Earlier quoted context omitted.
Just because you might have gotten a diagnosis that helped you doesn’t mean everyone has. I for one am actually interested if he can back up that claim. So when you as them to “Go on…”, please leave it at that. There’s no reason to be snarky.
doi:10.1001/jamanetworkopen.2021.5335 > Findings In this systematic scoping review of 334 published studies in children and adolescents, convincing evidence was found that ADHD is overdiagnosed in children and adolescents. For individuals with milder symptoms in particular, the harms associated with an ADHD diagnosis may often outweigh the benefits.
“No convincing evidence” that depression is caused by low serotonin levels
141–150 of 625 posts
Re: “No convincing evidence” that depression is caused by low serotonin levels
#142Earlier quoted context omitted.
I would recommend reading some history books before saying these are depressing circumstances.
Just because some people have suffered through worse doesn't mean that you can use that to invalidate someone else's suffering.
But when, for the vast majority of history, the population faced a much poorer, more monotonous, and less free existence than what the modern worker faces then you jolly well can.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#143What are the views on SSRIs prescribed for OCD and anxiety? The dosage for these conditions is much larger than for depression, often ten times or more.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#144Earlier quoted context omitted.
> The diagnosis and treatment of ADHD in adults but most especially in children is extremely suspect. Go on… (I’m adult diagnosed, for disclosure, but please do go on and tell me how suspect my diagnosis was, how I shouldn’t have been diagnosed as a child, how my medication is harmful. Go on and tell me about my life which you know better than I do.)
Just because you might have gotten a diagnosis that helped you doesn’t mean everyone has. I for one am actually interested if he can back up that claim. So when you as them to “Go on…”, please leave it at that. There’s no reason to be snarky.
You have the benefit of being casually disconnected from the topic and presenting yourself as intellectually curious. I have the experience of being alive because I was diagnosed and treated. Your curiosity about whether I get to live or die is up to you, but my place to speak to that isn’t up to you until I’m dead.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#145Re: “No convincing evidence” that depression is caused by low serotonin levels
#146Earlier quoted context omitted.
Don't take it personal. Both things can be true, you can have adhd and adhd can be overdiagnosed, doesn't mean that none of those diagnostics are valid. I'm sure you must be tired of people telling you about how overdiagnosed adhd is, I'm sorry about that, but don't take it personal, it's just a person on the internet.
> Don't take it personal Oh I take it personally. I’m alive today because I sought diagnosis and treatment. I very nearly wasn’t alive from the consequences of being undiagnosed and untreated. I very probably would be dead today if I had taken this “just person on the internet” more seriously than I already had. I’m more than tired of people offering their ignorant opinions about stuff they don’t understand.
On the other hand, the state threw a ADD diagnosis on me because I was bored in school, pumped me full of a methamphetamine analog and put me into classes with profoundly disabled people ruining my social life from a early age. I'd stare at the wall in my bedroom for hours due to the drugs, eventually my parents stopped giving them to me when I was at home, but that lead my dad to try them, and eventually get addicted to meth proper himself.
I dropped out at 15 and taught myself computer science, so it was all provably horseshit but it sure made my life harder as a child.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#147Earlier quoted context omitted.
> The diagnosis and treatment of ADHD in adults but most especially in children is extremely suspect. Go on… (I’m adult diagnosed, for disclosure, but please do go on and tell me how suspect my diagnosis was, how I shouldn’t have been diagnosed as a child, how my medication is harmful. Go on and tell me about my life which you know better than I do.)
e: [deleted]
What’s your point?
Re: “No convincing evidence” that depression is caused by low serotonin levels
#148I'm going to go out on a limb and guess the prominence of depression is largely caused by a broken interface with the world at large. The traps created by modern society wherein you struggle for other people's benefit are better designed than ever before. What our social machine procedurally treats as progress is advances in subjugation. Depression may often be an artifact of "efficiency" with respect to extracting v…
You're right: you've gone way out on a limb.
Re: “No convincing evidence” that depression is caused by low serotonin levels
#149SSRIs raise extra-synaptic serotonin levels within the first hour of taking them. However, their efficacy against depression takes weeks or even months to manifest. We've known this for decades, and as a result the "chemical imbalance" theory of depression hasn't been a real contender in depression research for a long, long time. The key thing to understand is that serotonin levels don't have to be low for SSRIs to i…
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Re: “No convincing evidence” that depression is caused by low serotonin levels
#150Earlier quoted context omitted.
I think OP is just saying that 'ADHD' is not that valid of a diagnosis, in terms of any kind of underlying 'pathology'. The fact that many people appear to benefit from the use of 'medication' (i.e. amphetamines and derivatives, from Adderall to Desoxyn(methamphetamine) to Ritalin), is mostly unrelated to any 'diagnosis'. Personally I think all drugs should be legal and people should be able to take whatever they thi…
You got it. The shakiness of this entire thing also shows in how the medication for ADHD is chosen: by trial and error. For real.
Ignoring the fact that basically all drug development outside of the computational stuff is large amounts of trial and error, there is ample evidence that ADHD results from dysfunction of specific neural pathways, and stimulant medication benefits ADHD individuals (more than just "speed helps everyone focus").
> This literature is increasingly contributing to the notion that the pathophysiology of ADHD reflects abnormal interplay among large-scale brain circuits. Moreover, recent studies have begun to illuminate the mechanisms of action of pharmacological treatments.