Loss of religious grounding.
Christianity was the north star for our societies, it organized people, align them to work together, put the future(love) before personal interest(excess pleasures, sins)
Without religion we are going to fail. There never was a working society without religion. Yes we are in a different time, we have to update our stories, but if we throw them out we are going to collapse.
Ex: does a doctor does what is good for him or for his patient? What about a regulator in the government or a scientific working at Pfizer, Twitter a bank or Google?
If people stop putting truth and love on top(christianity) and put personal gain higher not much of what we have will keep on working for long.
Personal side: we have never been more materialy comfortable yet we are more depressed, more anxious, more medicamented.
Family: We no longer have enough kids or manage to keep a couple long enough to bring kids into adulthood. Kids to single parent household do worse in almost every metric yet we don’t care or don’t look.
On the flip side a lot of people are looking for the missing pieces, are trying to reintegrate the wisdom that we had in an modern framework: Jordan Peterson, Verdake, Jonathan Pageau and others.
It’s very hard to reverse. If people no longer believe to higher power (truth and love) we default to a lower version of ourselves, our animals instincts and we don’t know how low we will go: should successful men have only one woman? Why not? People are free to do whatever they want. Could a billionaire have a huge harem of thousand of women ala Genghis Khan? If not, why not?
There is no rules anymore (beside obvious immediate harm). We have discarded our ancient wisdom as useless, so we create all the harms that are on a longer timescale: trust, family, society.