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Aerobic exercise can reduce the risk of metastatic cancer in mice: study

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Re: Aerobic exercise can reduce the risk of metastatic cancer in mice: study

#91
post #88

I get mixed feelings whenever I see one of these reports. It's nice to get more data in the fight against cancer but it doesn't look like any progress in directly attacking cancer. And there's doubt about the data too. I wonder about how much money and effort is going into such studies which is not being invested into novel techniques for attacking cancer.

I consider it a weak form of Pascal's wager.

You could do cardiovascular exercise which, in theory, might possibly have a beneficial reduction in personal cancer rates (among many other potential health benefits attributed to persistent exercise). Or you could not do cardio.

Seems like a no-brainer for most people.

Re: Aerobic exercise can reduce the risk of metastatic cancer in mice: study

#92
post #12

I know of so many life-long runners that have gotten or even died from cancer. So not sure what to say otherwise but this paper is wrong and needs to be challanged.

Anecdotal, but related: https://seema.page/

Related HN discussion: https://news.ycombinator.com/item?id=30597187

Re: Aerobic exercise can reduce the risk of metastatic cancer in mice: study

#94

IN MICE link to full paper: https://aacrjournals.org/cancerres/article/82/22/4164/710131...

isn't the point that mice and humans implement many of the same (pertinent) traits, in programming language terms, with regard to this topic, though?

Re: Aerobic exercise can reduce the risk of metastatic cancer in mice: study

#97
post #72
post #12

I know of so many life-long runners that have gotten or even died from cancer. So not sure what to say otherwise but this paper is wrong and needs to be challanged.

anybody who lives long enough succumbs to cancer. anybody. not one exception. you can have the fittest heart and safest lifestyle, but your cells will always replicate with less and less accuracy, the sun and other sources of genetic damage will keep inundating you.

Yeah, I wouldn't be surprised if more runners do die from cancer. Because they're not falling victim to all the other things that are improved by cardio fitness, etc.

Re: Aerobic exercise can reduce the risk of metastatic cancer in mice: study

#98

IN MICE link to full paper: https://aacrjournals.org/cancerres/article/82/22/4164/710131...

Title inmiced and bestudied. First time I got to do both!

Edit: oops

https://news.ycombinator.com/item?id=30456358

https://news.ycombinator.com/item?id=27756721

https://news.ycombinator.com/item?id=21605643

etc.

Re: Aerobic exercise can reduce the risk of metastatic cancer in mice: study

#99
post #67

Earlier quoted context omitted.

I have a few opinions about distance running. A coworker explained it has a way of turning down the volume on the rest of your perception. Something about running 10 miles makes other problems less anxiety inducing. They're still important, they're just not, like, scary. If you consider distance running, get good shoes. go to the kind of place that puts you in shoes, and videos you running on a treadmill. Some people…

I completely agree on all of this. I had an on again off again relationship with running before this year and it’s because… I ran in the same shoes for 8 years and I’d stop when my hip or knee felt off. Got new shoes this year and I’ve done more running than I ever had with no issues. Shoes only last 250-500 miles! Definitely agree with pain as well, there is good pain and bad pain and tendon pain is never good pain.

Another voice for replacing shoes regularly. Don't try to stretch their lifetime out too far -- you'll pay for it in pain and injury.

Re: Aerobic exercise can reduce the risk of metastatic cancer in mice: study

#100
post #61
post #48

Earlier quoted context omitted.

Have you actually tested your max heart rate? I work out with a HRM for Zone 2, but I'm just going off of Polar's zones. From what I understand going more in depth requires either maxing out your HR (Steve House describes how you can do this in Training for the New Alpinism - basically sprinting uphill until you collapse, seems really unpleasant) or doing lactate testing in a lab.

You can easily test relatively accurate max heart rate just by running a 5K race. Run a slightly slower than race pace, and go as hard as you can at the very end (last 1K) with the goal of sprinting to the finish line and vomit. It's unpleasant, but relatively safe during a race event with medical staff there at the end. Also, max heart rate is only useful after you've been running for awhile. If your body hasn't sta…

> Also, max heart rate is only useful after you've been running for awhile

100%, don’t geek out in the beginning just run at a slow pace until it’s comfortable and several consistent months in tinker around

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