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Covid-19 breakthrough data

coronavirus.health.ny.gov

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Re: Covid-19 breakthrough data

#31

Post by awb »

Scene_Cast2 wrote: post #16

One thing to note is that the effectiveness metric also includes the behavioral and populational differences. I'd personally really like to know what the metric would be if (hypothetically, just for analysis) the vaccine was a placebo. For example, if the people who get the vaccine are generally more able to work from home, then the metric would still be significantly above zero. Just for clarity, I believe that the…

We’ll have to think of a different methodology because it’s not ethical to issue placebo vaccines during a pandemic.

Re: Covid-19 breakthrough data

#32

Post by zach_miller »

encryptluks2 wrote: post #14
mhh__ wrote: post #10

Earlier quoted context omitted.

Which studies?

https://www.ons.gov.uk/news/statementsandletters/coronavirus... "those who have received three doses of a vaccine and test positive for COVID-19 are more likely to be infected with infections compatible with the Omicron variant compared with those who are unvaccinated"

Feels like that’s more a statement about the efficacy of the vaccine against Delta vs Omicron. “…and test positive for COVID-19…” already narrows the groups down to only the positive cases, it’s not a statement about those groups’ relative sizes.

Re: Covid-19 breakthrough data

#33

Post by awb »

throwawaybutno wrote: post #27
awb wrote: post #5

Interesting that while the odds of the vaccine protecting against infection are near all-time lows (mid 70s), vaccine protection against hospitalization is near all-time highs (mid-90s). Also interesting that this data treats 14-days+ after last shot as fully vaccinated, so presumably two-shot and three-shot people are both treated as “fully vaccinated”. > Fully-vaccinated people may have received additional or boost…

Published effectiveness against Omicron infection is under 10%. This data is simply wrong.

Source?

Re: Covid-19 breakthrough data

#34

Post by wand3r »

encryptluks2 wrote: post #20
wand3r wrote: post #11

Earlier quoted context omitted.

Can you post one of these articles? What is the contention, people who are vaccinated are more likely to get omicron?

Here is the Pfizer-CEO board member approved truth ministry version: https://www.reuters.com/article/factcheck-omicronvariant-bre... Basically, statistics only matter when it shows what they want you to see, but when it says that triple vaxxed are 8% more likely to get Omicron than unvaxxed then you are drawing conclusions.

I dont really appreciate the conspiratorial or political framing, but I will contend that these results seem to support your claim.

Re: Covid-19 breakthrough data

#35

Post by rubyfan »

encryptluks2 wrote: post #20
wand3r wrote: post #11

Earlier quoted context omitted.

Can you post one of these articles? What is the contention, people who are vaccinated are more likely to get omicron?

Here is the Pfizer-CEO board member approved truth ministry version: https://www.reuters.com/article/factcheck-omicronvariant-bre... Basically, statistics only matter when it shows what they want you to see, but when it says that triple vaxxed are 8% more likely to get Omicron than unvaxxed then you are drawing conclusions.

It’s ironic that the article is about people using the study to spread misinformation about the results of the study.

Social media users are misrepresenting these findings (on Omicron’s apparent ability to breakthrough vaccine protection) by saying those vaccinated are more susceptible to infection overall.

Re: Covid-19 breakthrough data

#36

Post by taeric »

encryptluks2 wrote: post #14
mhh__ wrote: post #10

Earlier quoted context omitted.

Which studies?

https://www.ons.gov.uk/news/statementsandletters/coronavirus... "those who have received three doses of a vaccine and test positive for COVID-19 are more likely to be infected with infections compatible with the Omicron variant compared with those who are unvaccinated"

That... Is a different statement. It says that they are more likely to have a specific variant, given that they got infected. It did not say they are more likely to get infected. Right?

Re: Covid-19 breakthrough data

#37

Post by Mystlix »

awb wrote: post #5

Interesting that while the odds of the vaccine protecting against infection are near all-time lows (mid 70s), vaccine protection against hospitalization is near all-time highs (mid-90s). Also interesting that this data treats 14-days+ after last shot as fully vaccinated, so presumably two-shot and three-shot people are both treated as “fully vaccinated”. > Fully-vaccinated people may have received additional or boost…

you are protected from infection only if you have a huge number of antibodies since they can immediately overpower the virus when it gets in. when the antibodies are few and the virus comes in you have to wait for the trained t-cells to produce enough of them to again overpower the virus, so you get sick for a short time and then get better. of course the quality of a vaccine determines how quickly and effectively the dormant t-cells are able to produce antibodies, so a very very very good vaccine can even protect from infection years after inoculation, and that's why the CDC has recently asked for more research in order to produce these kind of vaccines for the long term

Re: Covid-19 breakthrough data

#38

Post by FabHK »

Scene_Cast2 wrote: post #16

One thing to note is that the effectiveness metric also includes the behavioral and populational differences. I'd personally really like to know what the metric would be if (hypothetically, just for analysis) the vaccine was a placebo. For example, if the people who get the vaccine are generally more able to work from home, then the metric would still be significantly above zero. Just for clarity, I believe that the…

Well, one important confounder is age (older people tend to be more vaccinated), but they control for that.

Many other confounders cannot easily be controlled for, but is there any reason to assume that they're correlated with the outcome? It could be that vaccinated people are more careful in terms of meeting other people.

At any rate, we had big RCTs at the beginning that demonstrated efficacy against the then prevailing variant (alpha, I assume).

It'll be tricky to repeat an RCT at this stage.

Re: Covid-19 breakthrough data

#39

Post by twofornone »

pstoll wrote: post #25
roamerz wrote: post #17

Earlier quoted context omitted.

Probably a statistic that they don’t want have in their possession anyhow.

He didn’t go the hospital. That doesn’t change the overwhelmingly positive benefits of “hospitalization rates”.

The vast majority of cases don't end up in the hospital, vaccinated or otherwise. People seem to forget this fact.

Re: Covid-19 breakthrough data

#40

Post by manfredzab »

encryptluks2 wrote: post #14
mhh__ wrote: post #10

Earlier quoted context omitted.

Which studies?

https://www.ons.gov.uk/news/statementsandletters/coronavirus... "those who have received three doses of a vaccine and test positive for COVID-19 are more likely to be infected with infections compatible with the Omicron variant compared with those who are unvaccinated"

You’re misinterpreting (unintentionally or otherwise) this statement.

All this is saying is that P(Omicron variant | positive test AND 3x vaccine) > P(Omicron variant | positive test AND no vaccine).

In no way this is implying P(Getting Omicron | 3x vaccine) > P(Getting Omicron | no vaccine).

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