Dr. Katelyn Jetelina, MPH PhD, has a nice substack from perspective of an epidemiologist. Two notable recent Omicron posts on that substack: The potentially scary aspects: https://yourlocalepidemiologist.substack.com/p/state-of-affa... The potentially good news: https://yourlocalepidemiologist.substack.com/p/there-is-good... Obviously it is still early, but imo those 2 posts give a decent lay of the land.
" We can easily see that in many graphs, but my favorite is below from New York City, showing a clear distinction in hospitalizations among vaccinated compared to unvaccinated people " I don't see this as much here in Ontario. Among the vaccinated as of today there is a 10.10/100k hospitalization status vs 16/100k for the unvaccinated (and 11.9 for one-dose). The hospitalization rate among the vaccinated is climbing…
This still shows a greater than 10x difference in outcomes. Additionally, the "unvacccinated" population includes people naturally vaccinated by virtue of having a previous case.
It could very well evolve into a form that is mild enough and different enough from the vaccine spike that brings the unvaccinated and vaccinated hospitalization rates to convergence. Respiratory illnesses in general harm the elderly and immunocompromised disproportionately. But if that becomes the end game where COVID is still circulating, vaccines are no longer as effective at preventing serious illness, because the general severity has gone down, that is also a good outcome as it is what we have always lived with.
Colds and flus have always killed 10s of thousands a year. COVID killed many more because it was particularly severe. Just as the flu of 1918 is still with us today in a less harmful form (H1N1) This virus has a global reservoir and will never run its course entirely before mutating again most likely. Just like colds and flus before it.