It's worth pointing out that the "genetic changes" in question are changes in gene expression .
Thank you. I have never heard a biologist refer to a change in gene expression as a genetic change. The latter usually refers to a mutation.
Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
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Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#72Taking account that this is unproven in humans -- it's enough for me to avoid soybean oil, as cooking oil choice is not very important for my palate. That said, which oils would you use for frying and baking? Most high smoke point oils are, like soybean, polyunsaturated, so I'd guess that they could have some of the same (proposed) negative effects. Bonus points if the alternative is widely available (I see potential…
Humanity has been using Olive Oil for at least 1000 years. So that seems pretty safe to me.
Humanity has also been drinking alcohol for thousands more, doesn't mean it's safe.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#73> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance. > “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and…
> Linoleic acid is what induces torpor
Is this the same as ALA in flax-seed oil that is supposedly good for us?
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#74Earlier quoted context omitted.
>ghee Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations: https://pubmed.ncbi.nlm.nih.gov/2887943/ "Substantial amounts of cholesterol oxides were found in ghee (12.3% of sterols), but not in fresh butter"
> Indian ghee We have been using ghee in India for thousands of years. If immigrant Indians are having problems, they should look into what changed in their diet and lifestyle after they immigrated.
> We have been using ghee in India for thousands of years
That in of itself is not a particularly good argument. What has been the life expectancy for those thousands of years?
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#75It's worth pointing out that the "genetic changes" in question are changes in gene expression .
Could you elaborate on that? It doesn't surprise we that "genetic changes" is used sensationally, just would like to know what is actually happening and whether it's uncommon or something pretty normal?
Your DNA is the "cookbook", of what your body can make.
Gene expression is what your body happens to be making (and how much) from the cookbook - and's entirely normal.
I'd have reserved "Genetic changes" for alterations to the cookbook.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#76I went all carnivore 15 months ago, and a side effect of that is the removal of all seed oils from the diet. The results include complete remission of my diabetes and associated fatigue and brain fog, the loss of more than 60 excess pounds, greater joy of life and emotional stability, and a new, regular desire to exercise and move my body. I don't know how much of that is about cutting out seed oils. I am getting lar…
>I went all carnivore 15 months ago, and a side effect of that is the removal of all seed oils from the diet. The results include complete remission of my diabetes
[...]
It's equally plausible that all the effects stemmed from removing carbs.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#77> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance. > “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and…
It's interesting to try and square the multiple conflicting findings about the effect of the modern diet on the brain and other observed phenomena such as The Flynn Effect ( https://ourworldindata.org/intelligence ) that mean IQ is increasing over time.
Maybe 'IQ', a somewhat suspect measure, isn't very useful.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#78Earlier quoted context omitted.
>ghee Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations: https://pubmed.ncbi.nlm.nih.gov/2887943/ "Substantial amounts of cholesterol oxides were found in ghee (12.3% of sterols), but not in fresh butter"
> Indian ghee We have been using ghee in India for thousands of years. If immigrant Indians are having problems, they should look into what changed in their diet and lifestyle after they immigrated.
> We have been using ghee in India for thousands of years.
Doing something unhealthy for “thousands of years” does not make it healthy.
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#79> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance. > “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and…
It's interesting to try and square the multiple conflicting findings about the effect of the modern diet on the brain and other observed phenomena such as The Flynn Effect ( https://ourworldindata.org/intelligence ) that mean IQ is increasing over time.
Especially interesting to put all of that in the context of recent reports of plateaus and reversals in the Flynn Effect, at least in certain European countries: (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042097/), contrasted with wider meta-analyses that still show an increase, although less than previously thought, and dependent on age group and country development status. (https://www.sciencedirect.com/science/article/abs/pii/S01602...)
Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)
#80> The same UC Riverside research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance. > “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and…
> Linoleic acid is what induces torpor Is this the same as ALA in flax-seed oil that is supposedly good for us?
ALA is alpha-linolenic acid (the essential omega-3 fatty acid). LA is linoleic acid (the essential omega-6 fatty acid). They are the "raw materials" of the Arachidonic Acid Cascade.