Was just in Mexico and took them 3-4 days in a row (0.5mg - 2mg) to sleep after drinking or the next morning. Slept amazing those few nights. Felt terrible 2 days after the last one, and even now close to a week later I don’t even feel that good. Pretty sure they are terrible for you.
Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
181–190 of 400 posts
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#182Earlier quoted context omitted.
Propranolol is very commonly prescribed for anxiety in the UK. I take it as needed and it works wonders, but it does make me a bit lethargic. It doesn't completely eliminate the low level anxiety but it stops it ending up in a viscous panic cycle.
Widely used for anxiety in my country as well but not an optimal choice due to the cardiovascular effects. As you noted, it can cause fatigue.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#183I was prescribed benzos because of sleeping issues, but I was also taking phenibut at the same time. After about 3 weeks of using large doses of the benzos every night, I stopped taking them, but a year later I still feel pangs of withdrawal sometimes when I get stressed. It took me another 4 months to get off the phenibut and a month or so after that before my sleep returned to normal. There were months where I mayb…
But I think they're a valid last-resort treatment for panic attacks if we're talking less then twice a month-ish range. Reason being is that they will reliably work every time, and for many people including myself just knowing we have it can prevent panic attacks. But you still need to be treating your anxiety with therapy and/or other medications (but especially therapy) - its only a last resort.
And I mean using it very sparingly, I only take it once every few months, and only the lowest dose (klonopin @0.5mg max) to take the edge off so I can work through it, not enough to remove all the anxiety.
EDIT: Oh and anyone with addiction issues should stay away from these. They work _every time_ which is so tempting to use for just mild anxiety and my understanding is higher doses then what I take are euphoric so stay clear.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#184Benzos are pretty terrible drugs in general. The physical addiction potential and withdrawal people are going through are enough to dissuade me from touching them. For folks dealing with anxiety, I recommend trying propranolol. It is not as powerful, but sometimes it is enough to achieve the desired effect and the side effects are way less severe.
Just a warning to anyone who has asthma, propranolol is a older beta blocker from the 1960s and has made asthma worse in various trials. My doctor and psychiatrist recommended I use other classes of medications.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#185Earlier quoted context omitted.
I have friend who was at nursing school, and she'd get them prescribed for the few occasions where she had to do a presentation, as she would get extremely nervous. She never took them after. Maybe she could've addressed the issue differently, but it worked for her, and she never got hooked. But milage varies, and so on. She also told me that at the hospital, benzos are readily available and they kinda hand then out…
I’ve reacted differently to different benzos. One did nothing. Another triggered one hell of a mood swing (I’m bipolar). Finally settled on Klonopin, which has a long half-life. It seems to be less.. harsh? Psychoactive medications are fun…
Now that I think of it, a benzo actually did help me once, when I got my wisdom teeth removed. Made me a bit more calm about it. But it was fairly tolerable overall anyways.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#186Earlier quoted context omitted.
picamilon is banned? That's dumb, soon they will ban l-theanine and taurine? I really don't think you can get addicted to picamillon like phen or benz
Some supplements are basically unregulated medications. I found out the hard way that L-Theanine does not mix well with bipolar disorder. I suspect it inactivated the mood stabilizer I was on.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#187Earlier quoted context omitted.
Just a warning to anyone who has asthma, propranolol is a older beta blocker from the 1960s and has made asthma worse in various trials. My doctor and psychiatrist recommended I use other classes of medications.
Yes. Asthma is treated with beta agonists. Beta blockers will block the effect of the asthma medication.
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#188I took 1 benzodiazepine bill once about 15 years ago and I still remember the effect--instant total relaxation. I remember thinking that it felt too good and that it's something I shouldn't let myself have again. Hearing about its long term effects, I feel somewhat lucky.
The first time I took Xanax I cleaned my kitchen and it went from mildly embarrassing to quite presentable in an hour or two. I could actually execute the things I wanted to do without fighting though ridiculous feelings. I am treated like an addict or ridiculous when I tell doctors I'd rather not "try SSRIs" or a series of strange sedating substances because they're all so afraid of prescribing something with addict…
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#189I was prescribed benzos because of sleeping issues, but I was also taking phenibut at the same time. After about 3 weeks of using large doses of the benzos every night, I stopped taking them, but a year later I still feel pangs of withdrawal sometimes when I get stressed. It took me another 4 months to get off the phenibut and a month or so after that before my sleep returned to normal. There were months where I mayb…
> I tell everyone to never take benzos for any reasons You can't generalise your experience. Everybody is different and that's the doctor's job to assess whether the benefits outweigh the cost, considering the patient and their problems. Personally, I've been taking benzos very occasionally for 20 years (never more than a few days at a time) and they helped me overcome difficult times. Never had the slightest addicti…
Re: Long-term benzodiazepine use causes synapse loss and cognitive deficits in mice
#190Earlier quoted context omitted.
Doctors prescribe benzos for sleep issues and tell you they are safe? Do you live in the US?
is that a question? Benzos are not safe despite what many doctor believe. I'm in EU.
I had a friend who wanted to stop smoking cannabis and got alprazolam prescribed for that by his doctor (it was in EU). In my opinion it would be better to stick to cannabis than switch to Xanax.
I myself tried talking with my family doctor about my benzo addiction. I was addicted to etizolam, a RC benzo popular at the time. He seemed not to believe me that it was possible to get benzos without a prescription, and told me that I was wrong and couldn't have a benzo addiction.