocking to me how we still refer to paracetamol and ibuprofen in the same breath when their relative risks are so different.

>It's shocking to me how we still refer to paracetamol and ibuprofen in the same breath when their relative risks are so different. And it's shocking to me how we still refer to paracetamol (Acetominophen for us USAians) and ibuprofen in the same breath, when paracetamol might as well be a sugar pill, for all the good it does and ibuprofen is the liniment of the gods!

Ibuprofen being an NSAID is high risk for anyone who’s had stomach ulcers due to its risks involved in causing GI bleeding.

For people like me it’s simply not even an option.

Re: New insights into why aspirin works so well

#46

Post by zabzonk »

archerx wrote: post #39
DoreenMichele wrote: post #28

Earlier quoted context omitted.

They did not ask for health advice from random internet strangers. Trying to bully someone into following medical advice they didn't ask for is not cool.

[flagged]

> how dare the other guy suggest alternatives

that do not work

Re: New insights into why aspirin works so well

#48

Post by wombatpm »

lispisok wrote: post #2

I've always though Aspirin was a deprecated drug but lately I've heard reports from people who claim it's the only thing that helps their arthritis or other issues. Maybe there is something behind it.

Aspirin and other NSAID were supposed to go the way of the dinosaurs. COX2 inhibitors we’re supposed to be the golden child. Too bad it caused kidney and liver damage

Re: New insights into why aspirin works so well

#50

Post by bigDinosaur »

tacroqueen wrote: post #20
cperciva wrote: post #17

Earlier quoted context omitted.

I know a lot of doctors recommend ibuprofen over aspirin because ibuprofen is perceived to be a safer NSAID. I'm not sure if it's actually safer in adults or only in children though.

GI side effects in general and bleeding in particular are higher in analgesic dose level of aspirin. Aspirin is a very blunt instrument - it is both anti-inflammatory and anti-thrombotic - it destroys your platelet function even in low doses - this can be a feature/benefit (ie stroke and coronary artery disease or MI) - but for pure analgesia it usually just means increasing bleeding risk for no benefit.

I don't believe this is a meaningful risk for a healthy person just taking a few aspirin. Certainly you don't want to consume too much (like all medicines) nor use it chronically (unless the alternative risks are worse).
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