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Children develop robust and sustained cross-reactive immunity after Covid

nature.com

151–160 of 285 posts

Re: Children develop robust and sustained cross-reactive immunity after Covid

#151
post #23
post #12

Earlier quoted context omitted.

>What a stroke of luck that we are here vs a more infectious strain of Delta or some other nightmare that would keep this rolling. How do we know we won't end up with that? Omicron evolved from Beta, which had pretty well disappeared when Omicron sprung up.

The better omicron is at spreading the more people it will confer natural / hybrid immunity to, reducing the dangers of a future variant.

Do you have sources for that? Because isn’t that exactly what has not happened with all the existing variants?

Re: Children develop robust and sustained cross-reactive immunity after Covid

#152

Finally some glimmers of hope in moving past Covid.. if Omicron continues on its current track of highly infectious but less serious —- and infection confers reactive immunity to a variety of strains, we could be closer to the endemic but manageable end game. Good vaccines + mild severity illness are basically the best case. What a stroke of luck that we are here vs a more infectious strain of Delta or some other nig…

> Good vaccines + mild severity illness are basically the best case.

If it was a common cold or a flu ? Maybe.

> “Although COVID-19 has been described as a respiratory syndrome, evidence supports the involvement of multiple organ systems, with fibrosis, and inflammation in the lung, heart, kidneys, central nervous system (CNS), liver, adrenal glands, bone marrow, lymph nodes, and gastrointestinal tract. SARS-CoV-2 infection has also been associated with serious thrombotic complications, including strokes, pulmonary embolism, and cardiac injury.”

https://www.wsws.org/en/articles/2021/11/10/leon-n10.htm

Endemic we want ? Then we want yearly (or 6months it seems) vaccines. And masks. And ventilation.

Reinfections will get more severe with age once vaccine or infection elicited sera wanes.

> What a stroke of luck that we are here vs a more infectious strain of Delta or some other nightmare that would keep this rolling.

Omicron being the new kid on the block doesn't mean another more dangerous variant isn't building itself up in a body somewhere.

Maybe two years into the pandemic is not enough to let the reality sink in that we will never come back to before. Maybe we need ten years but by then we'll all be used to the new normal anyway. “Learn to live with the virus”, they said. Indeed.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#153

Earlier quoted context omitted.

Yes. We should do that. We won't. Pro: everyone is fine, the hospitals aren't overwhelmed, the anti-vaxxers will be fine along with everyone else. Con: can't speak with disgust and disdain anymore to those who disagree with your medical opinions, or have concerns with how quickly you're forcing your experimental medications on the entire planet. Not going to happen. I've already seen the usual suspects talking about…

> everyone is fine Except the people who aren't. > the hospitals aren't overwhelmed Except the ones that are. > forcing your experimental medications on the entire planet No more experimental than any other vaccine; due to how quickly COVID spread, we were able to do the same level of testing on the vaccine as for any other medication. It's as safe as anything else you take.

vaccine trials usually last 2 years alone from a quick glance

Re: Children develop robust and sustained cross-reactive immunity after Covid

#155
post #142
post #90

Earlier quoted context omitted.

Another coronavirus probably caused a worldwide pandemic starting in 1889. It killed a lot of people, but the survivors gained natural immunity which gave them significant protection against symptomatic reinfections. The same virus HCoV-OC43 is still endemic today. This seems relevant to the current pandemic. https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/175... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC…

'The evidence 1889-1890 outbreak was caused by a coronavirus has been referred to as "weak" and "conjectural" in an analysis of the literature' Seems this theory has only gained traction in the last 2 years. Looking into it further, case fatality rate of during the 1889-90 outbreak seemed to be 0.1-0.28, much lower than Covid-19 has been.

Our data on the 1889-90 pandemic is pretty thin. We don't have any reliable records on deaths in poorer countries so the error bars are quite wide.

A lower infection fatality rate in that previous pandemic is not at all surprising. Back in 1889 elderly people made up a much lower fraction of the population. And there was a lower rate of co-morbid conditions such as obesity, diabetes, and hypertension.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#156

Earlier quoted context omitted.

Recently released (days ago) US census data disagrees. Only New York had higher outmigration in absolute numbers than California.

California would be expected to have the largest outmigration given that it has the largest population.

"Better than New York" is damning with faint praise.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#157
post #130

Earlier quoted context omitted.

From examining Swedish death spike data, you can see that viruses like COVID occur about once a decade, the last being Swine Flu in 2009: https://swprs.org/wp-content/uploads/2020/10/sweden-monthly-... Its just that, using Swedish data again, Western societies are significantly more aged: eg. there 120,000 80-84 year old men (prime COVID death territory) in 2020, vs only 101,000 in 2009. Its similar in many other Wes…

I think taking a shot every six month is totally worth it if that will let your grandma live two years longer.

IMO casual masking (stores, airplanes, etc) and a shot every 6 months isn't the annoying part about covid, it's the economic damage of lockdowns, school closures, social gatherings missed, extreme isolation of the vulnerable, travel not happening and the supply chain logjams it has been creating everywhere as a result. You can't go to an office consistently and have face to face lunches coworkers with as a result.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#158

Earlier quoted context omitted.

> Does anyone truly think its acceptable to let people die in ambulances outside of hospitals because a highly contagious disease filled all the hospital beds and medical staff is too fatigued to work? Maybe people with a political axe to grind pretend to think that. Given widespread availability of vaccines, I think it is acceptable to turn away any non vaccinated people without medical exemptions to preserve hospit…

Will it be you turning these people away? Always puzzles me to see people suggesting all these “just let them die” silver bullet algorithms.

It wouldn't be explicit turning away, but if your in a triage situation, most doctors and medical systems will focus on the most time serious and the people they are most able to save if they have limited capacity. And if your not vaccinated, the ability to save you will be less than the vaccinated and the people with other acute medical issues that are not COVID. That is what will happen in practice in such a regime.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#159

Earlier quoted context omitted.

But hey, grandma gets to live another year now. Who cares if the poor family never recovers after financial crisis.

I would suffer financially greatly if it brought back my grandmother, she passed from COVID December of last year. I wish she had another year. She would have had a chance to meet her great grandson. But sure, complain about the numbers in your bank account some more. Edit after being downvoted: Sure, downvote me and don’t respond over my dead grandmother, coward.

No post body was provided.

Re: Children develop robust and sustained cross-reactive immunity after Covid

#160
post #59

Earlier quoted context omitted.

Boys at least appear to be more in danger from the vaccine than the virus. https://www.theguardian.com/world/2021/sep/10/boys-more-at-r...

No they don't. The study that article references is hot garbage. https://sciencebasedmedicine.org/dumpster-diving-in-vaers-do...

"Garbage"?

> In an FDA analysis of the Optum healthcare claims database, the estimated excess risk of myocarditis/pericarditis approached 200 cases per million fully vaccinated males 16-17 years of age and 180 cases per million fully vaccinated males 12-15 years of age. [1]

This rate is close to the findings of the Høeg study (even higher, actually). [2]

On the one side we have the FDA and multiple scholarly publications largely in alignment. On the other side, we have an internet blog article with hyperbolic language and a generally unprofessional tone.

[1] https://www.fda.gov/media/153447/download

[2] https://twitter.com/TracyBethHoeg/status/1435796382841860099

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