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Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

fiercebiotech.com

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Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#191
post #149

Earlier quoted context omitted.

But that's just it, there's less than a 2% chance of dying even if you get COVID.

A 2% chance of death is actually very high risk for most people. Obviously with a name like dontcare007 I'm sure you've a huge appetite for risk that others don't.

There's a 40% chance Mr. Bond here would have died before his latest film "No Time To Die", if he had a 2% chance of death in each movie ;)

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#192

Earlier quoted context omitted.

If the consequence of not taking it is death, I think people would run to the front of the queue, though.

Soo, kinda like for a vaccine? (And to clarify what I am saying, even though the vaccine does prevent death, there is still considerable push back. Not sure why it will be different for this drug)

Oh I think it will be gladly accepted by unvaccinated folk. The reason being is most unvaccinated people don’t believe it isn’t effective, they don’t like being forced to protect themselves by a bunch of moral busybodies.

I just accepted as soon as we saw that covid was spreading so quickly, welp I’m gonna get that. I figured I wouldn’t be that affected by it and wasn’t.

Our parents said, well if I get it I get it, and if I die, I die, now let me see my grandkids. When the vaccine came out they were like sweet I’ll get it, can we stop these stupid mask wearing and social distancing crap. No, we can’t. So now us younger folk who aren’t afraid of covid aren’t getting vaccinated because we’re being forced to, and they’re going to keep up all the stupid rules like wearing masks everywhere anyways.

An anti viral drug that is this effective gives even less reason to have any mandates around vaccines, so unvaccinated people will cheer this.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#193

Earlier quoted context omitted.

But if that were an iron truth, wouldn't people be comfortable with GMOs?

GMO’s is emotional, largely based on the public image around the word ”mutant” meaning a hulk like green person that was irradiated by a James Bond villain etc

Or maybe spraying roundup on everything and suing small family farms for not using your GMO seed makes them the James Bond villain.

https://www.theguardian.com/environment/2013/feb/12/monsanto...

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#194
post #86

> This is a completely novel molecule... Then do we understand the risk profile of this thing? That sounds like the sort of innovation that people would want to be at the back of the queue for. Side effects don't have to happen in the next 6 months.

I'm not touching any Pfizer drugs with a 10 foot pole. I guess I'm one of the few actually wise humans left.

So if you get strep throat you are going to turn down the Z-pack?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#195
post #169

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

I live in Kansas and have basically forgotten COVID is a thing. The people who wanted to get vaccinated like me have and those who haven’t, haven’t. Nobody asks about it and no businesses have any sort of mask requirements. Half of the people at the grocery store wear masks and the other half don’t. Everyone seems to be getting along. Next door in Kansas City Missouri I stopped at a gas station and an employee was sh…

Pretty much the same story in South Carolina. Outside retail workers, mask usage in my hyper local area is about 2%. Life has been basically completely normal since June 2020.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#196
post #169

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

I live in Kansas and have basically forgotten COVID is a thing. The people who wanted to get vaccinated like me have and those who haven’t, haven’t. Nobody asks about it and no businesses have any sort of mask requirements. Half of the people at the grocery store wear masks and the other half don’t. Everyone seems to be getting along. Next door in Kansas City Missouri I stopped at a gas station and an employee was sh…

> I guess 5 miles difference magically makes COVID much more contagious.

No, 5 miles means you have a different government with a different policy response. (The difference itself doesn't justify either side.)

That's just inherent in the existence of political borders.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#197

Earlier quoted context omitted.

If the consequence of not taking it is death, I think people would run to the front of the queue, though.

But that's just it, there's less than a 2% chance of dying even if you get COVID.

That's the problem - "even if you get COVID".

At the start of pandemic we could have hoped that it will pass in half a year, in a year or so. Now we know that it is probably here to stay.

So eventually you will get COVID.

Depending on how long has passed after your vaccine, what variation of virus you will get, how old you are and etc will depend if it is more like 5% or 1% or so.

In my office I have 200 or so colleagues. Imagine having 4-5 funerals at the company because of this illness.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#198
post #86

> This is a completely novel molecule... Then do we understand the risk profile of this thing? That sounds like the sort of innovation that people would want to be at the back of the queue for. Side effects don't have to happen in the next 6 months.

I'm not touching any Pfizer drugs with a 10 foot pole. I guess I'm one of the few actually wise humans left.

There is selection pressure against your type of actually wise human.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#199

We had reports of people who wanted to take weird-ass drugs-of-the-day just to refuse getting vaccinated. And screaming "conspiracy" when their efficacy was not confirmed to be as high as they expected. Good that we have something that actually works, bad that some assholes will use it as an excuse not to get vaxxed, completely missing the point (among others, trying to prevent something worse than Delta).

Genuine question: is it necessary to get vaxxed if - all else held the same - the cost is not significantly higher for the antiviral? Wouldn't that cut the risk down so significantly that we can safely say, "Vaccinate if you're at-risk for your own protection, and have negligible risk otherwise"? This changes the entire risk calculation.

yes vaccination 300% (i.e. single, second, and third booster dose when ready!) Drugs that have anti-biologic properties are never good for your body, neither is allowing symptoms to fully manifest before taking drugs. People should still get the vaccines. The drugs are a backup in case the virus still overwhelms your immune system or causes it to overreact.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#200

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

It seems like we are experiencing a very slow and gradual offramp from the restrictions, rather than something that will have a clearly defined endpoint. 2021 is already "mostly normal", for me. I hope sometime in 2022 we will be back to "100% normal", but I'm not confident.

It really really depends on where you are. E.g. in my country it's almost like "normal". But that's not what you think. People just don't follow restrictions, people don't wear masks, abuse vaccination (simply skip or even buy fake vaccination certificate to fulfill government / employer requirements). The only difference from "normal" is increased workload on hospitals and daily news "over thousand people died today from covid-19".

When it's absolutely unbearable for healthcare system, government also introduces soft lockdown where restaurants / cafes / public places are closed. Then everything goes back to "normal".

I really don't see how it can be 100% normal next year. At least in here.

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