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Polio cases in Africa linked to new oral vaccine

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11–20 of 52 posts

Re: Polio cases in Africa linked to new oral vaccine

#11

Earlier quoted context omitted.

I personally believe that those qualities are orthogonal.

Are you saying pharma execs would prefer a working product over a profitable one?

Not the GP, but I'd say that it's easier to overprice an effective product.

Re: Polio cases in Africa linked to new oral vaccine

#12
post #3
post #2

Some amount of vaccine caused polio has for a long time been a problem. The point being made here is that this was a newer polio vaccine which attempted to avoid the risk. It's "vaccine designed to minimise vaccine-caused polio still causes a small number of cases" The second take away is, it's still better than earlier versions of the vaccine. So it could have been "reduced breakout vaccine-caused polio cases in new…

"A problem" is a bit of an understatement... at this point it's basically caused the global polio eradication effort to fail. Wild type 2 poliovirus no longer exists anywhere in the world, and all infections with it over the last couple of decades are vaccine-derived. The original plan was that everywhere would switch to a bivalent oral vaccine without the type 2 virus, any remaining vaccine-derived outbreaks could b…

[deleted]

Re: Polio cases in Africa linked to new oral vaccine

#15

Earlier quoted context omitted.

Are you saying pharma execs would prefer a working product over a profitable one?

Not the GP, but I'd say that it's easier to overprice an effective product.

Recurring revenue vs one time purchase. Not saying this is the case, but we see the obvious attraction to recurring revenue from most software companies.

Re: Polio cases in Africa linked to new oral vaccine

#16
post #14
post #6

In short: A common adverse effect from oral polio vaccine, occurring at a far lower rate in the new vaccine than in the one it replaced. Headline link makes it sound like -bad- news.

[flagged]

I believe you are talking about COVID vaccines wrt to Israel ? Wasn't that mostly because of a new COVID variant surge ?

Re: Polio cases in Africa linked to new oral vaccine

#17
post #16
post #14

Earlier quoted context omitted.

[flagged]

I believe you are talking about COVID vaccines wrt to Israel ? Wasn't that mostly because of a new COVID variant surge ?

Yes, the COVID vaccines is what i am referring to. Well, i don't remember the specifics, but i do remember after that, some other countries started slowly changing route as well.

Actually, a medicine, a vaccine causing the disease it is trying to prevent, is such a strange concept. Imagine hiring someone to keep backup of a database. After some work, installing some programs, and moving some files around, you end up some days later, with a corrupted database and no backup. That person at the start, assures and reassures that everything will go correctly, your database will be safe forever etc. How happy you would be knowing that the person most probably responsible for the corrupted disk, is the expert disk engineer?

Re: Polio cases in Africa linked to new oral vaccine

#19
post #2

Some amount of vaccine caused polio has for a long time been a problem. The point being made here is that this was a newer polio vaccine which attempted to avoid the risk. It's "vaccine designed to minimise vaccine-caused polio still causes a small number of cases" The second take away is, it's still better than earlier versions of the vaccine. So it could have been "reduced breakout vaccine-caused polio cases in new…

Title could start with the word Fewer it seems.

Re: Polio cases in Africa linked to new oral vaccine

#20
post #6

In short: A common adverse effect from oral polio vaccine, occurring at a far lower rate in the new vaccine than in the one it replaced. Headline link makes it sound like -bad- news.

Almost makes it sound like we would have eradicated polio had we not revived with with oral vaccines.
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