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Japanese scientists develop vaccine to eliminate cells behind aging

japantimes.co.jp

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Re: Japanese scientists develop vaccine to eliminate cells behind aging

#201

Post by raylad »

sumedh wrote: post #199
obblekk wrote: post #194

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

> They'd work So less jobs for young people.

Jobs are not the sole way to distribute resources. In fact they are a rather recent way (in human history) to do so.

And they're going away anyway soon enough, as automation develops.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#202

Post by cblconfederate »

sumedh wrote: post #199
obblekk wrote: post #194

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

> They'd work So less jobs for young people.

or less work for everyone

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#205

Post by tux3 »

freen wrote: post #195
tux3 wrote: post #176

Earlier quoted context omitted.

I agree you should not try to live in a clean room, and you shouldn't be worried about being exposed to normal amount of germs. When you say "exposure to diverse mild pathogens actually makes your immune system less dangerous to the self", I suspect you're referring to the hygiene hypothesis that has become part of popular culture. It's important to know that that hypothesis, nowadays, is about early exposure to beni…

There is strong evidence that young children in congregate daycare have substantially stronger immune systems than children cared for at home who are only exposed to family members.

Could you link to that strong evidence?

A lookup of systematic reviews on Cochrane & Epistemonikos paints the opposite picture, with a positive correlation between daycare attendance and respiratory tract disorders or asthma.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#206

Post by ColFrancis »

sumedh wrote: post #199
obblekk wrote: post #194

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

> They'd work So less jobs for young people.

Jobs shouldn't be a limited resource.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#207

Post by dennis_jeeves »

sumedh wrote: post #199
obblekk wrote: post #194

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

> They'd work So less jobs for young people.

>So less jobs for young people.

They can live in their parent's basement! ( rule for parent =we make you young, in turn you house your brat in the basement)

By seriously, raylad's and cblconfederate's comment are very pertinent.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#208

Post by pcrh »

Waterluvian wrote: post #58
pezzana wrote: post #32

> The team, including Juntendo University professor Toru Minamino, confirmed that mice administered with the vaccine showed decreases in the zombie cells, medically known as senescent cells, and in areas affected by arterial stiffening. By now this has become a trope. "Researchers develop new treatment for {UNTREATED_DISEASE}" ... in mice. Mouse models of human disease are very limited in their predictive ability. Th…

This is well known and very well established. We don’t like experimenting on humans. It’s kind of ghoulish and evil. I get what you’re saying but it’s safe to assume that this concept is already baked into almost everyone’s discussion on matters like this.

>It’s kind of ghoulish and evil.

Experiments on humans happen very frequently. They're called "clinical trials".

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#209

Post by cellis »

raylad wrote: post #201
sumedh wrote: post #199

Earlier quoted context omitted.

> They'd work So less jobs for young people.

Jobs are not the sole way to distribute resources. In fact they are a rather recent way (in human history) to do so. And they're going away anyway soon enough, as automation develops.

Great, a gigantic underclass of people forever stuck with no upward mobility!

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#210

Post by simplestats »

_ph_ wrote: post #159
pezzana wrote: post #32

> The team, including Juntendo University professor Toru Minamino, confirmed that mice administered with the vaccine showed decreases in the zombie cells, medically known as senescent cells, and in areas affected by arterial stiffening. By now this has become a trope. "Researchers develop new treatment for {UNTREATED_DISEASE}" ... in mice. Mouse models of human disease are very limited in their predictive ability. Th…

I keep wondering if future generations will assume we had a special worship for mice considering how many diseases we tried to cure in mice :p

Oh no, future generations will curse our barbarity for doing the experiments (from the comfort of their greatly-extended lifespans).
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