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Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

universityofcalifornia.edu

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Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#401

Post by silisili »

JohnJamesRambo wrote: post #133

I used to eat sardines every day trying to get the health benefits of fatty fish. They were packed in soybean oil. I drank the oil too. With time I began to have bizarre mental issues that I finally tracked down to the sardines. Sardines packed in olive oil don’t cause this issue. That’s my anecdata to share.

Interesting, thanks for sharing, I always avoided the oil ones on taste/principle. As a fan of canned fishes, have you tried sardines in tomato sauces, or herring in dill or mustard sauce? Fantastic, but a little harder to find.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#402

Post by thadk »

loudtieblahblah wrote: post #259
stjohnswarts wrote: post #102

Earlier quoted context omitted.

So does this mean they should have similar effects on the body or that they are different enough to be essentially just two different fats that are significantly different enough not to draw conclusions that ALA causes the same (potential) effects as LA as brought forth in the article?

They're both polyunsaturated fats. While an over-simplification Omega3s (which ALA is) tend to be anti-inflammatory and have tons of positive effects of cardiovascular health (up to a point - more on this later) while Omega6s, which are necessary for our survival, do tend to have an inflammatory effect. The goal is to be high-ish in Omega3s without getting mercury poisoning and low in Omega6s. The modern diet - so if…

Thanks for these, really enjoying your posts here to complement the things I've figured out.

You might also enjoy the brief remarks from this old OpenVisConf USDA parallel coordinates data visualization+video of animals aggregating the things we feed them.

I find it sort of underscores your point of linoleic acid in egg likely not being stable over history, if you feed a chicken differently, even though USDA treats food as if they are, in data: https://twitter.com/thadk/status/1352034735548194817?s=20

Point on eggs: https://news.ycombinator.com/item?id=30459016

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#403

Post by thaumasiotes »

unfocussed_mike wrote: post #377
thaumasiotes wrote: post #367

Earlier quoted context omitted.

Speaking as an American... I was aware that "broiling" was a cooking method, but I have no concept of what it involves. After checking a dictionary, I still don't -- wikipedia redirects "broiling" to "grilling", and Merriam-Webster defines "broil" as "to cook by direct exposure to radiant heat: grill", with an example given of "broil the steak in the oven". I would be more likely to use "bake" for heating something i…

Grilling is _under_ a hot surface. Like broiling. But when you broil you use a different pan. Or something. Now if you want a really weird distinction: baking and roasting. Same appliance, much more similar temperatures than you might think, often only subtly different prep. You might think, no, you "bake" things that rise or are transformed by the process, like dough. But you might also "bake" potatoes and fish. Or…

> Grilling is _under_ a hot surface.

Absolutely not. Grilling is on top of a hot surface, often underneath the open atmosphere. The sky is not a hot surface.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#404

Post by weq »

JohnJamesRambo wrote: post #133

I used to eat sardines every day trying to get the health benefits of fatty fish. They were packed in soybean oil. I drank the oil too. With time I began to have bizarre mental issues that I finally tracked down to the sardines. Sardines packed in olive oil don’t cause this issue. That’s my anecdata to share.

Overconsumption of canned food can have this effect of poisioning the consumer. No matter what its cooked in.

If you eat alot of tuna/canned stuff, and u have weird health problems. Try removing it from your diet.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#405

Post by heavyset_go »

JohnJamesRambo wrote: post #133

I used to eat sardines every day trying to get the health benefits of fatty fish. They were packed in soybean oil. I drank the oil too. With time I began to have bizarre mental issues that I finally tracked down to the sardines. Sardines packed in olive oil don’t cause this issue. That’s my anecdata to share.

If you eat out, soybean oil is used a lot for cooking and it's also included in some blended oils that restaurants use.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#406

Post by antattack »

davidparks21 wrote: post #378
robwwilliams wrote: post #256

Do not take this work seriously unless you are a male inbred mouse of the C57BL/6N persuasion. This is a classic N=1 study of one sex and one genome of mouse. As such this work is of almost no know relevance to other strains of mice, let alone to humanity. If you want an example of how mice dietary studies should be done then look to the National Institute on Aging and its Interventions Testing Program. They use both…

I think this is a fair point. I see other comments pointing out the value in this as exploratory research. There's some middle ground here though. I think studies like would serve the lay reader and non-scientific community by including a disclaimer sentence in the abstract about not extrapolating conclusions from this. Their opening sentence does the opposite, "Soybean oil consumption has increased greatly in the pa…

The article also states: "A caveat for readers concerned about their most recent meal is that this study was conducted on mice, and mouse studies do not always translate to the same results in humans."

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#407

Post by heavyset_go »

sinyug wrote: post #39
simonsarris wrote: post #4

> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance. > “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and…

> Soybean oil I saw this video about seed oils a few months back.[1] Some of the information there tracked stuff I have been reading for a while. Decided to switch over completely to coconut oil and ghee (clarified butter). A comment on the video that matches my view on the subject: > If you want to be healthy just do the exact opposite of everything we were told about nutrition by mainstream experts for decades [1]…

Coconut oils are high in lauric and palmitic acids, both of which have tomes of evidence pointing to them causing and exacerbating cardiovascular disease. The MCTs in coconut oil might have some positive health effects alone, but research on the consumption of coconut oil itself suggest that it increases risks of CVD.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#408

Post by depressedpanda »

loudtieblahblah wrote: post #271
Pxtl wrote: post #137

Earlier quoted context omitted.

Fixating on lineolic acid is kind of hard when basically all high-heat vegetable oils contain a lot of it. If lineolic acid is the problem then basically every unsaturated cooking oil other than olive oil is now unusable. Maybe canola, depending on how much lineolic acid is safe.

canola is probably the best out of the bunch but it's still too high in omega6s. PUFAs - as cooking oils - should be totally and utterly avoided. People should be using butter, ghee, beef tallow, coconut oil, avocado oil (which is a little higher in omega6s that i'd like but it's mostly a monosaturated fat), duck fat, emu oil. Macademia nut oil is higher in monosaturated fats than olive oil and has a higher smoke poi…

As I understand it, canola is the same as rapeseed oil, or is a refined version of it. For what I think are obvious reasons, I stay away from refined oils.

However, where I live I can get locally produced cold pressed "extra virgin" rapeseed oil. How would you say that compares to canola oil regarding how healthy (or trashy) it is?

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#409

Post by ghastmaster »

JohnJamesRambo wrote: post #156
hashimotonomora wrote: post #136

Earlier quoted context omitted.

Care explaining what bizarre mental issues?

I guess it would best be described as enhancement of repetitive, obsessive thoughts and just in general not feeling good and even angry for the rest of the day after eating them. It was a really weird time.

Get your gallbladder checked. Oil causes the gallbladder to squeeze bile. If you have instruction (stones/polyp), the obstruction causes inflammation.

That inflammation (chole ystitis) can cause a plethora of health issues.

Some oils trigger more output of bile than others. Do not consider all fat sources equal when it comes to bile production from the gallbladder.

I had gallbladder issues for many years, before classic signs appeared. I had cognitive decline, general discomfort, fatigue, rapid heart rate, secondary infections, and other non typical indicators that in retrospect were due to my gallbladder. Typical symptoms appeared very close to when I was able to identify the source. Unfortunately, if left untreated, it can rupture and kill a person, albeit rarely.

Either way, I wish you the best.

PS: In the USA you can get an ultrsound for $140. False positives and negatives do occur. Some people have no noticable pathologies, yet removal of the gallbladder alleviates gastro intestinal symptoms.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#410

Post by ghastmaster »

digitalsushi wrote: post #224
JohnJamesRambo wrote: post #156

Earlier quoted context omitted.

I guess it would best be described as enhancement of repetitive, obsessive thoughts and just in general not feeling good and even angry for the rest of the day after eating them. It was a really weird time.

I have the same thing. It took me ten years to rule things out. Plain as day, if I have soy oil, I will go a little wayward emotionally, mentally, and if I have enough, also noticeable skin issues - canker sores, flaking skin, scalp pimples, and random itchy patches I'll scratch to bleeding. Oh, and if I have enough, in a short amount of time, I can easily trigger a migraine. Sushi with soy oil, mayonnaise (soybean o…

See my comment about the gallbladder please.
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