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Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

universityofcalifornia.edu

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Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#81

Post by mrfusion »

09bjb wrote: post #62
atlantas wrote: post #25

My understanding is that most of the oils we use are unhealthy. They are highly processed and inflammatory. The good oils are avocado oil, extra virgin olive oil and coconut oil. Is this correct?

It's more nuanced than that but you could do a lot worse than that list. Fat profile matters, and smoke point matters, e.g. olive oil is great but if you're frying stuff with it you're turning a lot of it toxic; avocado oil is better for high heat.

So olive oil would be bad to use in the air fryer?

Also what’s the best substitute for vegetable oil for baking?

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#82

Post by slothtrop »

kansface wrote: post #67
09bjb wrote: post #62

Earlier quoted context omitted.

It's more nuanced than that but you could do a lot worse than that list. Fat profile matters, and smoke point matters, e.g. olive oil is great but if you're frying stuff with it you're turning a lot of it toxic; avocado oil is better for high heat.

Any word on peanut oil?

same pitfalls as most vegetable oils, and high in omega 6, which can throw off your omega3:6 ratio if you consume lots, which increases risk of obesity among other things.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#83

Post by hungryforcodes »

criddell wrote: post #26
globalise83 wrote: post #11

Seems from the article that soybean oil contributes to making people obese and unhappy.

Maybe. The study only looked at mice though.

And mice happiness might be hard to evaluate.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#84

Post by Bedon292 »

I should not be surprised that soybean oil is the most widely consumed oil, but I had not actually realized it. I had to look it up; It is in margarine, mayonnaise, and most vegetable oils. And I just had not payed that close of attention.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#85

Post by simonsarris »

zhte415 wrote: post #47
simonsarris wrote: post #4

> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance. > “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and…

The article specifically mentions, following that cited part, on Linoleic acid: > the research team has not yet isolated which chemicals in the oil are responsible for the changes they found in the hypothalamus. But they have ruled out two candidates. It is not linoleic acid, since the modified oil also produced genetic disruptions; nor is it stigmasterol, a cholesterol-like chemical found naturally in soybean oil.

But the team DID note that "the SO + CO diet caused more weight gain over the 16-week study than the other HFD" (As opposed to the modified soybean diet). This is a quote from the paper, not the article.

According to the paper the Linoleic acid composition of the oils in question are:

    soybean:     %52.90
    modified SO:  %7.42  (aka plenish)
    coconut:      %0.06
So while some of the genetic expressions may exist in both, both have LA, and the higher LA = higher obesity according to the paper authors (they did not give a graphic for the obesity differences, unfortunately)

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#86

Post by JPKab »

This stuff should be banned outright.

Fatty liver is a big deal. Insulin resistance is as well. Both lead to high blood pressure, heart disease, and Type II diabetes.

The impacts on our health care system from these conditions dwarf anything else. It should be noted that these conditions, along with obesity dramatically increased the death/hospitalization rate for COVID.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#87

Post by ______-_-______ »

baby-yoda wrote: post #59
atlantas wrote: post #25

My understanding is that most of the oils we use are unhealthy. They are highly processed and inflammatory. The good oils are avocado oil, extra virgin olive oil and coconut oil. Is this correct?

avocado might not be so trustworthy, see: https://news.ycombinator.com/item?id=30105062 ghee is a great alternative IMO.

Has anyone done the research to find a reputable olive oil brand?

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#88

Post by pigeonhole123 »

crowbahr wrote: post #69
simonsarris wrote: post #4

> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance. > “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and…

From the study: > One additional note on this study — the research team has not yet isolated which chemicals in the oil are responsible for the changes they found in the hypothalamus. But they have ruled out two candidates. It is not linoleic acid, since the modified oil also produced genetic disruptions; nor is it stigmasterol, a cholesterol-like chemical found naturally in soybean oil. 1. We're not mammals that exp…

1. We have common genes going back to mammals who did experience torpor. 2. A study doesn't "own" their data and have exclusive right to interpret this data 3. Someone selling something that they think is beneficial to their customer, does not mean it is not beneficial. I would say most people who sell things honestly think their customers will benefit from their product.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#90

Post by iratewizard »

softwarebeware wrote: post #29
simonsarris wrote: post #4

> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance. > “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and…

It's interesting to try and square the multiple conflicting findings about the effect of the modern diet on the brain and other observed phenomena such as The Flynn Effect ( https://ourworldindata.org/intelligence ) that mean IQ is increasing over time.

There was a good article I read years ago (and can't find again with how useless Google has become) which talked about IQs rising but people getting dumber. The main theory it had was adapting to the tests and teaching skills that help answer questions on IQ tests.
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