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U.S. surgeons transplant pig heart into human patient

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Re: U.S. surgeons transplant pig heart into human patient

#271
post #26

You might be asking, why a pig? I don't know, but forever ago I wrote software for a cardiovascular imaging lab and pigs were their primary test subjects. I was like, "why pigs?" and the PI was like, "Imaging-wise, pig hearts aren't too different from humans. Plus, we can give them a heart attack in the scanner and not go to jail. Some labs use dogs. I just can't do that."

Humans are pig ape hybrids.

Re: U.S. surgeons transplant pig heart into human patient

#272
post #61

Earlier quoted context omitted.

Pigs are really common in biomedical testing. They are physically a similar size and weight to humans. They also reach maturity in about 6 months. Much cheaper to raise than primates, and more likely to get approval for testing. My friends in biomed grad school named one of theirs cyber pig because it has about 30 different experiments ran on it before it was killed, and afterwards it was portioned out for further te…

What is it about primates that make them expensive?

Primates typically need to be raised in very large colonies to be healthy, and to be able to take from the colony without damaging it, there need to be many many primates (some colonies are in the hundreds).

The Rhesus monkey is a popular one for biomedical testing for a variety of reasons.

Re: U.S. surgeons transplant pig heart into human patient

#273

Earlier quoted context omitted.

On the axiom that betraying such faith leads to æternal damnation in the afterlife, it seems a strategic choice to me. It would perhaps only be strange that a man might hold such an axion, not that he acts in accordance with it.

Few (if any) Jews believe in eternal damnation. Generally speaking, Judaism places very little emphasis on the afterlife, and there's no widely-held doctrine about it. To the extent there's a shared belief at all, it's that everybody goes to a place called Sheol, without differentiation by merit.

That's so strange that Christianity and Judaism can have such divergent views on the afterlife. I guess it never occurred to me (as a former Christian) that Christian views on the afterlife are totally derived from the new testament.

Re: U.S. surgeons transplant pig heart into human patient

#274
post #267

Earlier quoted context omitted.

I'd want to question why I'm doing it. For example do I have kids I need to stick around to support? Or am I just going to be discharged to mostly play video games, alone? Because I don't see a need to extend that life. Then I'd want to think about what it symbolizes. Is it really so irrational to just let my body die when my God-given guts fail instead of depending on the hands of man to possibly convert my body int…

Conversely, there's this well-worn pseudo-parable: A fellow was stuck on his rooftop in a flood. He was praying to God for help. Soon a man in a rowboat came by and the fellow shouted to the man on the roof, “Jump in, I can save you.” The stranded fellow shouted back, “No, it’s OK, I’m praying to God and he is going to save me.” So the rowboat went on. Then a motorboat came by. “The fellow in the motorboat shouted, “…

I've heard this one, yes. From my experience of learning about the God that I pray to, I highly doubt He's sending me commenters asking me one liners about seat belts and dialysis to convince me that the monk I admire was wrong, and that I should change my mindset to become more like the atheists I'm surrounded by.

Rowboats, helicopters etc. in a flood, prima facia, seem to be more in character as a deliverance from a natural disaster. My interpretation of that parable is that this man has a vainglorious hope to be saved via an undeniable miracle of mystical, luminous teleportation so he can point to it and go "Look, see! I was right all along".

Re: U.S. surgeons transplant pig heart into human patient

#275
post #124

Earlier quoted context omitted.

I think the nervous system is really the only part that I'd have ethical concerns about. If they can grow a pig with a 99% human heart, I don't see why that should be more ethically concerning that harvesting a 100% pig heart.

The concern, I think, that it's obviously unethical to grow a 100% human child and then harvest its heart, right? You're talking about a living, feeling, thinking person! Causing them to suffer or to die is morally wrong, conversely, their life and their right to life have precious, incalculable, sacred value. The thought of harvesting, murdering a human being for one of their organs is repulsive, harvesting them for…

This is an ethical concern which is so completely removed from reality that it borders on satire. This is why no one takes bioethicists seriously anymore.

Re: U.S. surgeons transplant pig heart into human patient

#276

Earlier quoted context omitted.

Weird how this is said without a shred of sympathy or concern for an intelligent, helpless creature. Weirder how it can be said without a sympathetic or concerned response. I hope we can someday move beyond seeing animals as a mere resource.

I think for things like this, being dispassionate is a coping mechanism. If you engage the sympathy part of your brain, you won’t be able to do it. If you don’t do it, then humans die instead.

John Wycliffe (1340 AD): "How should God approve that you rob Peter and give this robbery to Paul in the name of Christ?"

https://en.wikipedia.org/wiki/To_rob_Peter_to_pay_Paul

Re: U.S. surgeons transplant pig heart into human patient

#277

Earlier quoted context omitted.

Weird how this is said without a shred of sympathy or concern for an intelligent, helpless creature. Weirder how it can be said without a sympathetic or concerned response. I hope we can someday move beyond seeing animals as a mere resource.

I know someone who worked with mice but switched fields, he explained he could no longer do it because even though they are heavily inbred for research, each one had a different personality when in his hands and killing all of them took too much of a mental toll after years of work.

Reminds me of this:

https://www.atlasobscura.com/places/monument-to-the-laborato...

Re: U.S. surgeons transplant pig heart into human patient

#278
post #26

You might be asking, why a pig? I don't know, but forever ago I wrote software for a cardiovascular imaging lab and pigs were their primary test subjects. I was like, "why pigs?" and the PI was like, "Imaging-wise, pig hearts aren't too different from humans. Plus, we can give them a heart attack in the scanner and not go to jail. Some labs use dogs. I just can't do that."

I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals. - Winston S. Churchill

Re: U.S. surgeons transplant pig heart into human patient

#279
post #123
post #100

Earlier quoted context omitted.

An organic heart can self-repair itself, unlike the mechanical one. It's also "proven" to potentially last 100 years with no maintenance required.

A mechanical heart could in theory be more reliable and less susceptible to issues of biology.

Biological tissue is several orders of magnitude superior to mechanical organs.

Re: U.S. surgeons transplant pig heart into human patient

#280
post #61

Earlier quoted context omitted.

Pigs are really common in biomedical testing. They are physically a similar size and weight to humans. They also reach maturity in about 6 months. Much cheaper to raise than primates, and more likely to get approval for testing. My friends in biomed grad school named one of theirs cyber pig because it has about 30 different experiments ran on it before it was killed, and afterwards it was portioned out for further te…

What is it about primates that make them expensive?

Supply? Pigs are both abundant and easily found in the United States. There aren't primate breeding lots. You need to go into a jungle to find them.
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