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Did anyone hear NPR's reporting on this? They said the early study was originally halted BECAUSE of it's positive effects at preventing hospitalization and death... very weird, I hope it is a typo or I'm understanding it wrong...
So as good as a vaccine basically?
Comparable individual outcome, worse societal outcome - you still spread it, so no reduction in overall cases, unlike a vaccine.
https://theexpose.uk/wp-content/uploads/2021/09/Pierpont-Why...
https://www.cdc.gov/mmwr/volumes/70/wr/pdfs/mm7031e2-H.pdf
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3897733
So, how could the outcome at the societal level be worse?
> There were six hospitalizations and no deaths among the 607 patients who received Paxlovid within five days of symptom onset, compared to 41 hospitalizations and 10 deaths in the placebo cohort. How does this work? You sign up for the program when you're sick and you might get meds that help you? That would really suck if a loved one was in the program and died because they happened to get the placebo.
When to Stop a Clinical Trial Early for Benefit: Lessons Learned and Future Approaches:
https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.111...
So, is this expensive and patented and does it have limited availability?
Earlier quoted context omitted.
I'm excited to hear the results of the pill among the vaccinated. Cutting the risk of severe symptoms among high-risk vaccinated people, and the risk of long covid for everyone is very important. The vaccines are great, but not silver bullets themselves.
"Long covid" is an urban legend.
Did anyone hear NPR's reporting on this? They said the early study was originally halted BECAUSE of it's positive effects at preventing hospitalization and death... very weird, I hope it is a typo or I'm understanding it wrong...
I can't imagine wanting to keep people in the control group when the experimental treatment is so dramatically effective.
So, is this expensive and patented and does it have limited availability?
> There were six hospitalizations and no deaths among the 607 patients who received Paxlovid within five days of symptom onset, compared to 41 hospitalizations and 10 deaths in the placebo cohort. How does this work? You sign up for the program when you're sick and you might get meds that help you? That would really suck if a loved one was in the program and died because they happened to get the placebo.
The alternative is what we have right now, ‘scientists’ blathering about their assumptions with the constant disclaimer that nobody really knows for real. Real science does have a price.
Part of that price is honesty on what's truly known, indicated, suggested, hypothesized, or unknown. What is "blathering" to you is intellectual integrity to others.
Did anyone hear NPR's reporting on this? They said the early study was originally halted BECAUSE of it's positive effects at preventing hospitalization and death... very weird, I hope it is a typo or I'm understanding it wrong...
> Pfizer used data on patients who were treated within three days of symptom onset as the headline finding in its press release > There were six hospitalizations and no deaths among the 607 patients who received Paxlovid within five days of symptom onset, compared to 41 hospitalizations and 10 deaths in the placebo cohort. > Like Merck, Pfizer excluded people vaccinated against COVID-19 from its late-phase study. No…
It’s similar to the antivirals for flu where you need to take it early on so it becomes habit to test early and start early.
Home labs will help with this too. Where someone could take a test, get a prescription and pickup within a few hours.