Earlier quoted context omitted.
> However, Dr Angelique Coetzee, chair of the South African Medical Association and a practising GP based in Pretoria, said it was “premature” to make predictions of a health crisis. “It’s all speculation at this stage. It may be it’s highly transmissible, but so far the cases we are seeing are extremely mild,” she said. “Maybe two weeks from now I will have a different opinion, but this is what we are seeing. So are…
Best case scenario: A virus that causes only mild symptoms, spreads quickly, and causes immunity against the original (more harmful) variants. Just lift measures and let it do its work...
Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
291–300 of 337 posts
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#292Earlier quoted context omitted.
On the other hand the vaccines could be causing more stress on the virus as they generally aren't very good. I'm saying this as someone who had the virus then the vaccine.
Not to mention the vaccines are still experimental (released under Emergence Use Authorization) and might actually have much more side effects as originally thought. And at this point I believe we can’t even be sure on the long term side effects. E.g. a Danish paper stated that in theory the spike protein used in the vaccine could increase chance of developing cancer, though as of yet this wasn’t observed yet in anim…
By the way tons of virus cause cancer, it’s not the case for a single vaccine, so this theory is very hypothetical.
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#293Earlier quoted context omitted.
>This literally reads like post apocalyptic fan fiction. I find it incredibly fascinating how fast this virus can mutate in order to throw curveballs around our natural and engineered defenses and become more efficient at killing us. How is this even possible in such a short amount of time? I thought evolution takes tens of thousands of years. It's not like viruses have giant brains with massive IQs to come up with a…
NOT a ELI5 but this should give you a reasonable understanding. Why are RNA virus mutation rates so damn high? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107253/ "RNA viruses have high mutation rates—up to a million times higher than their hosts—and these high rates are correlated with enhanced virulence and evolvability, traits considered beneficial for viruses. However, their mutation rates are almost disastrous…
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#294Earlier quoted context omitted.
>This literally reads like post apocalyptic fan fiction. I find it incredibly fascinating how fast this virus can mutate in order to throw curveballs around our natural and engineered defenses and become more efficient at killing us. How is this even possible in such a short amount of time? I thought evolution takes tens of thousands of years. It's not like viruses have giant brains with massive IQs to come up with a…
It speaks to the more serious problem with vaccine hesitancy - the more virions (individual virus 'particles') that exist, the greater the chance of a mutation that finds a way around our defenses. It's just basic evolution. The variants arise randomly and proliferate with the current major strains. The infected population adapts to reduce the transmission of the most virulent/contagious strains. Selective pressure (…
The vaccines we're currently using don't prevent infection as they do not provide sterilising immunity. To quote[1] Sunetra Gupta[2], infectious disease epidemiologist and a professor of theoretical epidemiology at the Department of Zoology, University of Oxford:
> The vaccines that we currently employ appear to be highly effective in preventing life-threatening illness but do not meaningfully contribute to the maintenance of herd immunity.
> …we find ourselves trapped by the superannuated conviction that vaccines must block infection as well as disease.
Given that, how is contrasting those who've had vaccines with those who haven't of any relevance? We have other comments in the thread (like this one[3]) pointing out that it could be immuno-compromised people that are the main source of new variants. Right now, they're among the least likely people to have been vaccinated.
[1] https://www.telegraph.co.uk/news/2021/11/24/vaccines-never-r...
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#295Earlier quoted context omitted.
You just don't build capacity against something that grows exponentially until it hits a substantial part of the overall population. Say a country like the UK, at the peak of the curve, would have 1% of their population getting sick everyday for a week or two, and 1% of that getting in a hospital (very conservative since 1% is the IFR and lots of people get out of the hospital on their legs) You might have built the…
Such an excuse. You find the doctors or find a way to get people to help. It’s an emergency. Figure it out. Forcing society to grind to an halt because some “experts” just waive their hand and give up is absurd.
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#296Earlier quoted context omitted.
>This literally reads like post apocalyptic fan fiction. I find it incredibly fascinating how fast this virus can mutate in order to throw curveballs around our natural and engineered defenses and become more efficient at killing us. How is this even possible in such a short amount of time? I thought evolution takes tens of thousands of years. It's not like viruses have giant brains with massive IQs to come up with a…
Well, isn't the common cold the result of an endless stream of "curveballs" and thus why there's no prevention for it? That is, the virus that causes the common cold is actually numerous variants (not the exact same version of the virus).
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#297Earlier quoted context omitted.
They use the greek alphabet to avoid stigmatising or politicizing the origins the various variants. They also pick names that are easy to remember and pronounce as opposed to the more technical names (ie. B.1.1.529).
Any thoughts on whether they would have done this greek alphabet thing had the first outbreak been in Africa instead of China? And why change now, when viruses (and variants) have long been named after the country or region where the first outbreak was recorded?
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#298I gotta say, COVID releases new features faster than a lot of teams do.
Which is funny because I've heard that feature branching isn't the cool way to go about things now.
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#299Twitter thread from a vaccine developer: https://threadreaderapp.com/thread/1464222680731820043.html A lot of speculation still, but it's not all bad so far.
His argument is fallacious. He's saying that since there all other variants we're susceptible to the vaccine, it's unlikely that this one is. ...and goes on to list the high number of different markers the vaccines target. Unfortunately, vaccines largely target the spike proteins, and sequencing of omicron is demonstrating that every single protein marker on the spike is changed. Vaccines will likely have a very smal…
Re: Classification of Omicron (B.1.1.529): SARS-CoV-2 Variant of Concern
#300Earlier quoted context omitted.
>If this is true, why is it when showing a chart of data it is almost impossible to pick when any of these measures went into effect? Quite exactly the opposite is actually true: it's always very clear from such charts that the measures are very effective. Some examples: https://www.canada.ca/content/dam/phac-aspc/images/corporate... https://www.nejm.org/na101/home/literatum/publisher/mms/jour... https://coronavirus.…
amazing how in many places the cases start dropping the instant the lockdown comes into place, or sometimes even slightly before, rather than ~10 days afterwards as would be expected from the incubation period. can the virus hear us?
Some cases will incubate nearly right away, and others will take more than the 2-3 weeks that are often used as quarantine periods. Getting to the 95th or 99th percentile is not the same thing as getting to the 100th percentile.
This is one of the reasons that a covid-zero strategy is effectively unimplementable.