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Making chloroform so I can sleep better at night [video]

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Re: Making chloroform so I can sleep better at night [video]

#101

Post by girvo »

ok_computer wrote: post #92
gus_massa wrote: post #2

The author is Chemdelic. I was expecting a video by Nile Red, but I was not disappointed. (As the video explain, don't try this at home unless you have a degree in Chemistry or something. That invisible fumes looks nasty.)

Even doing this with a chemistry background is incredibly irresponsible. There’s more than personal know how at work in industrial and academic labs. Fume hood stacks well above grade and incinerators and permits or registration. Plus the waste disposal issue and byproducts. This brand of youtube entertainment is super bad. Same thing with people extracting mercury or whatever. Like what is the best end case: you’ve…

> Chlorinated solvents are no joke

I mean, you're right, but I can also literally walk down to Bunnings and buy some, so I'm not sure these YouTubers are really tipping the scales.

Re: Making chloroform so I can sleep better at night [video]

#102

Post by andrewflnr »

post-it wrote: post #89
fragmede wrote: post #81

Earlier quoted context omitted.

Why is the O in N₂O not accessible, thus resulting in hypoxia? If you blow nitrous oxide through a lit cigarette the resulting increased burn it says there's more oxygen, not a lack of it.

Same reason the O in CO2 isn't accessible. Oxygen is used as an oxidizer in the slow burn that is human respiration. N2O is already "burnt", so your body can't burn it any further to release energy.

That contradicts "nitrous is an oxidant". Or at minimum, makes it more complicated.

Re: Making chloroform so I can sleep better at night [video]

#104

Post by cwkoss »

post-it wrote: post #89
fragmede wrote: post #81

Earlier quoted context omitted.

Why is the O in N₂O not accessible, thus resulting in hypoxia? If you blow nitrous oxide through a lit cigarette the resulting increased burn it says there's more oxygen, not a lack of it.

Same reason the O in CO2 isn't accessible. Oxygen is used as an oxidizer in the slow burn that is human respiration. N2O is already "burnt", so your body can't burn it any further to release energy.

I believe nitrous oxide can act as an oxidizer, but cannot be used for respiration for a different reason than CO2 (already fully oxidized). But I'm not sure what that reason is: maybe the enzymatic capacity to pull the O off the N2 is just order(s) of magnitude too small or it has to go through NO metabolism.

Re: Making chloroform so I can sleep better at night [video]

#105

Post by toss1 »

jefftk wrote: post #94
toss1 wrote: post #82

Earlier quoted context omitted.

Yup, similar to frostbite. Normal skin temp is around 86°F. as it is cooled, it goes from cool to cold sensation, to very painful at around 55°F. Below that, you don't feel anything as it continues to cool to the point where it freezes solid (which wouldn't be a problem if the freeze-thaw cycle didn't create so many little spiny ice structures that break the cell walls; a type of frog has 'anti-freeze' in it's makeup…

> a type of frog has 'anti-freeze' in it's makeup so it can freeze and re-thaw Nit: it can't actually recover from freezing solid. It just has lowered the freezing point of the remaining liquid to below the temperatures it's going to encounter.

Thanks, you provoked me to look it up in more detail, and we're both oversimplifying, and it's even wilder than I thought. From [0]:

>> On an organismal level, they are completely frozen to death — their heart stops beating and breathing ceases. Image via Facebook

>> The frog’s death-defying trick actually comes down to one simple factor: nucleating proteins. When the frog’s skin begins to freeze, these proteins cause the water within the frog’s blood to freeze first, which in turn serves as a vacuum for most of the water out of the cells. Simultaneously, their bodies pump out large amounts of glucose to serve as stuffing material, which prevents the cells from collapsing.

>> Essentially, frogs fill their bodies full of sugar to keep themselves alive through winter. When warm temperatures melt the snow around their hibernacula, frogs slowly thaw back to life. Water melts and returns to the bloodstream, begins circulating, and restarts their heart and breathing. Within an hour or so the frog returns to normal life, completely unscathed.

Just wild!

[0] https://roaring.earth/frogs-literally-freeze-during-winter-a...

Re: Making chloroform so I can sleep better at night [video]

#106

Post by sterlind »

azalemeth wrote: post #93
kortex wrote: post #79

Earlier quoted context omitted.

> The poor efficacy of DMSO in assisting drug translocation through skin Oh yeah, for the observer gallery: The reason DMSO (and DMF, DMAc, HF, to an extent haloforms, and polar aprotic solvents in general) are dangerous is that they can dissolve and transport small molecules (under 1000 daltons, possibly more) through your skin and into the bloodstream. They go straight through nitrile, vinyl, and latex gloves. You…

The garlic like smell of DMSO just doesn't leave you if it gets into your skin. It's "safe" but really, really bad to have fingertips smelling of it for days. I wish I had those bovine gloves during my PhD...

isn't DMSO used as a (home?) remedy for joint pain?

I've thought about trying it but have visions of it leaching the dye from my clothing and transporting it into my bloodstream. the garlic wouldn't make me many friends, but dissolving poisons is scarier.

Re: Making chloroform so I can sleep better at night [video]

#107

Post by ok_computer »

girvo wrote: post #101
ok_computer wrote: post #92

Earlier quoted context omitted.

Even doing this with a chemistry background is incredibly irresponsible. There’s more than personal know how at work in industrial and academic labs. Fume hood stacks well above grade and incinerators and permits or registration. Plus the waste disposal issue and byproducts. This brand of youtube entertainment is super bad. Same thing with people extracting mercury or whatever. Like what is the best end case: you’ve…

> Chlorinated solvents are no joke I mean, you're right, but I can also literally walk down to Bunnings and buy some, so I'm not sure these YouTubers are really tipping the scales.

I'm not offended by the volume he's producing, just the act of doing low value chemistry work at home making something gross, it will get repeated by less capable viewers in uncontrolled environments.

On the other hand, I always thought things like anarchist cookbook and erowid type stuff is great for knowledge sharing. I don't think there should be a monopoly on knowing how to do stuff but this is different, maybe the youtube viewership monetization, I cannot place my finger on it.

I'm saying this is a dumb synthesis to show off, there is no value in the product, if anything it is a disposal liability, and it's in a home lab. One mistake and you get a chlorine cloud or an organic solvent spill in a residential setting.

It glorifies understanding where the electrons or protons jump but its super basic. Like how hungry for validation do you need to be to show off your recent degree or internet recipe scavenging.

Solvents are commoditized. Chlorinated solvents need to be phased out. Whereas, in industrial settings that are vilified for justifiable reasons there is increasing scrutiny on any solvents introduction to processes especially chlorinated types for good reason.

I'm saying it's a dumb thing to do and totally misses the mark for educational videos.

That guy who makes chips in his garage with nasty etch gasses, high voltage magnatrons, photoresist, and projector litho I'll admit is really cool and impressive but may pose a greater neighbor threat if a mishap happens.

Re: Making chloroform so I can sleep better at night [video]

#108

Post by sterlind »

labrador wrote: post #17

I'm a recovering nitrous oxide addict so this is interesting, but people should proceed with caution. I didn't know laughing gas could be addictive for some people until it was too late. In the film Cider House Rules, Michael Caine plays a doctor addicted to ether for sleep https://en.wikipedia.org/wiki/The_Cider_House_Rules_(film) Google result: Is chloroform stronger than ether? Fluothane and chloroform produced si…

I'm sure you know but PSA for those that don't: N2O is practically the only "safe" inhalant. Others, like gasoline, computer duster, urinal pucks, etc. have a risk of causing spontaneous heart attacks even in young healthy users.

N2O's main physical risk is B12 deficiency, or asphyxiating if you use a mask.

Re: Making chloroform so I can sleep better at night [video]

#109

Post by giraffe_lady »

siliconunit wrote: post #75
labrador wrote: post #17

I'm a recovering nitrous oxide addict so this is interesting, but people should proceed with caution. I didn't know laughing gas could be addictive for some people until it was too late. In the film Cider House Rules, Michael Caine plays a doctor addicted to ether for sleep https://en.wikipedia.org/wiki/The_Cider_House_Rules_(film) Google result: Is chloroform stronger than ether? Fluothane and chloroform produced si…

[flagged]

Yeah and I've done heroin and cocaine plenty of times without getting addicted but those are notoriously dangerous things to play with. Didn't help me out any with alcohol and I spent decades fighting that one off. Why risk it why encourage people to why even write this here?

Re: Making chloroform so I can sleep better at night [video]

#110

Post by girvo »

ok_computer wrote: post #107
girvo wrote: post #101

Earlier quoted context omitted.

> Chlorinated solvents are no joke I mean, you're right, but I can also literally walk down to Bunnings and buy some, so I'm not sure these YouTubers are really tipping the scales.

I'm not offended by the volume he's producing, just the act of doing low value chemistry work at home making something gross, it will get repeated by less capable viewers in uncontrolled environments. On the other hand, I always thought things like anarchist cookbook and erowid type stuff is great for knowledge sharing. I don't think there should be a monopoly on knowing how to do stuff but this is different, maybe t…

> …it will get repeated by less capable viewers in uncontrolled environments.

Maybe.

I dunno, I’ve been active in underground chemistry forums for 15 years at this point, and the thing it drove home to me is that 99.9% of the people on there are armchair chemists, and only a tiny fraction actually do any home chemistry.

It’s all exciting to read about and watch, but for the most part people steer clear (for sane, good reasons). I can’t imagine this will be any different, same with NileRed, same with Explosions and Fire.

Agreed on the need to phase out chlorinated solvents, but again I’m much more worried about Joe Blow buying DCM paint stripper from the hardware store and not understand what it is than I am someone who does know what it is watching someone else synthesise chloroform.

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