Earlier quoted context omitted.
>> The drug has been known for a long time but human trials always seems elusive Human trials of this will likely never happen. At least not publicly.
Why is that? Literally nobody will do the research in any country in the world because the Illuminati are everywhere?
Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
181–190 of 228 posts
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#182Earlier quoted context omitted.
[1] - "The figures are staggering: out of 35,000 children in care, more than 2,000 were physically or sexually abused by priests between 1936 and 1999" (Ireland alone) [2] - French Church abuse: 216,000 children were victims of clergy - inquiry 1. https://www.justiceinfo.net/en/45133-sexual-abuse-church-map... 2. https://www.bbc.com/news/world-europe-58801183
I saw no indication he was promoting the Church, rather than belief in G-d. (Not that it was a relevant reply anyway.)
https://knowyourmeme.com/memes/everyday-we-stray-further-fro...
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#183I'm a month into taking rapa and already I feel like it's having a noticeable effect. I'm curious what others on this threads dosage looks like. If you prefer to keep it private, you can email me directly (my email is on my profile). I'm currently taking 2mg once a week on my rest day; I started with 1mg and after 1 month added another MG. I'll continue each month until I reach 8MG once a week, which is the dosage th…
Finding a doctor who's up to "non-traditional" support can be a challenge, but you've inspired me to start that search.
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#184Earlier quoted context omitted.
Agree; it was very painful initially and not easy. But very simple conceptually!
I did caloric restriction for a year and eased into it gradually until I was eating two small meals a day. I had no ailments but weighed upward of 230 lbs, 104kg. In a year I went down to near zero body fat and weighed 150lbs/68kg. Unfortunately for my build and frame that made me look sickly so I started eating again and Ive settled around 165 and working to put on a little muscle. Overall I'd say I did this whole t…
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#185Earlier quoted context omitted.
What makes me scared about this is that it's immunosuppressive. The immune system is a very important part of the human body, and I worry that taking it could have terrible health impact after years of acting on your body lines of defense. What can you tell me about it?
Your concern is correct. Suppressing the immune system is a 2-edged sword - a little suppression in the right setting, is extremely beneficial, but go overboard and it is harmful. That's why in a perfect world, we would have large human trials with different dosages and iterate until we can get the maximum benefit and the least harm. The problem is, no one wants to do those trials because rapamycin is cheap and gener…
https://www.lifespan.io/campaigns/pearl-participatory-evalua...
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#186Earlier quoted context omitted.
Nicotinamide Mononucleotide, an unregulated supplement. Note also: > We found that, when data from all organisms studied were combined for each compound, aspirin resulted in the highest percent increase in average lifespan (52.01%), followed by minocycline (27.30%), N-acetyl cysteine (17.93%), nordihydroguaiaretic acid (17.65%) and rapamycin (15.66%), in average. [0] Though I'd consider whether flies and worms are go…
Is NMD related to NAD+?
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#187How does one find a doctor willing to prescribe these kinds of drugs for anti aging?
I'm not taking Rapamycin due to costs and immune system concerns, but when researching this niche (specifically, I'm interested in senolytics) I have found this forum with this list of doctors https://age-reversal.net/physician-directory/ Maybe it could help you.
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#188Earlier quoted context omitted.
Ages ago, I had a colleague who was deeply into hacking of his mTOR pathway. Among other things, this included a permanent calorie deficit and removal of all protein from his diet. I don't know if he's still alive. Maybe it was working a bit too well, I recall he looked like an extremely tall 13 year old with anorexia.
You can't synthesize some of the amino acids. I wouldn't think such a diet is survivable.
Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#189Re: Rapamycin, drug used in cancer therapy, emerges as powerful anti-aging remedy
#190Earlier quoted context omitted.
Besides satisfying their altruism they have nothing to gain and everything to lose if this miracle drug causes cancer in 5 years. I read up ok it. It can literally cause cancer.
Depending on where you are, everything can cause cancer. This website is known to the State of California to cause cancer.