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Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

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181–190 of 198 posts

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#181
post #171

Earlier quoted context omitted.

But South Africa has a lot of previously infected people with some degeree of natural immunization.

Sure, but so does America and the UK and so on.

Incidence in UK over the last 12 months is not comparable to large parts of Europe.

Quite astonishing how you just "confirmed" how my premise is wrong without reading what I wrote in the first place

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#182
post #113
post #29

Earlier quoted context omitted.

All this talk about "mild" cases with Omicron are failing to grasp the whole situation at two very important corners: - countries affected so far have excellent immunization rates, i.e. if I take these populations as a reference, I'm just checking how immunized people are affected. Not every country has had either a lot of cases or large/successful immunization programs - if the transmission rate in South Afrika and…

Yeah, Omicron is is still potentially a huge threat to countries which both have low vaccine uptake amongst the most at risk and avoided people being infected by previous variants. I think that might only apply to Germany, Austria and China at this point though - almost everywhere on the planet had widespread infection in past waves, and the exceptions generally have high vaccination rates by now.

No country on earth has vaccinated children under 5.

SA allegedly has had a huge amount of hospitalized children under 10 in the past weeks.

This alone can cause havoc. And suffering for the affected (incl. health workers and parents).

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#183

Earlier quoted context omitted.

I'd get it -- J&J is already known to be weaker coverage, and Omicron spreads so easily that the odds you get COVID are fairly high if you interact with people regularly. If you're looking at it from a sickness perspective, the expected value of sickness without the shot is probably higher (lower chance of many days of feeling bad vs high chance of a single day). Single person anecdote: I was quite sick from J&J and…

Sickness from the shot is not my main concern. I'd love to see the whole risk profile for my case. I have a feeling that governments are doing "booster for everybody" for political reasons. They don't want to single out particular age group.

Can you elaborate on these "political reasons"? I've heard other people say this, too, but I can't follow the reasoning. What is the government's ulterior end result of "booster for everybody" besides increased public health?

The only conspiracy I can at least follow along is the one where government is funneling money to their buddies at evil BigPharma, however there are plenty of easier ways to do this than a nation-wide vaccination campaign.

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#184
post #180
post #170

Earlier quoted context omitted.

>We're talking about a marginal effect on at best a marginal proportion of the population. You have no evidence for this statement because it is not being tested. When they test patients with severe covid they find a high level of zinc deficiency. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482607/ "The study data clearly show that a significant number of COVID-19 patients were zinc deficient. These zinc deficient…

It's bee extensively, directly tested by randomised controlled trials using vitamin supplements and no effect was found: https://www.health.harvard.edu/blog/do-vitamin-d-zinc-and-ot... "The researchers found that people receiving the supplements, whether individually or combined, had no improvement in symptoms or a faster recovery when compared with otherwise similar patients receiving neither supplement." Also it's…

I am tired of people posting ONE study and think it discredits the plethora of other studies on zinc and the immune system.

I can say several things about that zinc study; it was give too late, it was not mucosal, it was performed in non-hospitalized patients. All these patients might have been fine with Zinc but low in selenium of vitamin D.

But you will not listen.

I can ask you, is a zinc deficiency good or bad for balanced immunity?

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#185
post #172

Earlier quoted context omitted.

It means that if (big ifs!) (a) the South African peak is truly a peak and (b) vaccine-acquired immunity staves off severe illness to the same extent that infection-acquired immunity does[*], Europe is not in for “quite a ride.” As in South Africa, cases will briefly peak at a very high level, but without a corresponding high level of hospitalizations or deaths. [*] while only ~30% of SA’s population has been vaccina…

The likely higher transmissibility in combination with a generally more elderly population and vaccination gaps among older individuals in some European countries (e.g. Germany) could still spell trouble.

And experts are pretty sure by now that it will.

Also NL, DK and the London area are already putting drastic measures up. They are not doing this just for fun.

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#186
post #43

Earlier quoted context omitted.

How is this a bombshell? VAERS data isn’t reliable and should not be used to determine adverse reactions.

> VAERS data isn’t reliable and should not be used to determine adverse reactions. FDA and CDC do use VAERS as their source for estimating risk of adverse events: https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-... https://www.fda.gov/media/151733/download (page 23)

As a starting point, but they use more robust EHR data to actually investigate.

From the very first slide in your link...

>The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention (CDC) or the U.S. Food and Drug Administration (FDA)

Here are the limitations of VAERS as per the CDC.

>Limitations of VAERS:

>It is generally not possible to find out from VAERS data if a vaccine caused the adverse event

>Reports submitted to VAERS often lack details and sometimes contains errors

>Serious adverse events are more likely to be reported than non-serious events

>Numbers of reports may increase in response to media attention and increased public awareness

>VAERS data cannot be used to determine rates of adverse events

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#187

Earlier quoted context omitted.

What is the exact message? I agree this is frustrating but I don’t understand what message not getting a booster will send.

The message is stop playing political theater and creating a media cycle at every variant less it be particularly fatal one.

And how is this archived by not getting the booster?

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#188

Meta: Let say I'm 30 years old, healthy, vaccinated with JJ over 6 months ago. Denmark, Sweden, Finland have banned Moderna for younger than 30. Some countries were recommending it to people over 50. Whole communication is a mess. Should I get a booster shot? What are the pros and cons? Is there any data on that? I asked a friend doctor and she said that I should get a test for antibody count (a lab one, not garbage…

The risk of getting a myocarditis from Covid19 is 4 times higher, than from the vaccine. Billions of people got mRNA vaccines in the last year. Probably hundreds of millions of people got Covid19 last year. Can you find an overall number of deaths by vaccination versus deaths by Covid19 somewhere? Germany recommends a second vaccine shot with an mRNA vaccine for everybody who JJ as their first shot. That is only 4 we…

> The risk of getting a myocarditis from Covid19 is 4 times higher

That's not true for people under 40 who vaccinated with Moderna, see: https://www.nature.com/articles/s41591-021-01630-0/figures/2

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#189

Earlier quoted context omitted.

The message is stop playing political theater and creating a media cycle at every variant less it be particularly fatal one.

And how is this archived by not getting the booster?

They don’t try to sell a 4th one when the 3rd one doesn’t sell well.

Re: Moderna booster increased neutralizing antibody levels against Omicron ~37-fold

#190
post #29

Earlier quoted context omitted.

> When asked to grade the severity of symptoms on a scale from 1 (no symptoms) to 5 (significant symptoms), 42% (33/79) reported level 3 symptoms, whereas 11% (9/79) reported level 4 symptoms. None of the cases required hospitalisation up to 13 December 2021. I am extremely optimistic.

All this talk about "mild" cases with Omicron are failing to grasp the whole situation at two very important corners: - countries affected so far have excellent immunization rates, i.e. if I take these populations as a reference, I'm just checking how immunized people are affected. Not every country has had either a lot of cases or large/successful immunization programs - if the transmission rate in South Afrika and…

> well immunized population, some remaining x% will land in the hospital.

Compare that to that 8% fatality rate for the common cold amongst the vulnerables. Here we have 1.4% so far. It's a a ride, yes, but this ride looks good. We have such rides every single year.

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