Ever hear of JA Konrath? Neither did I at first. He's, at best, a mid-to-back list writer who had a few novels published back in the late 90s and early 2000s. He started self-publishing his old catalog of books once they were reverted (ie, the publishers saw little/no value in holding the rights, and released the rights back to him). He saw not much in the way of sales, but he pressed on, releasing ebook forms of old and new novels as he published them.
Then, the Kindle.
As of today, every new title he releases goes straight into the Amazon top 100 list. Every single new one. And, he's not alone.
Amanda Hocking, John Locke, Michael Sullivan and hundreds of other new and established writers, some who have zero published work or professional experience have made substantial living self-publishing, mostly in DRM-free epub and mobi formats. None of them are running experiments in digital distribution or DRM that I know of.
It's a proven method: For apps, for ebooks, for video (ie Louis CK for paid video and Ryan Higa, Freddie Wong, or Ray William Johnson for ad-supported video). We read (some with disdain, I might add) when someone publishes an ebook through ejunkie that sells a tens of thousands of copies at US$30 a pop, yet we don't question whether that's some "experiment" or not.
It's the future. We'll all have to embrace it eventually.