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Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

fiercebiotech.com

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Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#161

Post by dontcare007 »

HelloMcFly wrote: post #77
ed25519FUUU wrote: post #29

> Pfizer’s phase 2/3 trial randomized non-hospitalized adult COVID-19 patients who were at high risk of progressing to severe illness to receive placebo or Paxlovid, a combination of the protease inhibitors Oh, a protease inhibitor you say? I was told those were horse dewormers by the media. This whole thing is bullshit. With this much money at stake we were never going to learn the truth.

Except this is studied and dosed appropriately vs. tacking a bunch of Ivermectin and shitting your intestines out based on a half-truth you read about from Facebook.

Like what happened with Joe Rogan, oh wait, he recovered.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#162

Post by anthonypasq »

colordrops wrote: post #110

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

not exactly sure where you live but they are completely gone in most of the country. I live in a solidly blue New England state and I havent seriously thought about Covid for months.

been going to packed bars, house parties, restaurants, music festivals, concerts all with no masks

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#163

Post by jasondigitized »

dontcare007 wrote: post #136
matsemann wrote: post #106

Earlier quoted context omitted.

If the consequence of not taking it is death, I think people would run to the front of the queue, though.

But that's just it, there's less than a 2% chance of dying even if you get COVID.

Statistically you won't die from Covid but that statistic may not apply to you.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#164

Post by pwned1 »

colordrops wrote: post #110

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

Depends where you are. In many places life is back to normal and we're free human beings again.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#165

Post by kibwen »

stronglikedan wrote: post #125
RicoElectrico wrote: post #50

We had reports of people who wanted to take weird-ass drugs-of-the-day just to refuse getting vaccinated. And screaming "conspiracy" when their efficacy was not confirmed to be as high as they expected. Good that we have something that actually works, bad that some assholes will use it as an excuse not to get vaxxed, completely missing the point (among others, trying to prevent something worse than Delta).

> some assholes will use it as an excuse not to get vaxxed Well, they've succeeded in holding out long enough, now that there's no longer a good reason to get vaxxed. Because, as most people are starting to realize, the pandemic is over (at least in the US).

> the pandemic is over (at least in the US)

That remains to be seen. Thanksgiving, Christmas, and New Years will be the test of this hypothesis.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#166

Post by kevinmchugh »

colordrops wrote: post #129
kibwen wrote: post #87

Earlier quoted context omitted.

'There is no relationship at all between the two drugs, said Dr. William A Petri, professor of infectious diseases at the University of Virginia. “The only way they are alike is that they are both pills,” Petri said. Dr. Kevin J. Downes, assistant professor of pediatrics at the Perelman School of Medicine of the University of Pennsylvania, agreed, “They are dramatically different molecules. The drugs are different in…

Dr. Kevin J. Downes receives money from Pfizer: https://onlinelibrary.wiley.com/doi/full/10.1002/art.41772

Do you have an explanation for how he's wrong?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#167

Post by adrianN »

tclancy wrote: post #105
civilized wrote: post #73

Earlier quoted context omitted.

I think that crowd will hate on this new drug. It's from Big Pharma, very expensive, it's probably full of GMOs and brain-controlling chips from Bill Gates. They'll stick with their cheap, generic ivermectin.

And LUCIFERASE!

That's the enzyme you take when you have trouble digesting Satan?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#168

Post by zerkten »

orra wrote: post #108
peapod91 wrote: post #61

Earlier quoted context omitted.

That’s correct. If a positive effect in the treatment arm of the study is found to be strong enough, it is deemed unethical to continue giving patients the placebo as control. Hence, they terminate the study and proceed to the next phase of approval

That it's unethical to continue giving half the participants a placebo makes sense. I am curious though: do they ever continue with the trial, with the patients on the actual drug? Might that be useful for monitoring rare-ish side effects, even if the drug is highly effective?

They almost always do this as an approval requirement.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#169

Post by wincy »

colordrops wrote: post #110

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

I live in Kansas and have basically forgotten COVID is a thing. The people who wanted to get vaccinated like me have and those who haven’t, haven’t. Nobody asks about it and no businesses have any sort of mask requirements. Half of the people at the grocery store wear masks and the other half don’t. Everyone seems to be getting along.

Next door in Kansas City Missouri I stopped at a gas station and an employee was shouting at a woman to put on a mask, then was yelling at the same woman to leave because she refused to comply. I’m glad she didn’t see me because I literally didn’t think to bring a mask with me and needed to run to the restroom.

I guess 5 miles difference magically makes COVID much more contagious.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#170

Post by pwned1 »

anthonypasq wrote: post #162
colordrops wrote: post #110

Does anyone have a sense as to when US society will completely eliminate COVID measures? Is it just me or is there no clear exit criteria anymore? This will go on forever without exit criteria.

not exactly sure where you live but they are completely gone in most of the country. I live in a solidly blue New England state and I havent seriously thought about Covid for months. been going to packed bars, house parties, restaurants, music festivals, concerts all with no masks

Except now we have a federal government which thinks it knows best and will force medical decisions on you.
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