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Governor Newsom announces California will make its own insulin

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Re: Governor Newsom announces California will make its own insulin

#31

Post by raldi »

gandalfgeek wrote: post #28
enahs-sf wrote: post #18

Sometimes I feel like this is the endgame where the US overall kind of declines but California starts managing itself better and operates almost like an independent country. Probably wishful thinking but would be great.

I can’t relate at all to that sentiment. California has got to be one of the most bloated and wasteful state governments in the entire US. High taxes and nothing to show for it. The entrenched far left seems bent on destroying the middle class, driving out business, regulating everything to death and displacing merit as a selection factor. Whatever glory Cali has— tech, entertainment, farming, weather, natural beauty…

High taxes on newcomers. Nearly nonexistent taxes on dynastic families.

Re: Governor Newsom announces California will make its own insulin

#32

Post by taeric »

gandalfgeek wrote: post #28
enahs-sf wrote: post #18

Sometimes I feel like this is the endgame where the US overall kind of declines but California starts managing itself better and operates almost like an independent country. Probably wishful thinking but would be great.

I can’t relate at all to that sentiment. California has got to be one of the most bloated and wasteful state governments in the entire US. High taxes and nothing to show for it. The entrenched far left seems bent on destroying the middle class, driving out business, regulating everything to death and displacing merit as a selection factor. Whatever glory Cali has— tech, entertainment, farming, weather, natural beauty…

I can't claim you are wrong. But I do question when the evidence is so murky. A lot of what folks think they want in efficient systems are systems that would fail because of how efficient they were run.

That is, what evidence do you have that the success is in spite of government? Is there a comparable government or system that is doing better? Why? Or why not?

Re: Governor Newsom announces California will make its own insulin

#33

Post by refurb »

Spooky23 wrote: post #21
refurb wrote: post #3

Doesn’t make a lot of sense. Generic insulin’s are already being made. Why not just buy those?

Because pharmaceutical research is hitting a wall in many areas, and companies are “catching and killing” generic manufacturers specifically to extract more revenue from long invented products. Government should absolutely play in this space. Hell, one of the primary anti-fungal creams (NYStatin) was developed by a female researcher and state employee in the 1960s.

But it’s not a new insulin, it’s just some manufacturer. Plenty of generic insulin’s exist already. Why build a new plant just to make something that’s already sold?

Re: Governor Newsom announces California will make its own insulin

#34

Post by refurb »

witheld wrote: post #4
refurb wrote: post #3

Doesn’t make a lot of sense. Generic insulin’s are already being made. Why not just buy those?

Presumably they're going to make good insulin people can actually use, rather than pig insulin that practically doesn't work.

No they aren’t. They’re making a generic of an existing insulin. The same stuff other companies make.

Re: Governor Newsom announces California will make its own insulin

#35

Post by adolph »

This is a pretty interesting public-private partnership proposal that Newsom seems to have been working on for a while.

Budget Request Summary

HCAI requests one-time $100 million General Fund, available until 2025-26, for the CalRx Biosimilar Insulin initiative. Through a contract partnership, the State would invest $50 million towards the development of low-cost biosimilar insulin products, an additional $50 million towards a California-based insulin manufacturing facility. HCAI also requests $2.8 million General Fund, over four years, for state operations to fulfill requirements of the partnership, including monitoring, oversight, and legal compliance. The insulin products are expected to be widely available to Californians, through a variety of outlets.

https://esd.dof.ca.gov/Documents/bcp/2223/FY2223_ORG4140_BCP...

Re: Governor Newsom announces California will make its own insulin

#36

Post by hnburnsy »

av3csr wrote: post #6

This site seems to be provide a through price analysis of insulin nowadays https://www.goodrx.com/healthcare-access/research/how-much-d...

Thanks, that is a great analysis, especially the details on modern insulin.

What would be even better to know is what people are paying. It is well known that the AWP or average retail price in this case is not close to average price paid.

Re: Governor Newsom announces California will make its own insulin

#37

Post by usrn »

ipnon wrote: post #24

How hard would it be to found an insulin startup? This seems like the kind of problem designed to be intractable, the "busy work" of bureaucratic private health care systems.

It sounds to me like the modern process is just working up GMO yeast matabolites. I feel like the main issue is probably going to be patents and not something technical.

Re: Governor Newsom announces California will make its own insulin

#38

Post by clarkmoody »

650REDHAIR wrote: post #22
magila wrote: post #16

Earlier quoted context omitted.

Healthcare is the most heavily regulated industry in the US. Many of those regulations were written specifically to minimize or eliminate the influence of market forces. You can't reasonably say the market has failed when it has been so tightly constrained by regulation.

Regulation that was lobbied into reality by… who?

Cronyism is the opposite of a free market.

Re: Governor Newsom announces California will make its own insulin

#39

Post by hnburnsy »

Here are the budget details on this...

https://esd.dof.ca.gov/Documents/bcp/2223/FY2223_ORG4140_BCP...

"This proposal will use $50 million in funding to enter into a partnership with a contract manufacturer to develop and bring to market interchangeable biosimilar insulin products in both vial and pen form."

"This proposal also includes an additional $50 million for the construction of an insulin manufacturing facility based in California. CalHHS will partner with the Governor’s Office of Business and Economic Development (GO-Biz), leveraging its expertise in business investment services such as site review, permit assistance, and other related activities. CalHHS will lean on GO-Biz’s expertise to mitigate risk and properly execute the proposed manufacturing facility, if CalRx proceeds with this component of the project."

Re: Governor Newsom announces California will make its own insulin

#40

Post by colinmhayes »

magila wrote: post #16
hourago wrote: post #2

it's obvious that many medical supplies have an inelastic demand so are easily manipulated. When the market fails governments need to step in.

Healthcare is the most heavily regulated industry in the US. Many of those regulations were written specifically to minimize or eliminate the influence of market forces. You can't reasonably say the market has failed when it has been so tightly constrained by regulation.

Of course you can. Regulation is one of the most common market failures.
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