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Japanese scientists develop vaccine to eliminate cells behind aging

japantimes.co.jp

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Re: Japanese scientists develop vaccine to eliminate cells behind aging

#131

Post by BurningFrog »

blip54321 wrote: post #7
JohnJamesRambo wrote: post #2

Sign me up for this the second it is available. As an aside, to spite anti vaxxers I’m on a mission to get every vaccine I can. I want my bloodstream to be like the Library at Alexandria before it burned down.

You already have the Library of Alexandria. That's your lymph nodes. What vaccines do is move some books to the front of the building, so your dentritic cells don't have to spend a few days finding them. You want the right books at the front. A mission to move all the books to the front is perhaps misguided.

That implies that each new vaccine diminishes other immunities, making it a zero sum game.

Is that actually how it works in any sense?

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#133

Post by Andy_G11 »

lordnacho wrote: post #73
dougmwne wrote: post #55

Earlier quoted context omitted.

Death represents a pretty serious destruction of human capital. If people will work forever, then why not let them live forever, much less retraining and less money spent on recruiting. This is only semi-sarcastic;)

Thank you for your application for "Junior Developer". Unfortunately we only take applicants with 100 years of JavaScript experience, 100 years of c++, at least 2M stars on GitHub contributions, and 4 PhDs in machine learning, and 200 StackOverflow points. Feel free to apply again next time Halley's comet is visible.

It would allow career diversification, though. Maybe there's a bit part going in Sly Stallone's 'Expendables 3194'?

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#134

Post by twic »

pezzana wrote: post #32

> The team, including Juntendo University professor Toru Minamino, confirmed that mice administered with the vaccine showed decreases in the zombie cells, medically known as senescent cells, and in areas affected by arterial stiffening. By now this has become a trope. "Researchers develop new treatment for {UNTREATED_DISEASE}" ... in mice. Mouse models of human disease are very limited in their predictive ability. Th…

> By now this has become a trope. "Researchers develop new treatment for {UNTREATED_DISEASE}" ... in mice.

And a twitter account:

https://twitter.com/justsaysinmice

https://jamesheathers.medium.com/in-mice-explained-77b61b598...

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#135

Post by eezurr »

The day we escape death will begin the descent into the longest dark age humanity will ever experience.

Death is necessary to allow new ideas and change to be brought into the world. Death is necessary to prevent wealth and power accumulating into fewer hands. Death is necessary for others to enjoy the right to bear and raise children.

EDIT: 2 minutes go by and this comment has already been downvoted 3+ times. At least respond before you downvote.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#136

Post by pas »

eezurr wrote: post #135

The day we escape death will begin the descent into the longest dark age humanity will ever experience. Death is necessary to allow new ideas and change to be brought into the world. Death is necessary to prevent wealth and power accumulating into fewer hands. Death is necessary for others to enjoy the right to bear and raise children. EDIT: 2 minutes go by and this comment has already been downvoted 3+ times. At lea…

Wtf is this deathcult bullshit.

Maybe in 2A Jesusland death is the only option, but in other parts of the world there are taxes and proportional representation and euthanasia.

Yes, there are problems, but saying that death (and more specifically aging with all of its shitty slow painful consequences) is great (okay, you said necessary), because it somehow "solves" other problems is a logical fallacy.

Plus, "actually" aging is one of the things that causes inequality, because wealthy people live longer thanks to having access to better healthcare, food, lifestyle, etc.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#137

Post by progman32 »

NullPrefix wrote: post #109
DeWilde wrote: post #36

Earlier quoted context omitted.

I have a rare condition related to insulin resistance and diabetes, blood sugar spikes greatly worsen my health. Discovered that vaccines spike sugar prety significantly after getting my two shots this year. Won't be getting boosters anytime soon as the side effects were gruesome.

Wouldn't that make you an antivaxxer? You surely don't want to be mixed up with that crowd, do you?

Let's debate the merit of the poster's argument instead of casting labels around. Do you think there's no scope for medical exemptions for vaccine requirements? High blood sugar is dangerous, and the OP specifically said:

> blood sugar spikes greatly worsen my health.

I'm curious what the condition is, and if there's mitigations available or if one vaccine is worse than the other.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#138

Post by mikotodomo »

mensetmanusman wrote: post #12

For the sake of discussion, which age would you want to pause at? 16, 24 for insurance reasons?

At 35. It's well known that human brain development does not end until past 30. Even before scientifically proven, intellectuals and teachers have observed anecdotes such as that singing only can begun to be mastered around the age 35.

From Lilli Lehmann's How to Sing, page 108 (originally authored in the late 1800s):

"No woman of less than twenty-four years should sing soubrette parts, none of less than twenty-eight years second parts, and none of less than thirty-five years dramatic parts; that is early enough."

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#139

Post by clairity »

InvaderFizz wrote: post #127
clairity wrote: post #98

Earlier quoted context omitted.

observing professional sports, you find that despite physical fitness/attributes having already plateaued in the early-mid twenties, people reach peak athletic performance in our late twenties when our mental facilities have fully matured and we have some modicum of experience. 27-29 is probably exactly the maximizing range, for this reason.

I'm not sure allowing the beginning of deterioration that occurs after around 25 is a good thing in this scenario. The mental maturity is most likely largely a result of experience. I'm sure it has some hormonal impact, but that doesn't automatically mean late 20s is superior if we can maintain the healing capacity of a 18 year old while increasing our experience and therefore ability to process the whole picture. I…

physical deterioration doesn’t really become evident until after/around 30 (the end of the plateau). neural development happens well into our 20s, with a long plateau into our 30s and a gradual decline after that (only becoming substantial around retirement age). growth from experience seems to be substantial into the teens, where it hits an inflection point and starts to decelerate but still climbs, albeit more slowly over time, well into our 40s at least but possibly our whole lifetimes.

we’d still get the most bang for buck if our age was ‘frozen’ in the late 20s because experience would still accumulate regardless, but we’d have maximized the combo of physical and mental growth. it’s only obvious in retrospect how immature we are at 18, both physically and mentally, or even at 25. that’s why sports is such a neat test bed, because it taxes both facilities enough to tease out these otherwise unnoticeable dynamics.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#140

Post by Retric »

BurningFrog wrote: post #131
blip54321 wrote: post #7

Earlier quoted context omitted.

You already have the Library of Alexandria. That's your lymph nodes. What vaccines do is move some books to the front of the building, so your dentritic cells don't have to spend a few days finding them. You want the right books at the front. A mission to move all the books to the front is perhaps misguided.

That implies that each new vaccine diminishes other immunities, making it a zero sum game. Is that actually how it works in any sense?

No
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