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Experimental depression treatment is nearly 80% effective in controlled study

med.stanford.edu

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Re: Experimental depression treatment is nearly 80% effective in controlled study

#131
post #125

Earlier quoted context omitted.

It took me a while to realize that most people don't consider suicide as one of a few strategies to deal with everyday problems. Thought process: I don't want to do my homework. I could (A) get up and do it, or (B) kill myself. Happily, I've learned to dissociate myself from the part of my consciousness that thinks that way.

Quoted post unavailable.

Or, you could try to be nicer when somebody makes themselves vulnerable to you.

Re: Experimental depression treatment is nearly 80% effective in controlled study

#132
post #125

Earlier quoted context omitted.

I've had depression for 20+ years and the best way I would describe it is like this: Think of that little "kick" you get when you think of something you want to do. Maybe you like eating ice cream, maybe you like playing tennis, whatever it is... that feeling, that subconscious little mental boost that gets you up off your ass, and moving... is completely absent in the depressed mind. That spark that initiates and su…

It took me a while to realize that most people don't consider suicide as one of a few strategies to deal with everyday problems. Thought process: I don't want to do my homework. I could (A) get up and do it, or (B) kill myself. Happily, I've learned to dissociate myself from the part of my consciousness that thinks that way.

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Re: Experimental depression treatment is nearly 80% effective in controlled study

#133
post #125

Earlier quoted context omitted.

It took me a while to realize that most people don't consider suicide as one of a few strategies to deal with everyday problems. Thought process: I don't want to do my homework. I could (A) get up and do it, or (B) kill myself. Happily, I've learned to dissociate myself from the part of my consciousness that thinks that way.

Quoted post unavailable.

So indelicately put.. Comes across (to my Euro mind) as an order doubled with an insult.

Re: Experimental depression treatment is nearly 80% effective in controlled study

#134

Hey! I didn't under go SAINT TMS specifically, but I have undergone TMS therapy. Reading this article I'm not sure how different what I received actually is compared to SAINT, but TMS absolutely changed my life. I was referred to TMS after a rash of different medications and years of talk therapy fell short on relieving the worst of my symptoms. Many of the benefits the patients in this article discuss are ones I rec…

Looks like it is just more tailored to your particular brain neurocircuitry and give more pulses but instead of in 1 session over ten small sessions in a day. Sounds like it only makes sense that this works even better!

Re: Experimental depression treatment is nearly 80% effective in controlled study

#135
post #125

Earlier quoted context omitted.

It took me a while to realize that most people don't consider suicide as one of a few strategies to deal with everyday problems. Thought process: I don't want to do my homework. I could (A) get up and do it, or (B) kill myself. Happily, I've learned to dissociate myself from the part of my consciousness that thinks that way.

Quoted post unavailable.

When the target of your objectively reasonable directive is self-admittedly of the mindset "I could (A) get up and do it, or (B) kill myself", you may want to reconsider the wording.

Re: Experimental depression treatment is nearly 80% effective in controlled study

#136
post #123

Cost (and availability/wait time for nations with public healthcare) are a concern. I know several people who received conventional TMS for 30 minutes a day for six weeks. That cost them, with insurance, about $1500. It was effective for an average of six months. This treatment is an order of magnitude more time spent in the machine, even if over a shorter period. What will it cost? Will it be accessible to those who…

Depression has an enormous economic impact. Fatigue and pain (depression related symptoms) are some of the most common reasons people can't work in the wealthier part of the world. If the treatment costs $4000 dollars yearly and makes the difference between debilitating depression and functioning taxpayer that is self financing for the public healthcare.

Not to mention the personal suffering.

Re: Experimental depression treatment is nearly 80% effective in controlled study

#137

> “The treatment, known as Stanford accelerated intelligent neuromodulation therapy (SAINT) or simply Stanford neuromodulation therapy, is an intensive, individualized form of transcranial magnetic stimulation. In the study, remission typically occurred within days and lasted months. The only side effects were temporary fatigue and headaches.” > “Twenty-nine people with treatment-resistant depression participated in…

> Makes me wonder what percentage of the placebo group improved? For future reference, assuming this is a clinical trial, data from clinical trials is available online. This is the kind of statistic that you'd be able to find.

But it must be difficult to do so, or you would have done a lmgtfy link or comment like "Just search the study title and look at table 12."

Re: Experimental depression treatment is nearly 80% effective in controlled study

#139
post #63

"Soma", ladies & gentlemen

Searched comments for this. Found at bottom, battered and faded, but yes, that is exactly what it would be, I agree. However, I also accepted that being glib about it and calling it soma ignores what it's like to live with clinical, total physiological depression and that this is real hope.

I'm not scolding either, I literally laughed at this myself and came here to say something along those lines, but giving a generous sop to some people I fundamentally disagree with - it was a laugh that signalled an opportunity to empathize with the subject of it. Feels gross even saying that, and I believe the soma thing is a legit question, but even at the risk of arming enemies, it's worth elevating the commentary a bit because of what is on the other side of it. We don't make b-movie zombie references whenever there is a new chemo treatment with promise against cancer, and if someone depressed said to me, "hey thanks and f-you for making my need for the first viable treatment just as stigmatized as the disease," I would have earned the criticism honestly.

I also realize this is what only a truly master soma propagandist would say as part of a campaign for the coming change, but my realization was sincere, and anyway, there's also no way they're this good.

Re: Experimental depression treatment is nearly 80% effective in controlled study

#140

Earlier quoted context omitted.

I have some questions if you don't mind: Was it expensive? Are there any downsides? Do you think TMS is, like psychedelic therapy, potentially useful for people without depression (i.e. the "betterment of well people")?

https://www.youtube.com/watch?v=5BKSWnuF3pA

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