Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

An Experience with Modafinil

erowid.org

Post reply on HN
Print view View original

171–180 of 363 posts

Re: An Experience with Modafinil

#171

Post by tomcam »

cjohnson318 wrote: post #97
inter_netuser wrote: post #59

Earlier quoted context omitted.

Caffeine would be illegal to possess, if it were invented yesterday. 80% of people couldn't distinguish I.V. cocaine from I.V. caffeine in some study I am unable to locate at the moment, which I think involved Nora Volkow from NIH, either as PI or collaborator.

Shooting in the dark here, but I imagine dose size is an important variable in a study like this. At 500mg, I'm pretty sure a member of the LDS* could tell the difference between coffee and cocaine. [*] I'm only calling out the LDS community here because they don't consume coffee, or cocaine, generally speaking.

No post body was provided.

Re: An Experience with Modafinil

#172

Post by netizen-936824 »

inter_netuser wrote: post #59
ipnon wrote: post #49

What's remarkable to me is that modafinil is less toxic than caffeine[0], and possibly even less addictive[1], but we all know which is illegal for recreational use and which is coffee. Regulations are sticky. The FDA follows the precautionary principle. Political game theory incentivizes restricting what the electorate can do rather than giving them more freedoms, and being blamed for whatever harm may fall upon the…

Caffeine would be illegal to possess, if it were invented yesterday. 80% of people couldn't distinguish I.V. cocaine from I.V. caffeine in some study I am unable to locate at the moment, which I think involved Nora Volkow from NIH, either as PI or collaborator.

I wasn't able to find a specific research study yet but here's this

>Intravenous caffeine also resembles cocaine, she points out.

https://archive.fo/bLX94

Re: An Experience with Modafinil

#173

Post by inter_netuser »

bb88 wrote: post #145
darawk wrote: post #141

Earlier quoted context omitted.

As someone who has consumed both IV cocaine and IV caffeine, this is ridiculous. They are very, very distinguishable.

Or you're in that 20% that can. He still has an out.

https://pubmed.ncbi.nlm.nih.gov/7714788/ >“The mood effects but not the physiological effects of intravenous caffeine were similar to those previously observed with cocaine in studies using similar methods and subjects.”

https://archive.fo/bLX94 >This is obviously worrying. “Cocaine is one of the most addictive substances of abuse,” says Volkow. “Ritalin we give to children.” She stresses, however, that taking a stimulant orally is very different to injecting or snorting it. Intravenous caffeine also resembles cocaine, she points out.

h/t to those with better google-fu than mine. all from this thread.

fwiw, caffeine is also the most common adulterant in cocaine, so chances are your iv cocaine also had a good amount of caffeine and lidocaine in it.

....but why would you even try pure i.v. caffeine though? cocaine i can understand, but caffeine?

Re: An Experience with Modafinil

#174

Post by thesaintlives »

inter_netuser wrote: post #59
ipnon wrote: post #49

What's remarkable to me is that modafinil is less toxic than caffeine[0], and possibly even less addictive[1], but we all know which is illegal for recreational use and which is coffee. Regulations are sticky. The FDA follows the precautionary principle. Political game theory incentivizes restricting what the electorate can do rather than giving them more freedoms, and being blamed for whatever harm may fall upon the…

Caffeine would be illegal to possess, if it were invented yesterday. 80% of people couldn't distinguish I.V. cocaine from I.V. caffeine in some study I am unable to locate at the moment, which I think involved Nora Volkow from NIH, either as PI or collaborator.

No post body was provided.

Re: An Experience with Modafinil

#175

Post by Dma54rhs »

bloqs wrote: post #142
ipnon wrote: post #49

What's remarkable to me is that modafinil is less toxic than caffeine[0], and possibly even less addictive[1], but we all know which is illegal for recreational use and which is coffee. Regulations are sticky. The FDA follows the precautionary principle. Political game theory incentivizes restricting what the electorate can do rather than giving them more freedoms, and being blamed for whatever harm may fall upon the…

Be extremely careful with it. A friend of mine developed some horrifying skin issues after relatively light use.

Can you share a bit more information?

Re: An Experience with Modafinil

#176

Post by inter_netuser »

rflrob wrote: post #154
inter_netuser wrote: post #59

Earlier quoted context omitted.

Caffeine would be illegal to possess, if it were invented yesterday. 80% of people couldn't distinguish I.V. cocaine from I.V. caffeine in some study I am unable to locate at the moment, which I think involved Nora Volkow from NIH, either as PI or collaborator.

Is this the study? “The mood effects but not the physiological effects of intravenous caffeine were similar to those previously observed with cocaine in studies using similar methods and subjects.” https://pubmed.ncbi.nlm.nih.gov/7714788/

Thanks. It could be, does look familiar, but I cannot get access to the full text for some reason.

Re: An Experience with Modafinil

#177

Post by netizen-936824 »

refurb wrote: post #151
inter_netuser wrote: post #59

Earlier quoted context omitted.

Caffeine would be illegal to possess, if it were invented yesterday. 80% of people couldn't distinguish I.V. cocaine from I.V. caffeine in some study I am unable to locate at the moment, which I think involved Nora Volkow from NIH, either as PI or collaborator.

Cocaine was isolated long before current drug laws, so I'm not sure I buy the argument "if it were invented today". Cocaine wasn't invented today and was banned.

It was banned because people associated it with "scary black people"

Re: An Experience with Modafinil

#178

Post by netizen-936824 »

r_hoods_ghost wrote: post #128
oceanghost wrote: post #93

Earlier quoted context omitted.

You know not of what you speak.

~15 years of taking Adrafinil and then Modifinil on prescription and "recreationally" says otherwise. The actual effect of a drug and then the psychosomatic effect of those who expect it to have a certain effect are two very different things.

Also, not everyone is the same neurologically. People seem to write off this difference as moot. It's not

Re: An Experience with Modafinil

#179

Post by thesaintlives »

Mostly all true. I have taken modafinil quite a bit. You can buy it in India from a chemist for next to nothing. If you take it every day for a couple of weeks in small amounts the efficacy does get less. If you increase the dose you don't get more returns. Used sparingly for study or concentrating it is nice. It is also good if you are tired and have to do some long task that requires little but constant attention - driving or flying for example. Take as much as you need, do your job then sleep, all good. Piracetam is also to be recommended. Again don't do it all the time and be sensible. Smart drugs work but getting something for nothing is always tricky...

Re: An Experience with Modafinil

#180

Post by inter_netuser »

refurb wrote: post #151
inter_netuser wrote: post #59

Earlier quoted context omitted.

Caffeine would be illegal to possess, if it were invented yesterday. 80% of people couldn't distinguish I.V. cocaine from I.V. caffeine in some study I am unable to locate at the moment, which I think involved Nora Volkow from NIH, either as PI or collaborator.

Cocaine was isolated long before current drug laws, so I'm not sure I buy the argument "if it were invented today". Cocaine wasn't invented today and was banned.

modafinil was invented today and is scheduled, aka illegal to possess without prescription.

however, modafinil it's actually cleaner and even safer than caffeine. That's the point. a less toxic, safer drug is illegal to possess (w/o rx).

How would you justify making a much more toxic drug completely unrestricted, what would be your argument? We'd just have cops showing confiscated bags of big bad evil drug caffeine to kids in DARE classes.

Post reply on HN