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“No convincing evidence” that depression is caused by low serotonin levels
251–260 of 625 posts
Re: “No convincing evidence” that depression is caused by low serotonin levels
#252Like Vitamin D? Just take your pills and make us rich? If you don't get better is because you need more pills.
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Re: “No convincing evidence” that depression is caused by low serotonin levels
#253I thought it was widely accepted by now that the serotonin thesis was a bullshit story spread, among others, by Al Gore’s wife, maybe in good faith, maybe not. Edit: Tipper Gore; I did not remember her name (I’m not from the US). I read she was a big fan of the serotonin theory in a book (whose title I don’t remember at the moment).
Edit #2: The book is: Lost Connections: Uncovering the Real Causes of Depression, by Johann Hari
In chapter 2: The year after I swallowed my first antidepressant, Tipper Gore -- the wife of Vice President Al Gore -- explained to the newspaper USA Today why she had recently become depressed.
Just so that it's clear: I have nothing against Al Gore -- except that he lost the election.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#254When you look into the studies for antidepressants, the track record is abysmal. They’re not innocuous, trigger serious side effects, some are hard to quit, but more importantly they only make a difference in people with extremely severe depression. And doctors often downplay or don’t mention side effects honestly because they don’t want patients to not take them. The studies justifying antidepressants as effective t…
Any links to the Reddit threads if handy? I'm interested for personal issues and Reddit always comes much more useful than actual psychiatry in my case (not sarcasm, I frankly mean it).
I used “site:Reddit.com antidepressants” or with specific medicine names. Use ddg for that because the site: thing hasn’t worked on google in years and you’ll get poor results.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#255Earlier quoted context omitted.
You have the benefit of being casually disconnected from the topic and presenting yourself as intellectually curious. I have the experience of being alive because I was diagnosed and treated. Your curiosity about whether I get to live or die is up to you, but my place to speak to that isn’t up to you until I’m dead.
Quoted post unavailable.
What’s your point?
Re: “No convincing evidence” that depression is caused by low serotonin levels
#256SSRIs raise extra-synaptic serotonin levels within the first hour of taking them. However, their efficacy against depression takes weeks or even months to manifest. We've known this for decades, and as a result the "chemical imbalance" theory of depression hasn't been a real contender in depression research for a long, long time. The key thing to understand is that serotonin levels don't have to be low for SSRIs to i…
Funnily enough the one I used to take (Escitalopram) apparently has been found to begin permanently altering brain function after only a few hours of first ingestion. I was pretty happy with it. No pun intended
Also a happy customer of that one. It worked great for me even with a low dosage and didn’t otherwise negatively impact anything else.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#257When you look into the studies for antidepressants, the track record is abysmal. They’re not innocuous, trigger serious side effects, some are hard to quit, but more importantly they only make a difference in people with extremely severe depression. And doctors often downplay or don’t mention side effects honestly because they don’t want patients to not take them. The studies justifying antidepressants as effective t…
Yeah an unregulated and uncontrolled consumption of a poorly dosed hallucinogenic is totally better than a double-blind study of SSRI/SNRI. I swear, I do not reject the possibility that hallucinogenics can cure depression better than existing meds, but the almost religious enthusiasm for such a poorly studied chemical is deeply concerning. And yes, before you accuse me of being a pharma shill, I know that the lack of…
You do you of course.
You can grow your own mushrooms at home fairly easily and then you have more control over quality/contamination etc.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#258Earlier quoted context omitted.
> If people can be happy in concentration camps we can be happy in dead end office jobs. I don't think people in concentration camps are happy.
He's probably referring to the book Man's Search for Meaning. The book's conclusion is a bit controversial for this.
and Frankl, the writer, is rather controversial himself. Personally, I can't take what that guy writes seriously.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#259Earlier quoted context omitted.
You wish to vilify him. That's fine. It's extremely uncomfortable to find that this mathematician was right about something. I respect your feelings. But that doesn't alter the substance of his social critiques.
Sure it does. It's strange to argue that it wouldn't. Kaczynski is a madman, and perhaps the only person in the history of the United States whose quality of life was drastically improved by incarceration in a Supermax prison.
He lived out in the fresh air and sunlight.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#260SSRIs raise extra-synaptic serotonin levels within the first hour of taking them. However, their efficacy against depression takes weeks or even months to manifest. We've known this for decades, and as a result the "chemical imbalance" theory of depression hasn't been a real contender in depression research for a long, long time. The key thing to understand is that serotonin levels don't have to be low for SSRIs to i…
Sertraline suplementation wiped out depression almost completely from my system within two months. I had been depressed earlier for half a decade. Its been nearly 8 years since I took sertraline (stopped within 3 months) and I haven't had a depressive episode since.