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Accelerated forgetting of a trauma event after a single dose of hydrocortisone

nature.com

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Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#91

Why is stress after trauma a 'disorder'? And how is it a solution to drug people up, making them forget this?

That's a bit like asking "why is pain after an injury a 'disorder'"? Just like some people are left with persistent recurrent pain in an otherwise healthy and recovered limb (often known as rheumatism), some people are left with persistent recurrent stress after trauma - such as suddenly bursting out crying or cowering in fear after incidentally remembering trauma that happened 20 years ago while doing the dishes. Wh…

I don't consider any kind of acute pain acceptable personally. Even if short-lived. Unless it's needed as a signal to pull your hand out of a fire or something.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#92

I dont think that this approach is a good idea at all. Our brains are complex entities, this treats it as a simple one. I think it will leave a hole in continuity and it may well be helpful, but residual awareness that something horrible has occurred will linger and it will be harder to resolve. I guess what I am trying to say is that the body remembers, even if we manage to pluck out one simple way the body goes abo…

I am entirely in agreement with you. That said, humanity has never been a defense against atrocities. If anything, it is the opposite. Humanity has for as long as I've learned history been gleefully and willingly committing atrocities in war. This is a rule, not an exception.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#93

Combine with propranolol for maximum effect. A very overlooked drug that can be used in the treatment of many disorders related to anxiety, stress and fear. Without the risk of debiliating addiction benzos and benzolikes bring. https://pubmed.ncbi.nlm.nih.gov/14573324/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692719/

> propranolol [for] anxiety, stress and fear I recall reading that propranolol reduces the physical manifestations of anxiety, stress and fear, but you still feel it internally. For example, when used for stage fright, you won't fidget, stutter, blush, sweat, and have a racing heart beat, but you'll still feel the anxiety inside yourself.

What is anxiety except those physical manifestations and how hard they make it to think?

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#94

Earlier quoted context omitted.

GPT3 is that good. Sign up and try it for yourself. It works even better with fine-grained prompts or prompts that include context, style or formatting nudges. It writes better than me with a little help.

Wow, thank you for that advice/warning. I didn't expect I could be fooled by GPT3. At some point in the future, yes, but not today. But I guess the time has come.

GPT type bots have been writing news articles for close on to a decade. With a little light editing they're indistinguishable.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#95

I dont think that this approach is a good idea at all. Our brains are complex entities, this treats it as a simple one. I think it will leave a hole in continuity and it may well be helpful, but residual awareness that something horrible has occurred will linger and it will be harder to resolve. I guess what I am trying to say is that the body remembers, even if we manage to pluck out one simple way the body goes abo…

I made a very deep PTSD syndrome once... The kind which get you homeless in matters of months.

I was having non-stop flashback of traumatic events... When I was deep in these memories(what i think they call intrusion), It was like having taken cocaine with 10e5 effect flooding my frontal lobe, a lot of anger and depression at the same time. I was enable to get out of bed except once in a week to buy some food... When I ran out of food I could stay +48h without anyintake...

I googled something about memory improvement or trauma... I don't remember well... and came to read about an hormone, sold in most dieterary shop on the internet. I decided to give it a try.

It was life saving. Instant effects. In a month of self prescribed cure, I was coming back to life. It had unfortunately a few side effect, the most dominant was burst of anger. So I stopped it. But it was enough to get me in track.

What would have been the alternative solution ? Therapy ? Which one? Most of them (if not all) are either pseudo-science gibberich when it is not plain mystical or "spiritual" bullocks, like the one that says you want to fuck your mother but you don't know it until you spend 7 years, 100$/week, on a couch telling whatever come to your mind to a guy which could as well be emulated by an 60's version of therapist bot.

I'm not sure the product I ordered was what was advertised. Years latters, I ordered it again (an other brand) and it had no the same effect if any at all.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#96

I dont think that this approach is a good idea at all. Our brains are complex entities, this treats it as a simple one. I think it will leave a hole in continuity and it may well be helpful, but residual awareness that something horrible has occurred will linger and it will be harder to resolve. I guess what I am trying to say is that the body remembers, even if we manage to pluck out one simple way the body goes abo…

That’s like saying “people should put in the hard work of working through depression rather than relying on medication”.

What could be the rationale for denying someone an effective treatment?

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#97
post #87
post #86

Earlier quoted context omitted.

This is true, but only because the brain is a part of the body. The brain remembers things.

That neglects all the other ecosystems in your body that lead you to behave the way you do. Have you ever been hangry? How about the experience of chronic intestinal irritation worsening your depression? How do you feel in your head when you can’t stop your heart from racing after a stressful day of work? Those are all examples of the inverse.

Those are all examples of the brains response.

The body is the trigger but the brain is the source of the symptoms.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#98

Earlier quoted context omitted.

That's a bit like asking "why is pain after an injury a 'disorder'"? Just like some people are left with persistent recurrent pain in an otherwise healthy and recovered limb (often known as rheumatism), some people are left with persistent recurrent stress after trauma - such as suddenly bursting out crying or cowering in fear after incidentally remembering trauma that happened 20 years ago while doing the dishes. Wh…

I don't consider any kind of acute pain acceptable personally. Even if short-lived. Unless it's needed as a signal to pull your hand out of a fire or something.

If you didn't feel pain while having an injury, you'd quickly find that you are extremely likely to greatly aggravate that injury (e.g. walking with a broken bone in your foot is possible, but it hurts terribly to help you not do it, sine it will ruin the bone and any chance of ever recovering).

We know this for sure since there is an extremely rare disease in which people literally feel no pain. These people have a very tough life, and have to constantly manually inspect their bodies to make sure they don't have injuries they're not aware of (cuts, sprained ankles etc.), and are also essentially unable to participate in any kind of sports because of this.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#99

I dont think that this approach is a good idea at all. Our brains are complex entities, this treats it as a simple one. I think it will leave a hole in continuity and it may well be helpful, but residual awareness that something horrible has occurred will linger and it will be harder to resolve. I guess what I am trying to say is that the body remembers, even if we manage to pluck out one simple way the body goes abo…

I just want the option. I was a child. I never signed up in the business of dealing death and trauma unto others and myself. I would have loved to have had a doctor offer a hit of something to dull the imprinting of my worst day into my memories, emotions, and thought processes.

Am I supposed to live my life warning others about risks they don't care they are taking? I sometimes just want to be normal and forget what happened, and join the others in not thinking about people getting killed as part of my every day life.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#100
post #66

Earlier quoted context omitted.

That's a bit like asking "why is pain after an injury a 'disorder'"? Just like some people are left with persistent recurrent pain in an otherwise healthy and recovered limb (often known as rheumatism), some people are left with persistent recurrent stress after trauma - such as suddenly bursting out crying or cowering in fear after incidentally remembering trauma that happened 20 years ago while doing the dishes. Wh…

>That's a bit like asking "why is pain after an injury a 'disorder'"? It isn't. If anything that supports OPs point

I should have said (and I believe explained in the rest of the comment) that it's a bit like asking "why is pain after an injury a 'disorder'" of a person suffering from chronic pain. PTSD is a disorder beacause it is a chronic version of a completely normal accute reaction.
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