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Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

fiercebiotech.com

351–360 of 1001 posts

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#351
post #296

Earlier quoted context omitted.

He’s vaccinated, so it seems a little dramatic to be calling OP a bad person and that they suck.

A more charitable reading is that the people involved in OP's story suck.

That’s a misreading, because GP explicitly calls out OPs behavior as bad.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#352

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

This is a good article. I'm firmly on team do-what-it-takes-to-stop-the-spread, but no one has an exit strategy. I got a booster and we have appointments for two of our three kids to get there first shot. By mid-December I'm hoping to not have to think much about it anymore. https://www.theatlantic.com/health/archive/2021/11/what-amer...

Your children do not need it - perhaps you should evaluate whether they are in an 'at risk' category like the Nordics

https://www.nature.com/articles/d41586-021-01897-w In the US, 340 children under 17 have died from Covid. Total. During the same period, 187 have died from the flu, and over 51,000 children have died from all causes:

https://www.cdc.gov/nchs/nvss/vsrr/covid_weekly/index.htm#Se...

Sweden halts Moderna: https://www.cbsnews.com/news/covid-vaccine-moderna-sweden-ha... The reason the vaccines aren't being approved for children is that there is compelling evidence that children are at greater risk from the vaccines than the virus. This is why (for example) approval for vaccination of children and teenagers is split across Europe, and the UK has restricted access to only children with known vulnerabilities:

https://www.bloomberg.com/news/articles/2021-07-19/u-k-to-gi...

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#353

Earlier quoted context omitted.

That’s a straw man argument, when you take this drug you already have 100% covid19. Presumably that means you’ll have that risk, plus additional unknown risk. Perhaps the drug works like advertised, but we’ve seen better and more successful studies for things like ivermectin and anti-body treatments. Which have a known risk profile. It’s the same for the vaccine. You still have the risk of what ever the vaccine risk…

The long term risks for either is not knowable. Hospitalisation is an acute scenario that can lead to death, negating any concerns about the long-term in the first place. The short term risk of hospitalisation in the unvaccinated versus the vaccinated is well-known. Given what we know, it still makes sense to get vaccinated, and it may make sense for those at risk of hospitalisation (vaccinated or otherwise) to take…

Actually the long term risk of the covid-19 vaccines is well understood. You will not get a side effect from the vaccines in a year from now. For all of the vaccines created for any disease, the longest recorded period between taking the vaccine and side effects presenting is 6 weeks. 3.1 billion people are fully vaccinated for covid-19, many of them have been for longer than 6 weeks.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#354

Earlier quoted context omitted.

When hospitalization rates are down. In many metro areas the ICU are still full of un-vaccinated COVID patients, which means people with normal emergencies can't get a bed. Thus, COVID precautions are necessary to reduce the rate of infection to levels that do not overwhelm the healthcare system. And all those areas that have "returned to normal" are sending their COVID patients to regions that are still masking beca…

Can you point me to a mandate anywhere with some kind of hospitalization rate cutoff? Because everywhere where there are still mask mandates, they seem to be nebulous things that will just last until it’s no longer politically popular. Oregon for example set an arbitrary date, which of course makes no sense.

Bay area (note that there are additional criteria): https://www.sfgate.com/coronavirus/article/Bay-Area-mask-man...

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#355
post #79

Kinda like ivermectin with the same mechanism

'There is no relationship at all between the two drugs, said Dr. William A Petri, professor of infectious diseases at the University of Virginia. “The only way they are alike is that they are both pills,” Petri said. Dr. Kevin J. Downes, assistant professor of pediatrics at the Perelman School of Medicine of the University of Pennsylvania, agreed, “They are dramatically different molecules. The drugs are different in…

To the user who keeps getting comments deleted for bringing up this guy's funding: please look up "ad hominem fallacy". Attacking someone making a statement says nothing about the truth of their statement

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#356

Earlier quoted context omitted.

People should get vaccinated. But at this point making claims that the vaccinated don't spread covid is not supported by the science.

On the other hand, claiming that the vaccinated spread the disease 63% less even in close household situations is supported by the science. https://www.medrxiv.org/content/10.1101/2021.10.14.21264959v...

If we made policy decisions based on a single paper, we'd all be taking HCQ and Ivermectin. And that study's confidence intervals are large. The upper bound looks like it could be in the same range for unvaccinated people.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#357
post #144

I am thinking: if and when this is approved, we have to think about distribution. This drug is fantastically effective at preventing hospitalisation and death, if administered within three days of symptom onset. That gives quite a long time! But we still need to make it easy to take. Do pharmacies give it out? ER rooms? We don't want to wait until people are hospitalised; we are trying to avoid that. So when you test…

Who is the market for this? The assumption is that you give it ASAP and people want to take it. If people aren’t interested in vaccinations they may not want it either, and the vaccines are already very effective at preventing these issues.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#358
post #301

Earlier quoted context omitted.

Pretty much the same story in South Carolina. Outside retail workers, mask usage in my hyper local area is about 2%. Life has been basically completely normal since June 2020.

I live in South Carolina as well, and I can confirm (I think you meant 2021 not 2020?). Most people in my city have been going about life as usual since ~ May if this year. Almost nobody wears masks. Everything is open. And guess what? We’re all good! The sky isn’t falling. Hospitals aren’t being overrun. Life is good, and I can remember the last time I worried or had anxiety about Covid. There seems to be a group of…

https://covid19.healthdata.org/united-states-of-america/sout...

Doesn’t look too bad so far as the USA goes, although if legal gun owners or Mexican cartel members were out there killing 40 people a day, you’d be screaming bloody murder about it

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#359

Earlier quoted context omitted.

Soo, kinda like for a vaccine? (And to clarify what I am saying, even though the vaccine does prevent death, there is still considerable push back. Not sure why it will be different for this drug)

Oh I think it will be gladly accepted by unvaccinated folk. The reason being is most unvaccinated people don’t believe it isn’t effective, they don’t like being forced to protect themselves by a bunch of moral busybodies. I just accepted as soon as we saw that covid was spreading so quickly, welp I’m gonna get that. I figured I wouldn’t be that affected by it and wasn’t. Our parents said, well if I get it I get it, a…

Nice story.

Meanwhile at least 5 million are dead - 750,000 in the US alone.

How does your story help their families?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#360

I hope this proves to be real going forward. The vaccination route seems to be hitting a deadend as a way to end the pandemic. The pill will have to be cheap and available over the counter, it makes no sense not to subsidize this.

They didn’t mention side effects at all.
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