I recently switched from a 4k monitor+one/two 1080p monitors to a single monitor, and I prefer it now as well, but with one big caveat - it is a single 5k ultrawide monitor with thunderbolt 4. I simply connect my macbook to it using one cable, and I am done. That one cable provides power/charge to the laptop, outputs stuff on my big screen, and allows my laptop to use any devices connected to the USB hub built into the monitor. Zero fiddling around or setup required (aside from the physical space), and no bajillion cables requiring me to worry about managing them (as long as I want to keep my workspace neat and clean, which I do).
Even doing a single regular 4k monitor was stretching it for me, but my current setup satisfies me almost perfectly. The only upgrade I am planning to do in that aspect in the future is replacing it with an AR/VR headset that can emulate screens at a good enough resolution. While the current VR/AR tech isn't there yet, it is getting closer and closer, which gives me a lot of hope. I tried Quest 2 for that purpose, and I would pick it over a dual 1080p monitor setup even now. Sadly, it isn't quite as good as a single 5k ultrawide at the moment. There are other (very solvable) rought points with it currently too, like comfort (Quest 2 gets a bit tiring and sweaty to use after a couple of hours), but I heard Quest Pro has addressed that specific one, which is also awesome to see.
Given the leaps I've observed over the past few years, I feel like people are realizing the immense value of it, and the companies realize it too. So I am expecting something like this to be a fully viable solution for me within the next 5 years. And that's not even going into the portability aspect. As someone working from a hotel for the past 2 weeks, it would be amazing to have an AR/VR headset that would allow me to have the same setup everywhere, because I am not going to lug my 5k ultrawide with me wherever I need to work. Which is also why I prefer to work from home rather than the office, because my current home setup is much more optimal for my productivity that my office one.