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Making chloroform so I can sleep better at night [video]

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Re: Making chloroform so I can sleep better at night [video]

#81

Post by fragmede »

labrador wrote: post #52
cwkoss wrote: post #49

Earlier quoted context omitted.

Did you have any issues with B12 deficiency? I've always wondered to what extent oral B12 supplementation can mitigate the health risks of chronic nitrous use.

Yes I need to take B-12 liquid orally or by shot, but my grandfather had pernicious anemia and it's hereditary, so I don't know whose fault it is. Other than that I have no major health problems, but I have neuropathic nerve pains that the doctor has never seen before so he blames the nitrous. It's not too bad. I was aware that I needed to take a lot of B-12 at the time. People ask me why I didn't get a tank instead…

Why is the O in N₂O not accessible, thus resulting in hypoxia? If you blow nitrous oxide through a lit cigarette the resulting increased burn it says there's more oxygen, not a lack of it.

Re: Making chloroform so I can sleep better at night [video]

#82

Post by toss1 »

joosters wrote: post #51
kortex wrote: post #23

Earlier quoted context omitted.

> Join us for our continued lecture series, covering topics such as Please share/blog these! I too have several degenerate chemistry undergrad stories. > The poor efficacy of DMSO in assisting drug translocation through skin Yep. During one particularly sleep-deprived finals week, and after recently learning about DMSO's transdermal transportation abilities, my friend and I tried making caffeine skin patches. It work…

But my lab manager did walk in at one point and immediately recoiled from the fumes (which we were nose-deaf to at that point). I don't know whether it's true or not, but I remember a chemistry lecturer telling me that you don't need to worry about terrible smells in the lab, our noses are sensitive to extremely miniscule levels of chemicals. It's when the levels are so high that they have overpowered our senses and…

Yup, similar to frostbite. Normal skin temp is around 86°F. as it is cooled, it goes from cool to cold sensation, to very painful at around 55°F. Below that, you don't feel anything as it continues to cool to the point where it freezes solid (which wouldn't be a problem if the freeze-thaw cycle didn't create so many little spiny ice structures that break the cell walls; a type of frog has 'anti-freeze' in it's makeup so it can freeze and re-thaw). So, when your skin stops being painful, that's when you really need to warm it up NOW.

Re: Making chloroform so I can sleep better at night [video]

#83

Post by kortex »

petre wrote: post #35
gus_massa wrote: post #2

The author is Chemdelic. I was expecting a video by Nile Red, but I was not disappointed. (As the video explain, don't try this at home unless you have a degree in Chemistry or something. That invisible fumes looks nasty.)

Definitely do not try this at home without a Chemistry degree. Why? It's easy to accidentaly produce phosgene (WWI chemical weapon, smells like freshly cut grass) by combining chloroform fumes and oxygen under UV light or chlorine with carbon monoxide from a gas burner (yellow flame).

Actual chemist here: it's actually pretty hard to accidentally produce phosgene via chloroform. Obviously don't deliberately try to oxidize chloroform in an unventilated space, but you should be fine in a fume cupboard with basic science hygiene.

Don't attempt this without an understanding of general lab/workshop hygiene (ALWAYS wear glasses, gloves, labcoat or smock, no polyester, use proper ventilation, put hair back). But this is a pretty basic beginner chemistry experiment.

Re: Making chloroform so I can sleep better at night [video]

#84

Post by frakt0x90 »

cwkoss wrote: post #44

Is there a youtube channel all about how chemical waste is neutralized for disposal? What happens to the tub of very basic water and maybe some bleach? Just pour down the drain? What pHs are safe to pour down the drain? How is more complex waste, like containing pharmacological products or heavy metals, neutralized and disposed?

NileBlue (NileRed's second channel) has a view videos on cleanup of various substances.

https://www.youtube.com/@NileBlue/videos

Re: Making chloroform so I can sleep better at night [video]

#85

Post by at_a_remove »

xkcd-sucks wrote: post #18

Chloroform is great for extractions (if you don't care about the environment) because it sinks to the bottom of a sep funnel, but the thing about it being a knockout gas or sleep aid is complete BS. Based on an unpublished study of about 4 degenerate chemistry undergrads: - It PROBABLY takes several minutes of inhalation through a saturated rag to induce full loss of consciousness, although shorter times do produce n…

That's why the primitive anesthetic ACE (Alcohol, Chloroform, Ether) existed in many proportions, but never chloroform alone.

Re: Making chloroform so I can sleep better at night [video]

#86

Post by giantg2 »

xkcd-sucks wrote: post #18

Chloroform is great for extractions (if you don't care about the environment) because it sinks to the bottom of a sep funnel, but the thing about it being a knockout gas or sleep aid is complete BS. Based on an unpublished study of about 4 degenerate chemistry undergrads: - It PROBABLY takes several minutes of inhalation through a saturated rag to induce full loss of consciousness, although shorter times do produce n…

The biggest issue is that it poses health risks, like being carcinogenic.

Re: Making chloroform so I can sleep better at night [video]

#87

Post by labrador »

JKCalhoun wrote: post #76
labrador wrote: post #48

Earlier quoted context omitted.

Let's see there's 50 whippets in a box, 12 boxes in a case. I did a couple hundred cases before I finally stopped. My last two binges 5 years apart were 15 cases over a 2 week period and 20 cases over a 10 day period. Once I start cracking whippets I can't stop. It felt almost like an OCD thing.

* whip-its

The European manufacturers I used spell it a variety of ways

Re: Making chloroform so I can sleep better at night [video]

#88

Post by giantg2 »

kortex wrote: post #29
occamrazor wrote: post #24

Earlier quoted context omitted.

I remember reading (can’t find the source anymore) that ether would work as knock-out drug, and that indeed it was used as a plot device in crime books as chloroform is used in movies today. The problem is that ether can be highly toxic at relatively low dosage, and then it was replaced by chloroform in fiction to avoid giving dangerous ideas to people. Is there any truth behind this theory?

Ether and chloroform both have relatively narrow therapeutic windows - the toxic dose is very close to the minimum active dose. But they were one of the few true anaesthetics at the time (late 1800s). Alcohol was also used for surgery but it's slower and inhibits clotting. In fact often it'd be a combination of all three, known as ACE [1]. This worked okay-ish, as the GABA-ergic synergy was able to suppress conscious…

I've heard that grayanotoxin was uses for surgery around that time frame as well.

Re: Making chloroform so I can sleep better at night [video]

#89

Post by post-it »

fragmede wrote: post #81
labrador wrote: post #52

Earlier quoted context omitted.

Yes I need to take B-12 liquid orally or by shot, but my grandfather had pernicious anemia and it's hereditary, so I don't know whose fault it is. Other than that I have no major health problems, but I have neuropathic nerve pains that the doctor has never seen before so he blames the nitrous. It's not too bad. I was aware that I needed to take a lot of B-12 at the time. People ask me why I didn't get a tank instead…

Why is the O in N₂O not accessible, thus resulting in hypoxia? If you blow nitrous oxide through a lit cigarette the resulting increased burn it says there's more oxygen, not a lack of it.

Same reason the O in CO2 isn't accessible. Oxygen is used as an oxidizer in the slow burn that is human respiration. N2O is already "burnt", so your body can't burn it any further to release energy.

Re: Making chloroform so I can sleep better at night [video]

#90

Post by schwartzworld »

labrador wrote: post #48
hattmall wrote: post #42

Earlier quoted context omitted.

So like how much nitrous did you do?

Let's see there's 50 whippets in a box, 12 boxes in a case. I did a couple hundred cases before I finally stopped. My last two binges 5 years apart were 15 cases over a 2 week period and 20 cases over a 10 day period. Once I start cracking whippets I can't stop. It felt almost like an OCD thing.

It's called hippie crack for a reason.
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