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Accelerated forgetting of a trauma event after a single dose of hydrocortisone

nature.com

81–90 of 112 posts

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#81
post #50

Earlier quoted context omitted.

PTSD is a disorder because people aren’t clearing or processing these things successfully and it becomes disruptive to their life. Sometimes it destroys their lives. If someone successfully processes the trauma in a way that isn’t disruptive, they by definition don’t have PTSD anymore. What you’re saying is a bit like saying someone who suffers from persistent, terrible constipation, to the point it causes them healt…

I don't really know if the poop analogy works here. If you were going to extend it here then this drug effectively makes you not feel like you have to poop - so instead it keeps the bile piling up in your intense for a few more days. Sure you prevent yourself from pooping but you do have to remove that eventually. Perhaps therapy is an intervention where they really can remove that waste from you with minimal invasiv…

If you’re looking for alternative analogies, feel free to use a colostomy one here if you want.

The point remains - saying ‘but can’t you just x’ when the problem is they can’t just x doesn’t really get you anywhere.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#82
post #66

Earlier quoted context omitted.

That's a bit like asking "why is pain after an injury a 'disorder'"? Just like some people are left with persistent recurrent pain in an otherwise healthy and recovered limb (often known as rheumatism), some people are left with persistent recurrent stress after trauma - such as suddenly bursting out crying or cowering in fear after incidentally remembering trauma that happened 20 years ago while doing the dishes. Wh…

>That's a bit like asking "why is pain after an injury a 'disorder'"? It isn't. If anything that supports OPs point

Disorder doesn't mean an unexpected outcome. It's a disruption in the norm for the system. The stable state for a human body is not constant pain.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#83

Combine with propranolol for maximum effect. A very overlooked drug that can be used in the treatment of many disorders related to anxiety, stress and fear. Without the risk of debiliating addiction benzos and benzolikes bring. https://pubmed.ncbi.nlm.nih.gov/14573324/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692719/

> propranolol [for] anxiety, stress and fear I recall reading that propranolol reduces the physical manifestations of anxiety, stress and fear, but you still feel it internally. For example, when used for stage fright, you won't fidget, stutter, blush, sweat, and have a racing heart beat, but you'll still feel the anxiety inside yourself.

Personal anecdote, i heard this as well, but after trying it, its very clear that it has positive results on my anxiety, not only physical (shaky hands...) but mental as well

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#84

I dont think that this approach is a good idea at all. Our brains are complex entities, this treats it as a simple one. I think it will leave a hole in continuity and it may well be helpful, but residual awareness that something horrible has occurred will linger and it will be harder to resolve. I guess what I am trying to say is that the body remembers, even if we manage to pluck out one simple way the body goes abo…

Is there anything to back up these ideas. Admittedly, I haven't read the article and am not familiar with the science. That said, these aren't things that can be figured out based on gut feeling or how something "seems". Your body doesn't remember anything, what are you talking about? There's no reason to think that it would be impossible to create a pill to mitigate some trauma. This seems like a dangerous obsession…

[deleted]

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#85

Why is stress after trauma a 'disorder'? And how is it a solution to drug people up, making them forget this?

A long time ago my wife shattered her wrist. In the ER, they explained that they needed to reset it so it could be put in a splint before surgery could be scheduled. They weren't going to use anesthetic. She would be conscious of the pain as they moved her wrist into position, but they'd give her something so she wouldn't remember the experience. 15+ years later she remembers telling them to go ahead and do it, then…

Interesting -- I recently had a similar experience (very bad wrist fracture), but they used a nerve block instead. I was conscious and it was painful, but not unbearably or traumatically so. I wonder why a nurse would choose one over the other.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#86

Earlier quoted context omitted.

Is there anything to back up these ideas. Admittedly, I haven't read the article and am not familiar with the science. That said, these aren't things that can be figured out based on gut feeling or how something "seems". Your body doesn't remember anything, what are you talking about? There's no reason to think that it would be impossible to create a pill to mitigate some trauma. This seems like a dangerous obsession…

Your body does remember things. See the book “The Body Keeps The Score”.

This is true, but only because the brain is a part of the body. The brain remembers things.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#87
post #86

Earlier quoted context omitted.

Your body does remember things. See the book “The Body Keeps The Score”.

This is true, but only because the brain is a part of the body. The brain remembers things.

That neglects all the other ecosystems in your body that lead you to behave the way you do.

Have you ever been hangry? How about the experience of chronic intestinal irritation worsening your depression? How do you feel in your head when you can’t stop your heart from racing after a stressful day of work? Those are all examples of the inverse.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#88

Earlier quoted context omitted.

I realize I am being downvoted so perhaps this is settled in literature. I know PTSD can be traumatic and takes different forms I suppose my confusion still comes from the fact that stopping intrusive thoughts is measured as good. But what if these intrusive facts are needed (just like therapy) to process things in the long run? I would understand if someone could ran a (very costly) experiment that said "Taking this…

Sure, these are all possibilities. With sufficiently able individuals who are sufficiently informed, we simply create the treatment and permit the individuals to select as required. For instance, the patient can choose to either suffer temporarily with the hope of the future positive outcome for the suffering or they can choose the immediate solution. If the patient is not sufficiently able to choose due to being men…

Removing a traumatic incident from your conscious memory doesn’t remove the trauma from you. The body keeps the score, and your brain is only a small part of the feedback loops that make you you.

Re: Accelerated forgetting of a trauma event after a single dose of hydrocortisone

#89
post #88

Earlier quoted context omitted.

Sure, these are all possibilities. With sufficiently able individuals who are sufficiently informed, we simply create the treatment and permit the individuals to select as required. For instance, the patient can choose to either suffer temporarily with the hope of the future positive outcome for the suffering or they can choose the immediate solution. If the patient is not sufficiently able to choose due to being men…

Removing a traumatic incident from your conscious memory doesn’t remove the trauma from you. The body keeps the score, and your brain is only a small part of the feedback loops that make you you.

I don't know man. I don't carry that much pain. My life is great and I can tell the tale without suffering the pain.
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