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Vitamin D supplementation and incident dementia

alz-journals.onlinelibrary.wiley.com

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Re: Vitamin D supplementation and incident dementia

#101

Post by alfor »

Ezku wrote: post #74

Perhaps not many in this audience are dealing with having to mitigate the prospect of dementia. How about something close to the horizon for almost all of us? > Vitamin D deficiency can cause over‐activation of the pulmonary renin‐angiotensin system (RAS) leading to the respiratory syndrome. RAS is regulated in part at least by angiotensin‐converting enzyme 2 (ACE2), which also acts as a primary receptor for SARS‐CoV…

Infrared is the missing part: https://youtu.be/wadKIiGsDTw Especially for covid, dementia, autoimmune diseases

Re: Vitamin D supplementation and incident dementia

#102

Post by suction »

Aldipower wrote: post #33
fshbbdssbbgdd wrote: post #17

Like all studies into Vitamin D supplementation that aren’t randomized controlled trials, it’s very hard to tell apart cause and effect. Vitamin D naturally occurs when people go outside and get exposed to the sun, and going outside is correlated with all sorts of healthy traits. Also, publicity of the association of vitamin D with good health has led people who care about their health or who have access to good medi…

> Vitamin D naturally occurs when people go outside and get exposed to the sun, ... Not sure where you are living? If I go outside in winter (+2 months around) I need gloves, cap, scarf. Literally only a little portion of my face gets some sunlight until 5pm. Then it is dark! I live in Germany! So, this isn't an argument for a lot of people in cold countries or dark countries. Mostly both.. Exposing to the sun is ver…

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Re: Vitamin D supplementation and incident dementia

#103

Post by suction »

adshouts wrote: post #79
netfortius wrote: post #13

I've been taking 1000 IUs daily, for the last 20 years, skipping summers (during which I would attempt sun exposure), while continuously being within acceptable medians for my age. I sure hope what I am typing now makes sense :-)

I’d get a cold at least once a year and the flu every few years. I started taking 5K IUs of D3 daily in 2019 and haven't had a cold or flu since then.

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Re: Vitamin D supplementation and incident dementia

#104

Post by mgrandl »

spacephysics wrote: post #24

I’ll try to get 15-30 min of sun exposure without sun screen in the warmer months each day. Feel immensely better during then, to a point where I’ve seriously considered moving somewhere warmer without real winter months.

Doesn’t sound like a good idea to forego the sunscreen…

Re: Vitamin D supplementation and incident dementia

#105

Post by moremetadata »

hobo_mark wrote: post #73
moremetadata wrote: post #65

Earlier quoted context omitted.

>Vitamin D naturally occurs when people go outside and get exposed to the sun, and going outside is correlated with all sorts of healthy traits. And also increases the risk of skin cancer and Parkinson's!

You what? Sun gives you Parkinson's now?

If you have limited melanin where does it go, your sun tan or substantia nigra?

Re: Vitamin D supplementation and incident dementia

#106

Post by rowanajmarshall »

adriand wrote: post #56
version_five wrote: post #50

Earlier quoted context omitted.

I had thought that it was possible to get vitamin D from moderate sun exposure in the winter and went looking for info to refute your post. Turns out you are right and I was wrong: https://www.nytimes.com/2022/12/06/well/live/vitamin-d-defic... People living above the 37th parallel, basically the tropics, may not be getting enough in the winter, because the sun isn't strong enough to provide it.

It’s brutal, I live near Toronto and not only is the winter sun quite weak but sunny days are quite uncommon. Almost every day is grey and overcast. Combine that with short daylight periods and winter becomes quite the gruelling challenge in terms of mental health especially.

And even then, Toronto gets about 2000 hours of annual sunshine, while London (a D swathes of Northern Europe) get about 1600 hours :(

Re: Vitamin D supplementation and incident dementia

#107

Post by codethief »

Rury wrote: post #77
version_five wrote: post #50

Earlier quoted context omitted.

I had thought that it was possible to get vitamin D from moderate sun exposure in the winter and went looking for info to refute your post. Turns out you are right and I was wrong: https://www.nytimes.com/2022/12/06/well/live/vitamin-d-defic... People living above the 37th parallel, basically the tropics, may not be getting enough in the winter, because the sun isn't strong enough to provide it.

Yes, this is the reason people further from the tropics tend to have lighter skin and are more likely to have genetics allowing for lactose tolerance throughout life. They're natural adaptations by the body, in response to being in an environment which sunlight (and therefore vitamin D) is more scarce.

So you're saying darker skin prevents the body from producing vitamin D? (Not saying it doesn't, I just didn't know.)

Also, what does lactose (in-)tolerance have to do with… anything? To my knowledge, the fact that lactose tolerance is that common among Europeans is largely a result of thousands of years of domesticating dairy animals. Not all light-skinned people in the world are automatically lactose-tolerant (or "are more likely to have genetics allowing for lactose tolerance throughout life" as you say).

Wikipedia agrees:

> Lactase persistence evolved in several populations independently, probably as an adaptation to the domestication of dairy animals around 10,000 years ago. Today the prevalence of lactose tolerance varies widely between regions and ethnic groups. The ability to digest lactose is most common in people of European descent, and to a lesser extent in some parts of the Middle East and Africa.

https://en.m.wikipedia.org/wiki/Lactose_intolerance

Also see the map on https://en.m.wikipedia.org/wiki/Lactase_persistence .

Re: Vitamin D supplementation and incident dementia

#108

Post by agsnu »

adshouts wrote: post #79
netfortius wrote: post #13

I've been taking 1000 IUs daily, for the last 20 years, skipping summers (during which I would attempt sun exposure), while continuously being within acceptable medians for my age. I sure hope what I am typing now makes sense :-)

I’d get a cold at least once a year and the flu every few years. I started taking 5K IUs of D3 daily in 2019 and haven't had a cold or flu since then.

Flu spread among all humans (not just those supplementing vit D) was massively reduced in recent years because of a little thing called COVID-19 and all the social distancing/lockdowns that led to...

Re: Vitamin D supplementation and incident dementia

#109

Post by codethief »

iopq wrote: post #78
_yb2s wrote: post #71

Earlier quoted context omitted.

Our bodies can store enough to make it through the winter if you are replete at the beginning.

That, of course, assumes you don't wear sunscreen during the summer/fall, which I do

You might enjoy this article:

https://www.outsideonline.com/health/wellness/sunscreen-sun-...

Re: Vitamin D supplementation and incident dementia

#110

Post by spirit557 »

DarknessFalls wrote: post #95
spirit557 wrote: post #86

Earlier quoted context omitted.

Id suggest you get a couple vitamin d tests in different seasons and also consider your latitude. i was taking about 4000iu + natural sources in the winter and i still tested low and had to increase my intake. If you dont test you're sorta just guessing. take with meal or fats. cramps could also be from low potassium. my natural sources i use are - whole fat yogurt - pastured eggs (way higher in vit. d than grain fed…

How much K2 do you take? 100mg? And do you vary the time of day that you take it?

ill take 100mcg mk7 + i eat mild kimchi once a day which is also a source. as for timing i just take after my meal. i eat one meal a day or two meals a day (and zero snacks), but my timing of those meals always varies a lot but it's always after ive had my fats and proteins during my meal.

i am (was?) someone who gets plaque build up in their teeth quickly if i dont brush morning and night every day. once i started k2 that completely stopped. i was shocked at the difference. of course i stil brush in morning and after my last meal but the feeling in my teeth of plaque building up just vanished with daily k2.

i use the now foods brand, its not expensive and I think its made from commercially grown natto. you should not have to pay more than around $10-15 for one month supply.

this cardiologist has a nice short lecture on k2 that really opened my eyes to it. https://www.youtube.com/watch?v=z3njgh2nFRk - he recommmends 200mcg per day

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