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Serotonin selectively influences moral judgment and behavior

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Re: Serotonin selectively influences moral judgment and behavior

#181

Post by loves_mangoes »

andrei_says_ wrote: post #180
Jerrrry wrote: post #176

Earlier quoted context omitted.

If I get my mail today, I will let you know.

I hope it helps you - but are there any studies on how it works and why? What’s the mechanism of “disassociation” resulting in “getting better”?

The honest answer is that we don't know.

Experimentally, it works. There are theories (google will give you a couple vaguely plausible mechanisms), but it's too early to say. And it's likely that the antidepressive effect of ketamine has nothing to do with its NMDA antagonism, given that other NMDA receptor antagonists do not work as antidepressives.

Neuroscience theory lags far behind applied psychiatry, so all know is people whose depression resists normal treatment now have another very promising option, with a very different mechanism from normal antidepression treatment.

Re: Serotonin selectively influences moral judgment and behavior

#182

Post by astrange »

ipaddr wrote: post #156
astrange wrote: post #153

Earlier quoted context omitted.

He was a hypnotherapist and in the FBI at the same time? I didn't think they allowed moonlighting. You certainly can get memories back this way; the problem is that they'll be fabricated, especially from childhood. I agree both these kinds of therapy are effective though.

Forensic Hypnosis is a career path. FBI still works with hypnotherapists.

Much of forensic science is fake, so that doesn't show much. They still do polygraphs too.

Re: Serotonin selectively influences moral judgment and behavior

#183

Post by n8cpdx »

azth wrote: post #161
n8cpdx wrote: post #134

Earlier quoted context omitted.

Uncomfortable questions indeed. It is honestly hard to comprehend how people believe in it at all. I understand that people do, but it’s mystifying, like a belief in god or even Santa Claus. Regardless, justice systems (incentives and accountability) and incarceration (incentives, and ideally rehabilitation) have nothing to do with free will. Any connection between free will (presence or absence) and the justice syst…

It's actually hard and absurd not to believe in a Creator.

Who is the Creator’s creator? If you can accept that the Creator came into being and created the universe, you can skip a step and just say the universe came into being.

Re: Serotonin selectively influences moral judgment and behavior

#184

Post by skissane »

sneak wrote: post #174
skissane wrote: post #141

Earlier quoted context omitted.

Morals are (at least in part) based on generalising instinct. Most people would be instinctively repelled and outraged if they saw an adult torturing a child – morality is not that instinctive feeling itself, but when we reflect upon that feeling intellectually, especially when in doing so we universalise it, moving from "I am repelled and outraged by this, so I won't do it and do I what I can to stop others from doi…

> Most people would be instinctively repelled and outraged if they saw an adult torturing a child This, regardless of how you feel about the subject matter, is a factually false statement. That's not how instincts work, or what they are. Additionally, even without that error, the statement holds false.

> This, regardless of how you feel about the subject matter, is a factually false statement. That's not how instincts work, or what they are.

How do they work? What are they then?

> Additionally, even without that error, the statement holds false.

How? Why?

Re: Serotonin selectively influences moral judgment and behavior

#185

Post by Jerrrry »

andrei_says_ wrote: post #180
Jerrrry wrote: post #176

Earlier quoted context omitted.

If I get my mail today, I will let you know.

I hope it helps you - but are there any studies on how it works and why? What’s the mechanism of “disassociation” resulting in “getting better”?

Dissociatives are the most under-appreciated class of drugs.

Mechanisms of action are difficult to be objective about. It is a lot more complicated than dopamine and serotonin regulation and uptake, receptors and antagonists.

Today was pleasant, despite every reason not to be. It's like the "hope" qualia.

Re: Serotonin selectively influences moral judgment and behavior

#186

Post by plutonorm »

mxmilkiib wrote: post #177
plutonorm wrote: post #17

Earlier quoted context omitted.

Not available in the UK because reasons.

Not available directly from a GP, but if one gets referred to a clinical psychiatrist they can permit a prescription.

True. But it won't be easy. You will mostly likely be put on combination therapies first. Then onto combo SSRIs and Antipsychotics, then maybe you might get something that ups dopamine, maybe. If you look a bit bipolar though you'd likely go onto a mood stabiliser (i.e. calm the f down you over-active neurons, have some more gabba/ block those calcium channels etc). and personally that's what worked best for me, over active mind induced perpetual exhaustion -> anhedonia from the stress of a mind that never stops.

Re: Serotonin selectively influences moral judgment and behavior

#187

Post by andrei_says_ »

Jerrrry wrote: post #185
andrei_says_ wrote: post #180

Earlier quoted context omitted.

I hope it helps you - but are there any studies on how it works and why? What’s the mechanism of “disassociation” resulting in “getting better”?

Dissociatives are the most under-appreciated class of drugs. Mechanisms of action are difficult to be objective about. It is a lot more complicated than dopamine and serotonin regulation and uptake, receptors and antagonists. Today was pleasant, despite every reason not to be. It's like the "hope" qualia.

Thank you, this is what I was looking for. So - on biochemistry level we don’t know why it works. But somehow, controlled temporary disassociation seems to… interrupt negative ideation?

Also TIL “qualia” - what a wonderful word.

Re: Serotonin selectively influences moral judgment and behavior

#188

Post by andrei_says_ »

loves_mangoes wrote: post #181
andrei_says_ wrote: post #180

Earlier quoted context omitted.

I hope it helps you - but are there any studies on how it works and why? What’s the mechanism of “disassociation” resulting in “getting better”?

The honest answer is that we don't know. Experimentally, it works. There are theories (google will give you a couple vaguely plausible mechanisms), but it's too early to say. And it's likely that the antidepressive effect of ketamine has nothing to do with its NMDA antagonism, given that other NMDA receptor antagonists do not work as antidepressives. Neuroscience theory lags far behind applied psychiatry, so all know…

Thank you, this is what I was looking for.

Re: Serotonin selectively influences moral judgment and behavior

#189

Post by pregseahorses »

petesergeant wrote: post #147
tsol wrote: post #95

Earlier quoted context omitted.

My experience was the opposite. In fact, after taking medication to fix it I later stopped because of this naturalistic fallacy. I knew it was bunting some of my emotions and I figured whatever the drugs are doing I can do with lifestyle changes. 10 years later, a daily habit of exercise and cold showers, a variety of daily natural supplements like turmeric and magnesium, and a career later.. I was no different. I'd…

Exactly the same experience, including the quitting and restarting. My only regret about the meds is waiting so long to start

Exactly my experience. I can't forget the intensity of the shock when I realized that people around me do not 'normally' dread the day. I am still excited about my hobbies and family, but do not find myself going into fight-or-flight mode for perceived fears. An added bonus that enhances my quality of life: I do not get my weekly migraines while I'm on the pill - they do return to normal as soon as I stop.

Re: Serotonin selectively influences moral judgment and behavior

#190

Post by [deleted] »

tablespoon wrote: post #42
aantix wrote: post #40

Earlier quoted context omitted.

Have you tried any supplements? SSRIs aren’t the only promising solution.

> Have you tried any supplements? > SSRIs aren’t the only promising solution. I don't think it's very helpful to vaguely bring up "supplements" like that. There are so many , and they range from being harmful, to being placebos, to being actually helpful. Plus there's a huge amount of utter quackery around them. Do you have any specific "promising" ones in mind?

[deleted]
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